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Image Unavailable-10375-296

Anti-INPP5D Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10375-296)
Supplier: Bioss
Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Image Unavailable-10417-342

Anti-PDPK1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10417-342)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Image Unavailable-10417-338

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10417-338)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Image Unavailable-CAAAA10461-0J

1-Bromopropane 99% ACS

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00000254 Beilstein Registry No.: 505936

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Image Unavailable-CAAA39106-14

Iodine monobromide ≥98%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011353 Beilstein Registry No.: 3902973 Fieser: 1,501 2,224 17,152 18,193 20,200

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Product Image-77618-836

VWR® Ion Selectrive Electrodes

Catalog Number: (77618-836)
Supplier: SCHULER SCIENTIFIC
Description: The VWR® Ion Selective Electrodes (ISE) allow for the measurement of concentration of a specific ion.

New Product


Image Unavailable-CAAAA13388-18

1-Bromo-3-methyl-2-butene 90+% stabilized

Supplier: Thermo Scientific Chemicals
Description: 1-Bromo-3-methyl-2-butene 90+% stabilized

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Image Unavailable-10368-530

Anti-INPP5D Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10368-530)
Supplier: Bioss
Description: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Image Unavailable-TCT2634-25G

Triethylene glycol-2-bromoethyl methyl ether ≥95.0%

Supplier: TCI America
Description: CAS Number: 110429-45-3
Molecular Formula: C9H19BrO4
Molecular Weight: 271.15
Purity/Analysis Method: >95.0% (GC)
Form: Clear Liquid
Color: Very Pale Yellow
Specific Gravity (20/20): 1.29
Storage Temperature: 0-10°C

SDS Certificates

Image Unavailable-CAAAA15319-14

ω-Bromo-4-fluoroacetophenone 97%

Supplier: Thermo Scientific Chemicals
Description: ω-Bromo-4-fluoroacetophenone 97%

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Image Unavailable-TCD3831-25G

Diethylene glycol-2-bromoethyl methyl ether ≥94.0%

Supplier: TCI America
Description: CAS Number: 72593-77-2
Molecular Formula: C7H15BrO3
Molecular Weight: 227.10
Purity/Analysis Method: >94.0% (GC)
Form: Clear Liquid
Boiling point (°C): 65
Specific Gravity (20/20): 1.31
Storage Temperature: <0°C

SDS Certificates

Image Unavailable-CA8.01676.0250

1-Bromodecane for synthesis, Sigma-Aldrich®

Catalog Number: (CA8.01676.0250)
Supplier: MilliporeSigma

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Image Unavailable-TCN0073-025G

Naringin ≥90.0% (by titrimetric analysis)

Catalog Number: (TCN0073-025G)
Supplier: TCI America
Description: CAS Number: 10236-47-2
MDL Number: MFCD00148888
Molecular Formula: C27H32O14
Molecular Weight: 580.54
Purity/Analysis Method: >90.0% (T)
Form: Crystal
Specific rotation [a]20/D: -84 deg (C=2, EtOH)

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Image Unavailable-10347-034

Anti-BMX Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10347-034)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Product Image-10411-166

Anti-BMX Rabbit Polyclonal Antibody

Catalog Number: (10411-166)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Image Unavailable-10411-178

Anti-BMX Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10411-178)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
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