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Supplier: Enzo Life Sciences
Description: A highly potent, cell-permeable inhibitor of cathepsin K (IC50=51 nM).

Catalog Number: (89164-838)
Supplier: Enzo Life Sciences
Description: PLD inhibitor.


Catalog Number: (89161-796)
Supplier: Enzo Life Sciences
Description: A potent inhibitor of the dual specificity phosphatase JSP-1 (IC50=18µM).


Catalog Number: (89161-802)
Supplier: Enzo Life Sciences
Description: PTP1B inhibitor


Supplier: Enzo Life Sciences
Description: Structurally novel SIRT2 inhibitor (IC50=56.7µM).

Supplier: Enzo Life Sciences
Description: HDAC inhibitor developed at Enzo Life Sciences. Inhibits HDAC activity in HeLa nuclear extracts (IC50=5-10µM).

Catalog Number: (89158-242)
Supplier: Enzo Life Sciences
Description: BML-277 is a highly selective inhibitor of Chk2 (IC50=15nM). It displays potent radioprotective activity and prevents apoptosis of human T cells subjected to ionizing radiation (EC50= 3-7.6µM). Useful tool for dissecting the role of Chk2 in cellular signaling.


Supplier: Enzo Life Sciences
Description: A SIRT1 activator.

Supplier: Enzo Life Sciences
Description: Potent lipoxin A₄ agonist, equiactive as LXA₄ in inhibition of LTB₄ induced PMNL chemotaxis (IC₅₀ = 5 nM).

Catalog Number: (89164-834)
Supplier: Enzo Life Sciences
Description: Potent and selective inhibitor of phospholipase D2 (PLD2) in cellular (PLD1 IC50 = 1900nM Calu-1 cells; PLD2 IC50 = 90nM HEK293-gfpPLD2 cells) and in vitro (hPLD1 IC50 = >20’000nM; hPLD2 IC50 = 500nM) assays.


Catalog Number: (89158-726)
Supplier: Enzo Life Sciences
Description: Immunization and blocking peptide for Glutamic Acid Decarboxylase (GAD) antibodies (BML-GC3008 and BML-GC3108). The pentadecapeptide corresponds to the C-terminal residues [Cys+]572-585 of rat GAD65. The sequence is wholly conserved at the C-terminus of rat GAD67, mouse, pig and human GAD65/67, cat GAD67, and in human GAD-2.


Catalog Number: (89158-728)
Supplier: Enzo Life Sciences
Description: Immunization and blocking peptide for Glutamic Acid Decarboxylase (GAD) antibody (BML-GC3208). The tetradecapeptide corresponds to the N-terminal residues 4-17 of rat GAD65. The sequence is wholly conserved human GAD65.


Catalog Number: (89160-968)
Supplier: Enzo Life Sciences
Description: Reference peptide for OmniMMPTM fluorogenic substrate (BML-P126) and TACE (ADAM17) fluorogenic substrate (BML-P132). Ex.: 328 nm, Em.: 393 nm. The following Ex/Em have also been used: 320 – 340/400 – 420.


Catalog Number: (89160-348)
Supplier: Enzo Life Sciences
Description: Fluor de Lys®-HDAC8 is a fluorogenic, diacetylated peptide substrate for HDAC8 (histone deacetylase-8). Based on residues 379-382 of p53 (Arg-His-Lys(Ac)-Lys(Ac)), a site of regulatory acetylation by the p300 and CBP acetyltransferases (lysines 381, 382), it was the best for HDAC8 from among a panel of substrates patterned on p53, histone H3 and histone H4 acetylation sites. Fluor de Lys®-HDAC8 is deacetylated by HDAC8 at a rate of more than 10-fold that of the acetylated lysine substrate, Fluor de Lys® (BML-KI104; substrates both at 100 µM). Although named because of HDAC8’s preference for it, it is also an excellent substrate for SIRT1 (BMl-SE239; 5x the rate of BML-KI104 at 25 µM, 0.5 mM NAD+), SIRT2 and HeLa Nuclear Extract (BML-KI140; 3x KI-104 rate, 25 µM). Must be used in conjunction with Fluor de Lys® Developer II (BML-KI176). Sufficient for 100-200 assays of human recombinant HDAC8 (BML-SE145; 1 U/well, 50-100 µM substrate).


Catalog Number: (89157-384)
Supplier: Enzo Life Sciences
Description: Sequence derived from human/mouse dishevelled-2 [Cys+600-614]. Used to generate the rabbit polyclonal antiserum to dishevelled-2 (BML-DA4270). The peptide is suitable for use in negative control (antibody blocking) experiments in Western blotting and immunohistochemistry.


Catalog Number: (89160-114)
Supplier: Enzo Life Sciences
Description: Synthetic peptide corresponding to amino acid residues [12-25] + Cys-NH2 of human heme oxygenase-1. Complementary peptide to rabbit polyclonal antibody (BML-HC3001) for use in control experiments. Preincubation of antibody with this peptide abolishes the antibody reactivity with HO-1 protein.


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