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Supplier: Biotium

Description: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Supplier: Biotium

Description: CD68 Monoclonal antibody, Clone: C68/684, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG1, Conjugate: CF568, Immunogen: Recom human CD68 protein, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 100uL

Catalog Number: (75915-776)

Supplier: Biotium

Description: CD66 Monoclonal antibody, Clone: COL-1, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: BSA-free, Immunogen: Human colon carcinoma extract, Synonyms: CEACAM5, Application: IF, IHC, Size: 50 uL

Supplier: Biotium

Description: CD68 Monoclonal antibody, Clone: C68/684, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG1, Conjugate: purified, Immunogen: Recom human CD68 protein, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 500 uL

Supplier: Biotium

Description: CD66 Monoclonal antibody, Clone: COL-1 + CEA31 + C66/261, Host: Mouse, Species reactivity: Human, Isotype: IgG1, K, Conjugate: CF405S, Immunogen: Recom full-length human CEA, Synonyms: CEACAM5, Application: IF, Size: 500 uL

Supplier: Biotium

Description: CD68 Monoclonal antibody, Clone: C68/684 + KP1, Host: Mouse, Species reactivity: Human, Monkey, Cat, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Subcellular fraction, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 500 uL

Catalog Number: (75915-896)

Supplier: Biotium

Description: CD68 Monoclonal antibody, Clone: C68/684 + KP1, Host: Mouse, Species reactivity: Human, Monkey, Cat, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Subcellular fraction, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 50 uL

Supplier: Biotium

Description: This MAb recognizes cytokeratin 4, 5, 6, 8, 10, 13, and 18. This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Supplier: Biotium

Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

Description: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Supplier: Biotium

Description: Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast.

Supplier: Biotium

Description: This antibody recognizes cytokeratin 10 (56.5 kDa) and cytokeratin 13 (53 kDa) in Western blotting. It recognizes only cytokeratin 13 in formalin-fixed, paraffin-embedded tissue sections. It does not react with cytokeratin 10 positive, cytokeratin 13 negative epithelia such as epidermis. However, on frozen sections this MAb serves as differentiation-related marker of all stratified epithelia; it stains all suprabasal cells in both cornifying and non-cornifying stratified epithelia and more differentiated cells of squamous carcinomas.

Supplier: Biotium

Description: Cytokeratin 17 Monoclonal antibody, Clone: E3, Host: Mouse, Species reactivity: Goat, Pig, Cow, Rat, Human, Isotype: IgG2b, kappa, Conjugate: purified, Immunogen: The cytoskeletal fraction, Synonyms: K17, KRT17, PCHC1, Application: IF, Size: 500 uL

Supplier: Biotium

Description: CD63 Monoclonal antibody, Clone: NKI-C3, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Smooth plasma membrane fraction of MeWo cells, Application: IF, Immunohistology (formalin), Western, FC, Size: 100uL

Supplier: Biotium

Description: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Supplier: Biotium

Description: CD63 Monoclonal antibody, Clone: NKI-C3, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Smooth plasma membrane fraction of MeWo cells, Application: IF, Immunohistology (formalin), Western, FC, Size: 100uL