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You Searched For: Cathepsin+K+substrate+(fluorogenic)


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Cathepsin K Substrate (fluorogenic)

Supplier: Thermo Scientific Chemicals
Description: A sensitive fluorogenic substrate for cathepsin K

Certificates

Product Image-89161-004

Cathepsin D&E Fluorogenic Substrate

Catalog Number: (89161-004)
Supplier: Enzo Life Sciences
Description: Quenched fluorogenic substrate for cathepsin D (kcat/Km=1.09 x 10 M-1s-1) and cathepsin E (kcat/Km=1.56 x 10 M-1s-1). Mca fluorescence is quenched by the Dnp group until cleavage separates them. Activity of the two enzymes on this substrate can be distinguished by the use of Ascaris pepsin inhibitor, which inhibits cathepsin E, but not cathepsin D. This substrate is also cleaved by MMP-2, MMP-3, MMP-9, but not MMP-1 nor MMP-13. This substrate is useful for inhibitor screening and kinetic analysis. Ex.: 320-340 nm, Em.: 393-420 nm. Mca-Pro-Leu-OH (BML-P127) can be used to calibrate for Mca fluorescence.
Product Image-89161-062

Z-VVR-AMC (Fluorogenic Substrate)

Catalog Number: (89161-062)
Supplier: Enzo Life Sciences
Description: Substrate for cathepsin S and cathepsin L
Image Unavailable-89138-362

Protease Substrates, Biotium

Supplier: Biotium
Description: Fluorogenic substrate for caspase 3, cathepsins, plasmins, granzyme B, and more.

Product Image-89160-992

OMNICATHEPSIN® Omnicathepsin* Fluorogenic Substrate

Supplier: Enzo Life Sciences
Description: Fluorogenic substrate cleaved by plasma kallikrein and kallikrein 8, but not plasmin; by papain; and by most cathepsins (cathepsins B, C/DPP-I, F, K/O2, L, L2/V, O, S, and X/Z). Ex.: 380 nm, Em.: 460 nm, although the following Ex/Em can also be used: 355,375/440,450. This substrate is useful for inhibitor screening and kinetic analysis. Also available: fluorogenic calibration standard AMC (BML-KI144).

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Tos-Gly-Pro-Lys-AMC Trifluoroacetate

Catalog Number: (I-1370.0050BA)
Supplier: Bachem Americas
Description: Tos-GPK-AMC, a fluorogenic substrate for trypsin, gingipain K, and cathepsin L.
Image Unavailable-I-1160.0050BA

Z-Phe-Arg-AMC · HCl

Supplier: Bachem Americas
Description: A fluorogenic substrate for cruzipain, plasma kallikrein and soybean trypsin-like enzyme. Z-FR-AMC was also found to be an excellent substrate for the fluorometric assay of cathepsin B, cathepsin K, and cathepsin L as well as papain. Z-FR-AMC-is also an often-used substrate for falcipain I and II.

Image Unavailable-I-1605.0050BA

H-Pro-Arg-AMC · 2 HCl

Catalog Number: (I-1605.0050BA)
Supplier: Bachem Americas
Description: PR-AMC, a fluorogenic Plasmodium falciparum dipeptidyl aminopeptidase 1 (DPAP1, cathepsin C) substrate.
Image Unavailable-I-1405.0050BA

MeOSuc-Ala-Ala-Pro-Met-AMC

Catalog Number: (I-1405.0050BA)
Supplier: Bachem Americas
Description: MeOSuc-AAPM-AMC, a fluorogenic substrate for cathepsin G.
Image Unavailable-I-1960.0050BA

Z-Leu-Arg-Amc

Supplier: Bachem Americas
Description: Z-LR-AMC, a fluorogenic substrate for cathepsin K, L, S, and V, human tissue kallikrein, and the falcipains I - III. Z-LR-AMC is the preferred substrate of falcipain II, a hemoglobin-degrading cysteine protease from Plasmodium falciparum, one of the most promising targets for antimalarial drug design.

Product Image-89146-806

Proteasome Substrate I (fluorogenic)

Catalog Number: (89146-806)
Supplier: Enzo Life Sciences
Description: Fluorogenic proteasome substrate.
Product Image-89146-802

Proteasome Substrate IV (fluorogenic)

Catalog Number: (89146-802)
Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for Alzheimer's Disease amyloid A4-generating enzymes and for the proteasome.
Product Image-89160-976

TACE Substrate (Fluorogenic)

Catalog Number: (89160-976)
Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for TACE (ADAM17) (between Ala-Val), as well as MMP-3, MMP-7, MMP-12, and MMP-17, but not for ADAM19, MMP-13, nor MMP-14. Similar substrates are also cleaved by ADAM10, ADAM8 and ADAM9, and MMP-1, -2, and -9. This quenched substrate is useful for TACE inhibitor screening and kinetic analysis. Ex: 328 nm, Em: 393 nm, although the following Ex/Em have been used: 320-340/400-420. Also available: OMNIMMP® Fluorogenic Control peptide (BML-P127).
Product Image-89160-966

OMNIMMP® Fluorescent Substrate

Catalog Number: (89160-966)
Supplier: Enzo Life Sciences
Description: Highly quenched and sensitive fluorogenic MMP substrate.
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Caspase-3 Substrate IV, Fluorogenic, Calbiochem®

Supplier: MilliporeSigma
Description: Fluorogenic caspase-3 substrate

SDS

Product Image-89146-662

Furin Convertase Substrate (fluorogenic)

Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for furin/SPC1/PACE/PCSK3 and other subtilisin/kexin-like proprotein convertases such as Kex2, SPC2/PC2/PCSK2, SPC3/PCSK1, PACE4/SPC4/PCSK6, SPC5/PC4/PCSK4, SPC6/PC5/PC6/PCSK5, and SPC7/LPC/PC7/PC8/PCSK7. Can be used on live cells. Ex: 340-360 nm, Em: 440-460 nm.

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