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Catalog Number: (76520-118)
Supplier: VWR International
Description: Includes an extra wire frame shelf made to fit VWR® Standard Series Laboratory units.


Catalog Number: (10748-676)
Supplier: Prosci
Description: Presenilin1 Antibody: Presenilin1 was initially identified a marker of susceptibility to early-onset Alzheimer's disease. In addition to PEN2, nicastrin and APH-1, Presenilin1 forms the gamma-secretase protein complex, a membrane-bound aspartyl protease that can cleave certain proteins at peptide bonds buried within the hydrophobic environment of the lipid bilayer. This cleavage is responsible for a key step in signaling from several cell-surface receptors and is thought to be required for the generation of the neurotoxic amyloid peptides that are central to the pathogenesis of Alzheimer's disease. Like the tumor necrosis factor-alpha-converting enzyme (TACE) and the beta-site cleavage enzyme (BACE) protease families, gamma-secretase will cleave the amyloid precursor protein (APP), but within the intramembrane region of APP, resulting in either the non-toxic p3 (from the alpha and gamma cleavage site) or the toxic Abeta amyloid peptide (from the beta and gamma cleavage site). It is thought that accumulation of the Abeta peptide is the precursor to Alzheimer's disease. Multiple isoforms of presenilin1 are known to exist. This antibody has no cross-reactivity to presenilin2.


Supplier: VWR International
Description: Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation. IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses.

New Product

Catalog Number: (76520-060)
Supplier: VWR International
Description: Includes an extra wire frame shelf made to fit VWR® Performance and Plus Series Chromatography units.


Catalog Number: (76520-098)
Supplier: VWR International
Description: Includes an extra wire frame shelf made to fit VWR® Performance and Plus Series Laboratory units.


Supplier: VWR International
Description: Swing door, upright laboratory chromatography refrigerators maintain an average temperature of 2 to 8 °C (35.6 to 46.4 °F)

UL Listed Environmentally Preferable cUL Listed Product available on GSA Advantage®

Catalog Number: (76520-078)
Supplier: VWR International
Description: Includes an extra wire frame shelf made to fit VWR® Standard Series Chromatography units.


Supplier: VWR International
Description: Interleukin 17AF (IL-17AF) is a heterodimer that is composed of the interleukin 17A (IL-17A) and interleukin 17F (IL-17F) members of the IL-17 family of cytokines. IL-17AF is produced by T helper 17 cells (Th17) following interleukin 23 (IL-23) stimulation. IL-17AF signals through the IL-17RA/IL-17RC receptor complex and functions to regulate inflammatory responses. IL-17AF induces chemokine and airway neutrophilia production, similar in function to IL-17A and IL-17F homodimers. In regard to these functions, IL-17AF is less active than the IL-17A homodimer and shows greater activity than the IL-17F homodimer. Human and rat IL-17AF are active on mouse cells.

New Product

Supplier: TCI America
Description: CAS Number: 75804-28-3
Molecular Formula: C6H16N2
Molecular Weight: 189.12
Purity/Analysis Method: >98.0% (N,T)
Form: Crystal
Supplier: VWR International
Description: The VWR® Autoclaves are ideal for sterilization of media, liquid, glassware, plasticware and other common research laboratory items. Available in 8, 18, 23 and 28 L chamber volumes, the range meets small to medium size applications in a space saving benchtop design.

Supplier: MilliporeSigma
Description: 2,3-Dimethylaniline, CAS Number: 87-59-2, Synonyms: vic.-o-Xylidine, Chemical formula: 2,3-(CH3)2C6H3NH2, for synthesis.

SDS

Supplier: MilliporeSigma
Description: 2,3-Butanediol, CAS Number: 513-85-9, Synonyms: 2,3-Butylene glycol, Chemical formula: CH3CH(OH)CH(OH)CH3, for synthesis.

SDS

Supplier: Thermo Scientific Chemicals
Description: 2,3-Dimethylanisole 97%
Supplier: Thermo Scientific Chemicals
Description: 2,3-Dichlorobenzonitrile 98%
Supplier: VWR International
Description: Dippers feature a 60 cm (23<sup>5</sup>/<sub>8</sub>") long steel shaft encapsulated in PTFE for rigidity.

Supplier: Thermo Scientific Chemicals
Description: (2R,3R)-(-)-2,3-Butanediol 98%
Inquire for Price
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


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