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Catalog Number: (89166-086)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG2b


Catalog Number: (89166-084)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG1


Catalog Number: (89163-072)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89154-374)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG2a


Catalog Number: (89153-388)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG2a


Catalog Number: (89154-482)
Supplier: Enzo Life Sciences
Description: Capases are a highly conserved family of cysteine proteases and are synthesized as inactive zymogens, which are cleaved at Asp-x sites during apoptosis, generating large and small subunits that heterodimerize to form the active enzyme. Caspase-1 is a member of the ICE/CED-3 family of caspases and is detected in the pro-form as a protein of 45 kDa.
Caspase-1 generates the bioactive form of the pro-inflammatory cytokine IL-1β from its biologically inactive precursor. Overexpression of caspase-1 in cells induces apoptosis, which can be inhibited by cytokine response modifier A (CrmA). Caspase-1 mRNA is predominantly expressed in the spleen and lung and to a lesser extent in skeletal muscle, kidney, testis and heart and within these tissues macrophages preferentially express caspase-1. Caspase-1 deficient mice have no gross abnormalities, however, macrophages from caspase-1-deficient mice are defective in IL-β processing and release.


Catalog Number: (89154-304)
Supplier: Enzo Life Sciences
Description: Host: Rat, Isotype: IgG1


Catalog Number: (89158-676)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG1

Supplier: Enzo Life Sciences
Description: Ubiquitin modification of cellular proteins has been shown to be involved with a wide range of biochemical processes including proteasomal degradation, signal transduction, DNA repair, endocytosis and autophagy.

Supplier: Enzo Life Sciences
Description: Host: Rabbit

Catalog Number: (89162-104)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89153-534)
Supplier: Enzo Life Sciences
Description: The ryanodine receptor (RyR) is the channel responsible for the release of calcium from the sarcoplasmic reticulum (SR) in muscle cells and also plays a role in calcium regulation in non-muscle cells. The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains; the remainder of the protein, termed the "foot" region is located in the cytoplasm between the T-tubule and the SR. The mammalian RyR is the product of three different genes: RyR-1, which is expressed predominantly in skeletal muscle and areas of the brain, RyR-2, which is expressed predominantly in the heart muscle but also found in the stomach, endothelial cells and diffuse areas of the brain, and RyR-3 which is found in smooth muscle and the brain (striatum, thalamus and hippocampus).


Catalog Number: (89153-160)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG1


Catalog Number: (89145-494)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89145-496)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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