You Searched For: trans-4-tert-Butylcyclohexanecarboxylic+acid


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Catalog Number: (10424-254)
Supplier: Bioss
Description: Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.


Supplier: Bachem Americas
Description: Sequence: 11-(Boc-amino)-undecanoic acid

Catalog Number: (10084-638)
Supplier: Proteintech
Description: Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.


Catalog Number: (TCB1630-005G)
Supplier: TCI America
Description: CAS Number: 15260-10-3
MDL Number: MFCD00066062
Molecular Formula: C16H23NO5
Molecular Weight: 309.36
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 116
Specific rotation [a]20/D: 16.5 deg (C=1, MeOH)

SDS


Catalog Number: (TCB5141-200MG)
Supplier: TCI America
Description: N-(Tert-Butoxycarbonyl)-2,2'-(Ethylenedioxy)Diethylamine, Purity: >97.0%(HPLC), Cas no: 153086-78-3, Molecular formula : C11H24N2O4, Molecular weight : 248.32, Synonyms: N-Boc-3,6-dioxa-1,8-octanediamine, Size: 200MG


Supplier: Bachem Americas
Description: Sequence: Fmoc-D-Ser(BSi)-OH

Supplier: Bachem Americas
Description: Sequence: Fmoc-N-Me-Lys(Boc)-OH

Supplier: TCI America
Description: CAS Number: 37784-17-1
MDL Number: MFCD00063226
Molecular Formula: C10H17NO4
Molecular Weight: 215.25
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 135
Specific rotation [a]20/D: 60 deg (C=2, AcOH)
Catalog Number: (10433-030)
Supplier: Bioss
Description: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)


Supplier: Bachem Americas
Description: Boc-Oic-OH, (2S, 3aS, 7aS)-1-Boc-octahydro-1H-indole-2-carboxylic acid 1g, Cas number 109523-13-9, Storage Condition: -20 +/- 5 degree C

Catalog Number: (10347-790)
Supplier: Bioss
Description: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.


Catalog Number: (10347-788)
Supplier: Bioss
Description: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.


Supplier: TCI America
Description: CAS Number: 15761-38-3
MDL Number: MFCD00037225
Molecular Formula: C8H15NO4
Molecular Weight: 189.21
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 83
Specific rotation [a]20/D: -25.5 deg (C=2, AcOH)
Supplier: Bachem Americas
Description: Sequence: Boc-β-tBu-Ala-OH

Catalog Number: (10669-004)
Supplier: Bioss
Description: IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.


Catalog Number: (10347-784)
Supplier: Bioss
Description: The ankyrin repeat and SOCS box containing (ASB) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.


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