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Image Unavailable-TCD3729-1G

4,5-Difluoro-o-phenylenediamine ≥97.0% (by GC, titration analysis)

Catalog Number: (TCD3729-1G)
Supplier: TCI America
Description: CAS Number: 76179-40-3
MDL Number: MFCD00061131
Molecular Formula: C6H6F2N2
Molecular Weight: 144.12
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Melting point (°C): 132

SDS Certificates


Image Unavailable-10486-610

Anti-SASS6 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10486-610)
Supplier: Bioss
Description: SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle; it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
Image Unavailable-10780-928

Rat Recombinant IL-6 (from E. coli)

Supplier: Peprotech
Description: IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Rat IL-6 is a 21.7 kDa protein containing 188 amino acid residues.

Product Image-10085-876

Anti-DKK1 Rabbit Polyclonal Antibody

Catalog Number: (10085-876)
Supplier: Proteintech
Description: DKK1, also named a SK and Dickkopf-1, belongs to the dickkopf family. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. SDS-PAGE and Western blot analysis demonstrated that DKK1 is expressed as a 35-kD doublet protein, which is larger than the deduced molecular mass of 26 kD. Sometime DKK1 is expressed as a 42- to 50-kD secreted protein, with little change observed after glycanase treatment.
Image Unavailable-TCD4623-5G

2,3-Difluoro-5-(trifluoromethyl)pyridine ≥98.0% (by GC)

Supplier: TCI America
Description: CAS Number: 89402-42-6
MDL Number: MFCD04972837
Molecular Formula: C6H2F5N
Molecular Weight: 183.08
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 104
Flash Point (°C): 100
Specific Gravity (20/20): 1.49

SDS

Image Unavailable-TCD4535-25G

3,4-Difluoro-4'-(trans-4-propylcyclohexyl)biphenyl ≥98.0%

Supplier: TCI America
Description: CAS Number: 85312-59-0
MDL Number: MFCD09838999
Molecular Formula: C21H24F2
Molecular Weight: 314.42
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 68

SDS

Image Unavailable-TCD4733-5G

2,4-Difluoro-6-nitroaniline ≥98.0% (by GC)

Catalog Number: (TCD4733-5G)
Supplier: TCI America
Description: 2,4-Difluoro-6-nitroaniline, Purity: >98.0%(GC), CAS Number: 364-30-7, Molecular Formula: C6H4F2N2O2, Molecular Weight: 174.11, Form: Crystal-Powder, Solid, Color: Pale yellow - Deep yellow, Size: 5G

SDS


Image Unavailable-76110-382

Anti-SASS6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76110-382)
Supplier: Bioss
Description: SAS-6 (spindle assembly abnormal protein 6 homolog, HsSAS-6) is a 657 amino acid protein encoded by the human gene SAS6. SAS-6 is a component of the centrosome that contains one PISA (present in SAS-6) domain. LK4, SAS-6, CPAP and other centriole related proteins are required at different stages of procentriole formation and were associated with different centriolar structures. SAS-6 associates only transiently with nascent procentrioles, whereas CEP135 and CPAP form a core structure within the proximal lumen of both parental and nascent centrioles. SAS-6 is necessary for procentriole formation in human cell lines and is localized asymmetrically next to the centriole at the onset of procentriole formation. SAS-6 levels oscillate during the cell cycle; it is degraded in mitosis starting at anaphase, and it accumulates again at the end of the following G1 phase. The anaphase-promoting complex targets SAS-6 for degradation by the 26S Proteasome, and a KEN box in the C-terminus of SAS-6 is necessary for its degradation. Increased SAS-6 levels promoted the formation of multiple procentrioles forming next to a single centriole.
Image Unavailable-CAAAB24389-03

4-Bromo-2,2-difluoro-1,3-benzodioxole 97%

Supplier: Thermo Scientific Chemicals
Description: 4-Bromo-2,2-difluoro-1,3-benzodioxole 97%

Certificates

Image Unavailable-TCB3073-5G

2-Bromo-1,3-difluoro-5-iodobenzene ≥98.0%

Supplier: TCI America
Description: CAS Number: 155906-10-8
MDL Number: MFCD06797752
Molecular Formula: C6H2BrF2I
Molecular Weight: 318.89
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 66

