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Anti-TYR Mouse Monoclonal Antibody [clone: OCA1/812]

Supplier: Biotium
Description: This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.

Image Unavailable-75978-538

Anti-TYR Mouse Monoclonal Antibody [clone: T311 OCA1/812]

Supplier: Biotium
Description: This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.

Image Unavailable-75978-640

Anti-TYR Mouse Monoclonal Antibody [clone: T311 OCA1/812]

Catalog Number: (75978-640)
Supplier: Biotium
Description: This antibody recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
Product Image-103304-066

Formvar Film on Thin Bar Square Grids, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: A thin film of pure formvar resin coats the shiny side of a Thin Bar Square grid. Coated grids are optically checked and batch tested in the electron microscope.

Product Image-CA89167-792

Bicinchoninic Acid (BCA) Protein Assay, G-Biosciences

Supplier: G-Biosciences
Description: The Bicinchoninic Acid (BCA) protein assay is a highly sensitive colorimetric assay that is compatible with detergent solubilized protein solutions

SDS

Product Image-103303-362

Formvar Carbon Support Film on Gilder Finder Grids, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: The formvar coated grids are stabilized with an evaporated carbon film. This type of coating is excellent for specimen support, especially for ultra thin sections. All film is laid on the shiny side of the grid.

Image Unavailable-CAAA13802-36

Aluminium ammonium sulfate dodecahydrate, REacton®, Reagent Grade

Supplier: Thermo Scientific Chemicals
Description: Water and sewage purification, dyeing and printing fabrics, manufacturing of pigments, paper, artificial gems, cements, in electrolytic copper plating

Certificates

Product Image-89168-886

VWR® Drosophila Vial Plugs, Cellulose Acetate

Supplier: VWR International
Description: Bonded dense-weave cellulose acetate plugs provide a better barrier to mites with minimal shedding.

Minority or Woman-Owned Business Enterprise Product available on GSA Advantage®

Product Image-BDH7314-4

EDTA disodium salt 0.100 M (0.200 N) in aqueous solution analytical reagent, VWR Chemicals BDH®

Supplier: VWR International
Description: Suitable as a titrant. Made with deionized water.

SDS Certificates

Image Unavailable-10478-676

Anti-COMMD10 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10478-676)
Supplier: Bioss
Description: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs; rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.
Image Unavailable-TCB1801-25G

2-Bromo-3,3,3-trifluoropropene ≥97.0% (by GC)

Supplier: TCI America
Description: CAS Number: 1514-82-5
MDL Number: MFCD00077469
Molecular Formula: C3H2BrF3
Molecular Weight: 174.95
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 34
Specific Gravity (20/20): 1.66
Storage Temperature: 0-10°C

SDS Certificates

Image Unavailable-10398-962

Anti-AFP Rabbit Polyclonal Antibody

Catalog Number: (10398-962)
Supplier: Bioss
Description: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.
Product Image-10748-700

Anti-STEAP1 Rabbit Polyclonal Antibody

Catalog Number: (10748-700)
Supplier: Prosci
Description: STEAP1 Antibody: The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain; unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy. At least three isoforms of STEAP1 are known to exist.
Image Unavailable-10478-678

Anti-COMMD10 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10478-678)
Supplier: Bioss
Description: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs; rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.
Image Unavailable-10478-682

Anti-COMMD10 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10478-682)
Supplier: Bioss
Description: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs; rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.
Image Unavailable-76108-914

Anti-COMMD10 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76108-914)
Supplier: Bioss
Description: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs; rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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