You Searched For: Gly-Arg-AMC

Catalog Number: (H-7316.0500BA)

Supplier: Bachem Americas

Description: The protein dermcidin expressed in the sweat glands is secreted into the sweat and transported to the epidermal surface. The concomitant processing of the protein yields a broad-spectrum antimicrobial 47 amino acid peptide, dermcidin-1 (DCD-1).

Supplier: Bachem Americas

Description: Sequence: Trt-Gly-OH

Supplier: Bachem Americas

Description: Fmoc-[D2]Gly-OH 1g, Molecular Formula: C17H13D2NO4, Storage Condition: Room Temperature, Cas number: 284665-11-8.

Catalog Number: (103006-184)

Supplier: Anaspec Inc

Description: Proinsulin C-peptide is the sequence of C peptide as it exists within proinsulin, the precursor to insulin which consists of insulin A chain, insulin B chain and C peptide (connecting peptide). In proinsulin, C peptide provides a means to ensure correct folding and assembly of the A and B chains. It is eventually cleaved away by proteases PC2, PC1/3 and CPE, at the flanking Arg-Arg and Lys-Arg basic residues (Arg-Arg-C peptide-Lys-Arg). Although C peptide is not present in mature insulin, it is stored in secretory granules, and eventually released into the bloodstream together with insulin in nearly equimolar amounts. Whereas insulin is metabolized quickly from circulation, C-peptide exhibits a slow turnover rate (>30 minutes). The measurement of the C-peptide is an important test for the β-cell function. In the red blood cells of type 2 diabetic patients, Na+,K+, ATPase activity is strongly related to blood C-peptide levels. C-peptide signal transduction in human renal tubular cells involves the activation of phospholipase C and PKC-δ and PKC-varepsilon, as well as RhoA, followed by phosphorylation of ERK1/2 and JNK and a parallel activation of Akt. C-peptide shows specific binding to a G-protein-coupled membrane binding site, resulting in Ca2+ influx, activation of mitogen-activated protein kinase signalling pathways and stimulation of Na+, K+ ATPase and endothelial nitric oxide synthase.
Sequence: RREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKR
MW: 3617 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: (CAAAJ64718-MC)

Supplier: Thermo Scientific Chemicals

Description: Substrate for cathepsin C

Certificates

Supplier: Bachem Americas

Description: 1G CAS: 29586-66-1 C12H26N6O3 FW: 302.38

Supplier: Bachem Americas

Description: Sequence: Fmoc-Pra-OH
Synonym(s): Fmoc-Propargyl-Gly-OH#(S)-2-(Fmoc-amino)-4-pentynoic acid

Supplier: Peprotech

Description: Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at, or adjacent to specific residues, or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes, including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Arg-C specifically cleaves at the carboxyl side of Arginine residues. Arg-C has a sulfhydryl requirement; it is activated by dithiothreitol, cysteine, or other sulfhydryl-containing reagents. The presence of calcium ions is essential. The enzyme is inhibited by oxidizing agents and sulfhydryl reactants, and by Co2+, Cu2+, Cd2+, and heavy metal ions. Recombinant Lysobacter Enzymogenes Arg-C is a 26.8 kDa protease consisting of 252 amino acid residues including a C-terminal His-Tag.

Supplier: Bachem Americas

Description: See also I-1115 and I-1395.

Catalog Number: (103918-966)

Supplier: Sino Biological

Description: A DNA sequence encoding the mouse BDNF (EDL27780.1, with mutation Arg 129 Ala, Arg 130 Ala) (Met1-Arg249) was expressed with a polyhistidine tag at the C-terminus.

Supplier: Bachem Americas

Description: 1G CAS: 60461-10-1 C11H23N5O3S FW: 305.4

Catalog Number: (G-2480.0001BA)

Supplier: Bachem Americas

Description: 1G CAS: 26607-15-8 C12H25N5O3 FW: 287.36

Supplier: Bachem Americas

Description: 1G CAS: 15706-88-4 C10H19N5O5 FW: 289.29

Supplier: Mortech Manufacturing

Description: All control slides are on Mopec IHC Enhanced Hydrophilic Adhesive Slides using Formalin Fixed Paraffin Embedded (FFPE) human tissue.

Catalog Number: (G-2375.0001BA)

Supplier: Bachem Americas

Description: The dipeptide IR showed a remarkable ACE- and renin-inhibitory activity.

Supplier: VWR International

Description: Regulators have a stainless steel barstock body and are suitable for a variety of applications where a rise in delivery pressure from a full to an empty cylinder can be tolerated.