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Catalog Number: (89146-314)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89162-698)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Supplier: Enzo Life Sciences
Description: Host: Rat, Isotype: IgG2a

Catalog Number: (89146-246)
Supplier: Enzo Life Sciences
Description: VASP (vasodilator stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. Phosphorylation of VASP at Ser-157 causes a mobility shift in SDS gel electrophoresis from 46 to 50 kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity. VASP is the founding member of the Ena-VASP protein family, comprising the Drosophila protein Enabled (Ena), its mouse homologue Mena (mammalian Enabled), and mouse EVL (Ena-VASP-like protein). With these proteins VASP shares a conserved overall domain organization:
a) the conserved N-terminal Ena-VASP homology domain 1 (EVH1), which mediates binding to a proline-rich motif
b) a more divergent proline-rich central domain (which is responsible for profilin binding)
c) a conserved C-terminal EVH2 domain.

VASP is expressed in a variety of mammalian cell types and tissues. In cultured cells, VASP is associated with focal adhesions, cell-cell contacts, microfilaments, and highly dynamic membrane regions. From in vitro binding data VASP has been suggested to link profilin to zyxin, vinculin, and the Listeria spp. surface protein ActA, respectively. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation and the actin-dependent motility of intracellular bacterial pathogens.


Catalog Number: (89155-246)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG1


Catalog Number: (89155-272)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG3


Catalog Number: (89141-802)
Supplier: Enzo Life Sciences
Description: Osteoprotegerin (OPG) is a secreted glycoprotein belonging to the TNF receptor (TNF-R) superfamily that functions as a decoy receptor for RANK-Ligand (RANKL/OPGL). Unlike other TNF-Rs, OPG lacks a membrane-anchoring hydrophobic domain and lacks any apparent cell-associated signaling capability. OPG secreted by osteoblasts competes with RANK (expressed on osteoblast precursors) for binding to RANKL, blocking osteoclastogenesis and increasing bone density.


Catalog Number: (89154-058)
Supplier: Enzo Life Sciences
Description: Host: Rat, Isotype: IgG1


Catalog Number: (89146-096)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89146-108)
Supplier: Enzo Life Sciences
Description: Host: Rabbit


Catalog Number: (89153-096)
Supplier: Enzo Life Sciences
Description: TLR9 ligand.


Catalog Number: (89158-988)
Supplier: Enzo Life Sciences
Description: HDAC inhibitor


Supplier: Enzo Life Sciences
Description: Inhibitor of caspase-6, -8 and -10

Catalog Number: (89164-092)
Supplier: Enzo Life Sciences
Description: Produced in E. coli. Full length human CDC25B.


Supplier: Enzo Life Sciences
Description: Quick, easy kit for purifying DNA from PCR, gels and labeling reactions for a variety of downstream applications.

SDS

Catalog Number: (89142-848)
Supplier: Enzo Life Sciences
Description: NOS inhibitor.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
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