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Product Image-89161-126

ADAM Substrate

Catalog Number: (89161-126)
Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for ADAM8 (kcat/Km = 1.0 x 105 M-1s-1), ADAM10 (6.2 x 103), ADAM12 (2.8 x 105), TACE (TNF-α converting enzyme, ADAM17) (4.3 x 105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485nm, Em.: 530nm. This substrate is useful for inhibitor screening and kinetic analysis.
Image Unavailable-76219-114

(S,S,S)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine ≥98.0% (by HPLC)

Supplier: TCI America
Description: (S,S,S)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl)bis(1-phenylethyl)amine, Purity: >98.0%(HPLC), CAS: 209482-27-9, MF: C36H30NO2P, MW: 539.61, Form: Crystal- Powder, Size: 1G

Image Unavailable-TCR0122-200MG

RuCl[(S,S)-Fsdpen](p-cymene) ≥90% (by NMR)

Supplier: TCI America
Description: CAS Number: 1026995-72-1
MDL Number: MFCD12545954
Molecular Formula: C30H28ClF5N2O2RuS
Molecular Weight: 712.14
Purity/Analysis Method: >90% (NMR)
Form: Crystal
Color: Yellow
Melting point (°C): 244
Flash Point (°C): 100
Specific rotation [a]20/D: 48 deg (C=0.1, CHCl3)

SDS

Image Unavailable-CAAAJ60426-14

Quinidine sulfate Dihydrate ≥98%

Supplier: Thermo Scientific Chemicals
Description: A sodium channel blocker, and to a lesser extent also blocks potassium channels

Certificates

Product Image-10044-546

ProSwift WAX-1S Protein Columns, Thermo Scientific

Catalog Number: (10044-546)
Supplier: Thermo Scientific
Description: Fast ion-exchange separation and protein purification is possible using the Thermo Scientific™ ProSwift ion exchange (IEX) columns.
Product Image-89160-974

Matrix Metalloproteinase Substrate (Fluorescent)

Catalog Number: (89160-974)
Supplier: Enzo Life Sciences
Description: Fluorogenic substrate for several matrix metalloproteinases (MMPs). It is cleaved by MMP-1 (kcat/Km=3.3x10M-1s-1), MMP-2 (kcat/Km=5.8x10), MMP-3 (kcat/Km=2.2x10), MMP-7 (kcat/Km=1.2x10), MMP-8, MMP-9 (kcat/Km=6.9x10), and MMP-26 (kcat/Km=4.9x10) Ex/Em=280nm/346nm, although 283/350,360 are also appropriate. Fluorescence at 346 nm by tryptophan occurs once cleavage separates it from the quenching aromatic Dnp moiety. MMPs cleave this peptide between Gly-Leu.
Image Unavailable-CA11006-674

Marimastat ≥98% (by NMR), Calbiochem®, Sigma-Aldrich®

Catalog Number: (CA11006-674)
Supplier: MilliporeSigma
Description: An orally active peptidyl hydroxamate-based broad-spectrum MMP inhibitor that targets both the substrate binding site and the active-site Zn2+.

SDS Certificates


Image Unavailable-CAAAJ61071-MC

Castanospermine 99%

Supplier: Thermo Scientific Chemicals
Description: Potent alpha and beta-glucosidase inhibitor.

Certificates

Image Unavailable-76219-542

(S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol ≥98.0% (by GC)

Supplier: TCI America
Description: (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol, Purity:>98%, CAS: 225920-05-8, MF: C10H8F6O, MW: 258.16, Synonyms: (S)-3,5-Bis(trifluoromethyl)-A-methylbenzyl Alcohol, (S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl Alcohol, Form: Crystal-Powder, Size: 5G

Image Unavailable-CA80053-228

MnTMPyP

Catalog Number: (CA80053-228)
Supplier: MilliporeSigma
Description: Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O2- (rate constant ~4x107 M-1s-1) even in the presence of excess EDTA. Can substitute for SOD in mutants of E. coli lacking this enzyme. MnTMPyP acts in vivo as an NADPH/GSH:O2- oxidoreductase rather than as an SOD mimetic. Also an efficient peroxynitrite reductase when redox coupled with biological antioxidants.

Certificates


Image Unavailable-CA8.02304.0025

(-)-Quinine for synthesis, for resolution of racemates, Sigma-Aldrich®

Catalog Number: (CA8.02304.0025)
Supplier: MilliporeSigma
Description: (-)-Quinine, CAS number:130-95-0, Synonyms:6-Methoxy-alpha-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol, Application:for resolution of racemates for synthesis

SDS Certificates


Product Image-10044-548

ProSwift WCX-1S Protein Columns, Thermo Scientific

Catalog Number: (10044-548)
Supplier: Thermo Scientific
Description: Fast ion-exchange separation and protein purification is possible using the Thermo Scientific™ ProSwift ion exchange (IEX) columns.
Product Image-10044-588

ProSwift SCX -1S Protein Columns, Thermo Scientific

Catalog Number: (10044-588)
Supplier: Thermo Scientific
Description: Fast ion-exchange separation and protein purification is possible using the Thermo Scientific™ ProSwift ion exchange (IEX) columns.
Image Unavailable-CA80050-660

Calpain Inhibitor IV (Z-LLY-FMK), Calbiochem®

Catalog Number: (CA80050-660)
Supplier: MilliporeSigma
Description: A potent, cell-permeable, and irreversible inhibitor of calpain II (k2=28,900 M-1s-1)

Certificates


Image Unavailable-CA80057-568

(±)-Taxifolin, hydrate ≥95% (by HPLC), Calbiochem®, Sigma-Aldrich®

Catalog Number: (CA80057-568)
Supplier: MilliporeSigma
Description: An antioxidant flavonoid that scavenges superoxide anion (1.5x105 M-1s-1) and suppresses the cytotoxicity of superoxide ions and hydrogen peroxide in Chinese hamster V79 cells.

Certificates


Image Unavailable-10088-394

Anti-HOMER1 Rabbit Polyclonal Antibody

Catalog Number: (10088-394)
Supplier: Proteintech
Description: Human HOMER1, also named as SYN47, belongs to the Homer family. Human HOMER1 has some isoforms: HOMER1a, HOMER1b, HOMER1c, HOMER1e and HOMER1h. Mouse Homer1 also named as Vesl-1 and it has some isoforms: Vesl-1l, Vesl-1m, Vesl-1s, Homer1b, and Homer1d. HOMER1 is a postsynaptic density scaffolding protein. It is a neuronal immediate-early gene (IEG) that is enriched at excitatory synapses and binds mGluRs. In WB, the MW of HOMER1 is about 46-50kd, 40-43kd and 20-26kd.
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