You Searched For: 3,4,5-Trifluorobenzyl+bromide


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Supplier: Thermo Scientific Chemicals
Description: α-Bromo-4-nitrotoluene 97+%
Supplier: Thermo Scientific Chemicals
Description: α-Bromo-2-nitrotoluene 98+%
Catalog Number: (10088-920)
Supplier: Proteintech
Description: INPP5D, also named as SHIP, SHIP1, SIP-145 and hp51CN, belongs to the inositol-1,4,5-trisphosphate 5-phosphatase family. INPP5D is phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. INPP5D acts as a negative regulator of B-cell antigen receptor signaling. It mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. INPP5D acts as a negative regulator of myeloid cell proliferation/survival and chemotaxis, mast cell degranulation, immune cells homeostasis, integrin alpha-IIb/beta-3 signaling in platelets and JNK signaling in B-cells. INPP5D regulates proliferation of osteoclast precursors, macrophage programming, phagocytosis and activation and is required for endotoxin tolerance. It is involved in the control of cell-cell junctions, CD32a signaling in neutrophils and modulation of EGF-induced phospholipase C activity. It is a key regulator of neutrophil migration, by governing the formation of the leading edge and polarization required for chemotaxis. It modulates FCGR3/CD16-mediated cytotoxicity in NK cells. It mediates the activin/TGF-beta-induced apoptosis through its Smad-dependent expression. INPP5D may also hydrolyze PtdIns(1,3,4,5)P4, and could thus affect the levels of the higher inositol polyphosphates like InsP6.


Supplier: MilliporeSigma
Description: Clear crystals.

SDS

Catalog Number: (TCB1002-100G)
Supplier: TCI America
Description: CAS Number: 589-15-1
MDL Number: MFCD00000179
Molecular Formula: C7H6Br2
Molecular Weight: 249.93
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 124
Melting point (°C): 61

Supplier: Thermo Scientific Chemicals
Description: Iodine monobromide 98%
Catalog Number: (CAPI28310)
Supplier: Thermo Scientific
Description: Thermo Scientific Octyl-beta-Glucoside is a nonionic detergent that has been widely used for membrane protein solubilization.

Supplier: Thermo Scientific Chemicals
Description: Bromocyclopropane 99%
Catalog Number: (10411-182)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00011323 Beilstein Registry No.: 3587158 Fieser: 1,450 2,214 3,154 18,180
Catalog Number: (10347-026)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Catalog Number: (10351-576)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Catalog Number: (10411-180)
Supplier: Bioss
Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].


Supplier: TCI America
Description: CAS Number: 528-50-7
MDL Number: MFCD00136034
Molecular Formula: C12H22O11
Molecular Weight: 342.30
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Specific rotation [a]20/D: 34 deg (C=8, H2O)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00000353 Beilstein Registry No.: 516231
Catalog Number: (104028-752)
Supplier: Alkali Scientific
Description: In addition to its neutralizing capabilities, the CellPro™ Neutralizing Solution is compatible with a wide range of laboratory techniques, including Southern and Northern blotting, where it plays a crucial role in preparing samples for hybridization to labeled probes. The solution's effectiveness in neutralizing harsh chemical conditions makes it an indispensable component in molecular biology workflows, supporting the accurate detection and analysis of nucleic acids.


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