SDS

Product Image-10082-234

Anti-SUMO2 + SUMO3 Rabbit Polyclonal Antibody

Catalog Number: (10082-234)
Supplier: Proteintech
Description: Ubiquitin is most famous for its function in targeting proteins for degradation by the 26S proteasome, ubiquitin needs to be attached to a substrate in chains (polyubiquitylation) before being recognized by proteasome. Similarly, SUMO (small ubiquitin-related modifier) can be linked to substrates in chains (polysumoylation), SUMO modification has been implicated in many important cellular processes including the control of genome stability, signal transduction, targeting to and formation of nuclear compartments, cell cycle and meiosis. There are 4 confirmed SUMO isoforms in human, SUMO-1, SUMO-2, SUMO-3 and SUMO-4. SUMO-2 and SUMO-3 are nearly identical but are distinct from SUMO-1. SUMO2/3 conjugation was recently widely involved in neuroprotective activities. A substitution (M55V) of SUMO4 was strongly associated with the pathogenesis of type 1 diabetes (T1D) involving NF kappa B related mechanisms.
Image Unavailable-TCB3926-1G

1-Bromo-2,5-difluoro-4-nitrobenzene ≥98.0% (by GC)

Supplier: TCI America
Description: CAS Number: 167415-27-2
MDL Number: MFCD00042184
Molecular Formula: C6H2BrF2NO2
Molecular Weight: 237.99
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 58

SDS

Image Unavailable-TCD4897-1G

4,4-Difluoro-1,3-dimethyl-4-bora-3a,4a-diaza-s-indacene ≥98.0% (by GC)

Supplier: TCI America
Description: 4,4-Difluoro-1,3-dimethyl-4-bora-3a,4a-diaza-s-indacene, Purity: >98.0%(GC), CAS Number: 154793-49-4, Molecular Formula: C11H11BF2N2, MW: 220.03, Form: Crystal-Powder, Solid, Color: Reddish yellow-Deep yellow red, Size: 200MG

SDS Certificates

Image Unavailable-TCD4526-1G

1,2-Difluoro-4-(methylsulfonyl)benzene ≥98.0% (by GC)

Supplier: TCI America
Description: CAS Number: 424792-57-4
MDL Number: MFCD04037934
Molecular Formula: C7H6F2O2S
Molecular Weight: 192.18
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 77

SDS

Image Unavailable-10088-008

Anti-GZMB Rabbit Polyclonal Antibody

Catalog Number: (10088-008)
Supplier: Proteintech
Description: GZMB(Granzyme B) is also named as CGL1, CSPB, CTLA1, GRB and belongs to the Granzyme subfamily. This enzyme is necessary for target cell lysis in cell-mediated immune responses. The cytotoxic lymphocyte protease granzyme B (GzmB) can promote apoptosis through direct processing and activation of members of the caspase family. GzmB can also cleave the BH3-only protein, BID, to promote caspase-independent mitochondrial permeabilization.GzmB induces laminB degradation in isolated nuclei less efficiently than GzmA.This full length protein has 2 glycosylation sites and a signal peptide.Unglycosylated human granzyme B is 26 kDa and g high mannose glycosylated is 32 kDa and only 32kDa or smaller forms of granzyme B are accumulated within nuclei.
Product Image-10088-020

Anti-HABP2 Rabbit Polyclonal Antibody

Catalog Number: (10088-020)
Supplier: Proteintech
Description: HABP2 is also named as HGFAL, PHBP and belongs to the peptidase S1 family. It can activate coagulation factor VII and prourokinase and release the vasoactive peptide bradykinin by cleaving kininogen and is an important role in the regulation of the haemostasis system as well as fibroproliferative inflammatory processes . HABP2 is present as the 70 kDa inactive single chain precursor in human plasma and transforms to the active two chain form, 50 kDa heavy chain and 27 kDa light chain,and the 50 kDa heavy chain changes to two 26 kDa fragments, and 27 kDa light chain to 17 kDa and 8 kDa fragments, which are all bridged by disulfide linkages, by autocleavage.
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