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You Searched For: 2,6-Dichloro-3-pyridineboronic+acid


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Product Image-10750-172

Anti-COPS8 Rabbit Polyclonal Antibody

Catalog Number: (10750-172)
Supplier: Prosci
Description: CSN8 Antibody: The COP9 signalosome (CSN) is an evolutionarily conserved protein complex of the eight subunits that interacts with deubiquitinating enzymes and protein kinases and is highly homologous to the lid sub-complex of 26S proteasome. The CSN complex is an essential regulator of the ubiquitin conjugation pathway by mediating the deneddylation of the SCF-type E3 ligase complexes, which leads to a decrease in ubiquitin ligase activity of SCF-comlpexes such as SCF, CSA or DDB2. It is also involved in phosphorylation of p53, c-jun/JUN, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN8 encodes the smallest and the least conserved but first identified subunit of CSN. Recent studies show CSN8 is essential for Drosophila development and is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.
Image Unavailable-TCD3746-5G

2,4-Dichloro-6,7-dimethoxyquinazoline ≥98.0% (by HPLC, total nitrogen)

Catalog Number: (TCD3746-5G)
Supplier: TCI America
Description: CAS Number: 27631-29-4
MDL Number: MFCD00051733
Molecular Formula: C10H8Cl2N2O2
Molecular Weight: 259.09
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 175

SDS


Image Unavailable-TCD2958-5G

2,4-Dichloro-6-methylpyrimidine ≥98.0% (by GC)

Supplier: TCI America
Description: CAS Number: 5424-21-5
MDL Number: MFCD00006064
Molecular Formula: C5H4Cl2N2
Molecular Weight: 163.00
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 219
Melting point (°C): 47
Flash Point (°C): 230

SDS

Image Unavailable-CAAAA11879-30

2,3-Dichloro-5,6-dicyano-p-benzoquinone 98%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00001593 Beilstein Registry No.: 747939 Fieser: 1,215 14,126 15,125 16,120 18,130 19,121 20,137 21,164

Certificates

Image Unavailable-TCD3721-25G

2,4-Dichloro-5-nitropyrimidine ≥98.0%

Supplier: TCI America
Description: CAS Number: 49845-33-2
MDL Number: MFCD00127867
Molecular Formula: C4HCl2N3O2
Molecular Weight: 193.97
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 139
Flash Point (°C): 110
Freezing point (°C): 28
Storage Temperature: 0-10°C

SDS Certificates

Image Unavailable-TCD3423-5G

DL-1,4-Dichloro-2,3-butanediol ≥98.0%

Supplier: TCI America
Description: CAS Number: 2419-73-0
Molecular Formula: C4H8Cl2O2
Molecular Weight: 159.01
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 152
Melting point (°C): 77

SDS Certificates

Product Image-10748-814

Anti-UBQLN4 Rabbit Polyclonal Antibody

Catalog Number: (10748-814)
Supplier: Prosci
Description: CIP75 Antibody: The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins. The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation. One such protein is CIP75, also known as ubiquilin-4, interacts with a number of proteins such as Ataxin-1 and Connexin-43, resulting in an increased rate of turnover of these proteins. Overexpression CIP75 led to a significant reduction of Connexin-43 half-life, with the opposite being observed in siRNA knockdown experiments. CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteosome complex and a C-terminal UBA domain which appears to mediate its interaction with Connexin-75. At least three isoforms of CIP75 are known to exist.
Image Unavailable-CAAA46665-06

Dichloro[9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene]palladium(II) Pd 12.1%, crystalline solid

Supplier: Thermo Scientific Chemicals
Description: Dichloro[9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene]palladium(II), Pd 14.1%

Certificates

Image Unavailable-76219-748

5,6-Dichloropyridin-3-ol ≥98.0% (by GC)

Catalog Number: (76219-748)
Supplier: TCI America
Description: 2,3-Dichloro-5-hydroxypyridine, Purity: >98.0%(GC), CAS number: 110860-92-9, Molecular Formula: C5H3Cl2NO, Molecular Weight: 163.99, Synonyms: 5,6-Dichloro-3-pyridinol, Form: Crystal - Powder, White - Slightly pale reddish yellow, Size: 1G
Product Image-89162-330

