Phosphoramidon

Supplier: Enzo Life Sciences

BML-PI111-0005 BML-PI111-0025
89161-592EA 336.54 CAD
89161-592 89161-594
Phosphoramidon
Proteins and Peptides

Neprilysin inhibitor


Inhibits neutral endopeptidase 24.11 (NEP, neprilysin; EC 3.4.24.11) (Ki=2nM), a cell surface zinc metalloprotease which cleaves bioactive peptides such as bradykinin, neurotensin, and enkephalin. Also inhibits neprilysin 2 (Ki~2nM). Potent inhibitor of endothelin-converting enzyme (ECE) (IC50=0.68μM).

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