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You Searched For: Fmoc-O-methyl-D-tyrosine


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Tyrphostin A9 ≥99% (by HPLC)

Supplier: Enzo Life Sciences
Description: Tyrphostin 9 is a selective inhibitor of the PDGF receptor tyrosine kinase (IC50=1.2 µM). It is also a potent (10 nM) uncoupler of oxidative phosphorylation.

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Z-Tyr(tBu)-OMe

Catalog Number: (C-3065.0005BA)
Supplier: Bachem Americas
Description: Sequence: Z-Tyr(tBu)-OMe
Image Unavailable-B-4115.1000BA

Fmoc-(Ring-D5)Phe-Oh

Supplier: Bachem Americas
Description: Fmoc-Phe(D₅)-OH was N-methylated and used in the synthesis of an internal standard for the quantification of the μ-opioid receptor antagonist DAMGO (H-2535) in ovine plasma samples by MALDI-TOF-MS.

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Xanthenyl linker resin 200-400 mesh

Supplier: Bachem Americas
Description: Sieber amide resin has been developed for the Fmoc-SPPS of fully t-butyl protected peptide amides. Cleavage can be achieved with 1% TFA in methylene chloride. Scavengers may be required. As N-methylation increases the acid-lability of the peptide bond, Malakoutikhah et al. employed Sieber resin for obtaining short peptide amides containing multiple MePhe residues.

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9-Fluorenylmethyl chloroformate (Fmoc chloride) 98+%

Supplier: Thermo Scientific Chemicals
Description: Base sensitive amino protecting group for solid-phase peptide synthesis

Certificates

Image Unavailable-103008-080

HIV Tat-GluR23Y

Catalog Number: (103008-080)
Supplier: Anaspec Inc
Description: The synthetic peptide (Tat-Glur23Y) contains tyrosine residues that blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. Previous research shows that Tat-Glur23Y blocks regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.
Sequence: YGRKKRRQRRRYKEGYNVYG
MW: 2634 Da
% Peak area by HPLC: 95
Storage condition: -20°C
Image Unavailable-103008-078

HIV Tat-Glur23y, Scrambled

Catalog Number: (103008-078)
Supplier: Anaspec Inc
Description: Tat-Glur23Y, scrambled is a control peptide. The synthetic peptide (Tat-Glur23Y), containing tyrosine residues, blocks phosphorylation of alpha-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid (AMPA) receptor endocytosis. However, the scrambled version does not have blockade properties. Previous studies show that Tat-Glur23Y, scrambled increase stress levels in mice, while Tat-Glur23Y reduces stress when administered.
Sequence: YGRKKRRQRRRVYKYGGYNE
MW: 2634 Da
% Peak area by HPLC: 95
Storage condition: -20°C
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(9H-Fluoren-9-yl)methyl hydrazinecarboxylate ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 35661-51-9
MDL Number: MFCD00239419
Molecular Formula: C15H14N2O2
Molecular Weight: 254.29
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 171
Storage Temperature: 0-10°C

SDS Certificates

Image Unavailable-89149-530

Galiellalactone (from unidentified fungus MST-FP1888) ≥95% (by HPLC)

Catalog Number: (89149-530)
Supplier: Enzo Life Sciences
Description: Originally isolated from Galiella rufa as a plant growth regulator. Inhibits IL-6 mediated signal transduction by blocking the binding of the activated STAT3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation site of the STAT3 transcription factor.
Image Unavailable-89158-212

Midostaurin ≥98% (by TLC)

Supplier: Enzo Life Sciences
Description: Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

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Tyrphostin A9 ≥99%

Supplier: Thermo Scientific Chemicals
Description: Selective inhibitor of PDGF receptor tyrosine kinase

Certificates

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Tricyclic amide linker resin (DL-form) 200-400 mesh

Supplier: Bachem Americas
Description: Ramage resin is highly suitable for the preparation of peptide amides by the Fmoc-strategy and is recommended for C-terminal Phe, Tyr and Ile. Cleavage has been performed with 50 % TFA in CH₂Cl₂ or 95% aqueous TFA. Scavengers may be required. Tricyclic amide linker resin has been used for the synthesis of fluorogenic substrates for continuous assay of aminopeptidase P. Bachem additionally offers the Ramage amide linker (Q-2745) to be coupled to other types of carrier resin.

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Erbstatin analog

Supplier: Thermo Scientific Chemicals
Description: An inhibitor of the EGF receptor associated tyrosine kinase

Certificates

Image Unavailable-TCF0871-5G

1-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]benzotriazole ≥98.0% (by HPLC)

Catalog Number: (TCF0871-5G)
Supplier: TCI America
Description: CAS Number: 82911-71-5
MDL Number: MFCD00074939
Molecular Formula: C21H15N3O3
Molecular Weight: 357.37
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 178
Storage Temperature: 0-10°C

SDS


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Midostaurin

Supplier: Thermo Scientific Chemicals
Description: Inhibits a variety of serine/threonine and tyrosine kinases including PKC

Certificates

Image Unavailable-TCF0936-1G

9-Fluorenylmethyl pentafluorophenyl carbonate ≥98.0% (by HPLC)

Supplier: TCI America
Description: CAS Number: 88744-04-1
MDL Number: MFCD00013261
Molecular Formula: C21H11F5O3
Molecular Weight: 406.31
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 85
Lambda max.: 300 nm (EtOH)

SDS

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