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Zinc ≥99.99% (metals basis), ingot, Length: 345 mm (13.6 in)

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011291

Certificates

Image Unavailable-76082-728

Anti-PDPK1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76082-728)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Product Image-CAAA35714-09

Praseodymium tribromide, ultra dry ≥99.99% (REO, rare earth oxide basis)

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00049762

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Resorufin-β-D-galactopyranoside

Catalog Number: (103011-314)
Supplier: Anaspec Inc
Description: Unlike FDG that requires a two-step hydrolysis to generate maximum fluorescence, resorufin β-D-galactopyranoside requires only a single-step hydrolysis reaction to attain full fluorescence. This substrate is especially useful for sensitive enzyme measurements in ELISAs. The relatively low pKa (~6.0) of resorufin (the enzymatic hydrolysis product of resorufin galactoside) with Ex/Em=573/585 nm permits continuous measurement of enzymatic activity. Resorufin galactoside has also been used to quantitate β-galactosidase activity in single yeast cells by flow cytometry and to detect immobilized β-galactosidase activity.
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1-Bromo-3-phenoxypropane 98%

Supplier: Thermo Scientific Chemicals
Description: 1-Bromo-3-phenoxypropane 98%

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Product Image-10073-194

Anti-BTK Mouse Monoclonal Antibody [clone: 7F12H4]

Catalog Number: (10073-194)
Supplier: Prosci
Description: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases.All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini.BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation.
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Benzyl-2-bromoethyl ether 97%

Supplier: Thermo Scientific Chemicals

Certificates

Product Image-76262-946

Anti-PIK3CB Rabbit Polyclonal Antibody

Catalog Number: (76262-946)
Supplier: Rockland Immunochemical
Description: PIK3CB is a catalytic subunit of phosphoinositide-3-kinase beta. PIK3CB catalyzes the production of phosphatidylinositol-3,4,5-triphosphate by phosphorylating phosphatidylinositol (PI), phosphatidylinositol-4-phosphate (PIP) and phosphatidylinositol-4,5-bisphosphate (PIP2). Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration and cell survival. PTEN reverses this process. PI3K signaling pathway is constitutively activated in human cancers that have loss of function of PTEN. Furthermore, PI3KCB down regulation can suppress cell growth in malignant gliomas. Anti-PIK3C beta Antibody is suitable for researcher in Cancer, Immunology and Nuclear Signaling research.
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ω-Bromoacetophenone 98%

Supplier: Thermo Scientific Chemicals
Description: ω-Bromoacetophenone 98%

Certificates

Image Unavailable-10451-386

Anti-FANK1 Rabbit Polyclonal Antibody

Catalog Number: (10451-386)
Supplier: Bioss
Description: FANK1 (fibronectin type III and ankyrin repeat domains 1), also known as HSD13, is a 345 amino acid nuclear and cytoplasmic testis-specific protein found primarily in pachytene spermatocytes and round spermatids. Containing six ANK repeats and a single fibronectin type-III domain, FANK1 undergoes alternative splicing events to form three isoforms. Possessing DNA binding activity, FANK1 is suggested to act as a transcription factor and may regulate gene expression during spermatogenesis. The gene encoding FANK1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
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1-Bromodecane ≥98.0%

Supplier: TCI America
Description: CAS Number: 112-29-8
MDL Number: MFCD00000221
Molecular Formula: C10H21Br
Molecular Weight: 221.18
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 139
Melting point (°C): -30
Flash Point (°C): 94
Specific Gravity (20/20): 1.07

SDS Certificates

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1-Bromo-2-methylpropane 98+%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00000217 Beilstein: 1730915 Slightly soluble in water. Miscible with alcohol, ether

Certificates

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α,2-Dibromo-5-fluorotoluene 97%

Supplier: Thermo Scientific Chemicals
Description: α,2-Dibromo-5-fluorotoluene 97%

Certificates

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1-Bromoundecane ≥98.0%

Supplier: TCI America
Description: CAS Number: 693-67-4
MDL Number: MFCD00000223
Molecular Formula: C11H23Br
Molecular Weight: 235.21
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 138
Melting point (°C): -9
Flash Point (°C): 113
Specific Gravity (20/20): 1.06

SDS Certificates

Image Unavailable-CA8.01549.0250

1-Bromo-2-methylpropane for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma

SDS Certificates

Image Unavailable-76080-702

Anti-PDPK1 Ser393 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76080-702)
Supplier: Bioss
Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
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