PR11

Catalog Number: (89162-330)
Supplier: Enzo Life Sciences
Description: Studies have demonstrated that PR39, a proline/arginine rich 39 amino acid antibacterial peptide originally derived from porcine bone marrow, exhibits a broad spectrum of biological activities, including the ability to induce angiogenesis and to limit inflammatory damage in a variety of animal models. The angiogenic effect is in part explained by the ability of PR39 to inhibit proteasome-dependent degradation of the transcription factor HIF-1a, while anti-inflammatory activity is associated with inhibition of IκBα degradation that in turn prevents activation of NFκB-dependent gene expression. The activities of PR39 reside in the N-terminal portion of the molecule encompassed by PR11. The most recent findings have demonstrated that PR39 is a non-competitive and reversible inhibitor of the proteasome function, which is achieved by a unique allosteric mechanism allowing for specific inhibition of degradation of selected proteins without affecting total proteasome-dependent proteolysis. A proline-arginine-rich 11 amino acid peptide derived from the naturally occurring peptide antibiotic PR39. PR39 has been shown to act as an inhibitor of both 20S and 26S proteasomes with proposed selectivity for the inhibition of the degradation of IκBα, HIF-1a and certain other proteins. PR39 has been reported to inhibit the proteasomal degradation of IκBα without effecting overall proteasome activity, or degradation of p21Cip1/Waf1 and c-fos, cell-cycle genes regulated by proteasome-dependent degradation. In vitro studies have demonstrated PR39 to be an efficient inhibitor of all three activities of the 20S proteasome. Unlike MG132 and lactacystin, long-term exposure to PR39 shows little toxicity or induction of HSP-70. In mouse models of myocardial infarction it has been shown that infusion with PR11 results in a significant reduction of myocardial infarct size. PR39, PR11 and related peptides may therefore provide novel means to regulate cellular function and the control of NF-κB-dependent gene expression for therapeutic purposes.
Image Unavailable-TCD2421-005G

2,3-Dichloro-5,8-dihydroxy-1,4-naphthoquinone ≥97.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 14918-69-5
MDL Number: MFCD00075261
Molecular Formula: C10H4Cl2O4
Molecular Weight: 259.04
Purity/Analysis Method: >97.0% (HPLC,T)
Form: Crystal
Melting point (°C): 201

SDS Certificates

Image Unavailable-CAAAAL14835-03

1,4-Dichloro-5,6,7,8-tetrahydro-5,8-ethanophthalazine 97%

Supplier: Thermo Scientific Chemicals
Description: 1,4-Dichloro-5,6,7,8-tetrahydro-5,8-ethanophthalazine 97%

Image Unavailable-TCD3547-25G

3,4-Dichloro-1,2,5-thiadiazole ≥98.0%

Catalog Number: (TCD3547-25G)
Supplier: TCI America
Description: CAS Number: 5728-20-1
MDL Number: MFCD00010072
Molecular Formula: C2Cl2N2S
Molecular Weight: 155.00
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 158
Flash Point (°C): 100
Specific Gravity (20/20): 1.65

SDS


Image Unavailable-10092-856

Anti-PRSS8 Rabbit Polyclonal Antibody

Catalog Number: (10092-856)
Supplier: Proteintech
Description: PRSS8(protease, serine, 8) displays trypsin-like enzymatic activities by hydrolyzing peptidyl fluorogenic substrates such as D-Pro-Phe-Arg-AMC. This trypsinlike enzymatic activity can be inhibited by aprotinin, antipain, leupeptin, and benzamidine. It is a heterodimer of two chains, light and heavy, which are held by a disulfide bond. PRSS8 is also named as CAP1 and belongs to the peptidase S1 family.
Image Unavailable-TCD0343-001G

2,5-Dichloro-p-benzoquinone ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 615-93-0
MDL Number: MFCD00041736
Molecular Formula: C6H2Cl2O2
Molecular Weight: 176.98
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 161

SDS

Image Unavailable-TCD3592-200MG

Dichloro(1,5-cyclooctadiene)platinum(II)

Supplier: TCI America
Description: CAS Number: 12080-32-9
MDL Number: MFCD00012413
Molecular Formula: C8H12Cl2Pt
Molecular Weight: 374.17
Form: Crystal
Color: Very Pale Yellow
Melting point (°C): 285

SDS Certificates

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