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Product Image-10097-020

Anti-VPS35 Rabbit Polyclonal Antibody

Catalog Number: (10097-020)
Supplier: Proteintech
Description: VPS35 protein belongs to a group of vacuolar protein sorting (VPS) proteins, which ensure the proper delivery of organelle-specific proteins in eukaryotic cells. VPS35 is the core of a multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. Vps35 serves as the core of the multimeric complex by binding directly to Vps26 and Vps29 and SNX1. Northern blot analyses in 16 tissues showed that one transcript of Vps35 with a size of 3.6 kb was highly expressed in brain, heart, testis, ovary, small intestine, spleen, skeletal muscle, and placenta and expressed at moderate or low levels in other tissues. Another transcript of Vps35, a message of 3.0 kb, was also expressed with proportionally lower levels than the 3.6-kb transcript in all the tissues except that the 3.0-kb transcript was not detected in brain. Human Vps35 is mapped at 16q13-q21.
Image Unavailable-77665-078

Rodent Brain Matrices, Acrylic

Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: Using a WPI brain matrix, you can get thin and uniform brain slices, which is crucial for histological analysis, immunohistochemistry, molecular biology, and more. This consistency is essential for accurate comparisons between different brains and experimental conditions. These WPI rodent brain matrices are made of acrylic, a durable material. They have precision-cut channels or slots that hold the brain in place during slicing. Choose your brain matrix based on your species (mouse or rat) and the size of the animal.

New Product

Product Image-89417-192

Anti-GOLPH3 Rabbit Polyclonal Antibody

Catalog Number: (89417-192)
Supplier: Prosci
Description: GOLPH3 Antibody: GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.
Product Image-16002-788

Flow Meter, Nitrogen, with Metering Valve, Chemglass

Supplier: Chemglass
Description: Precision machined clear acrylic Nitrogen flowmeter with brass metering valve and Buna-N seals for use with Chemglass process reactors.

Small Business Enterprise

Product Image-100493-150

Nitrogen Purge Cabinet, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: Acrylic, ethylene propylene, and Type 316 stainless steel welded parts

Minority or Woman-Owned Business Enterprise

Product Image-CA37000-548

Nunc™ Polyolefin Acrylate Sealing Tape, Thermo Scientific

Catalog Number: (CA37000-548)
Supplier: Thermo Fisher Scientific
Description: The polyolefin acrylate sealing tapes minimize evaporation and protect samples from contamination and spilling.

Certificates


Image Unavailable-CAAAB22125-06

2-Pentylpyridine 98%

Supplier: Thermo Scientific Chemicals
Description: 2-Pentylpyridine 98%

Certificates

Product Image-CA55607-374

Dust Mask Dispenser, Brady®

Catalog Number: (CA55607-374)
Supplier: Brady Worldwide
Description: Our Dust Mask Dispensers is made of durable clear acrylic and can be table or wall mounted for easy access.
Product Image-76293-222

SealPlate® RollMate™, Pre-Secored Sheets on a Roll with Dispenser, Non-Sterile, Excel Scientific

Catalog Number: (76293-222)
Supplier: VWR International
Description: The SealMate SealPlate Starter Kit features a re-usable dispenser and two sterile rolls of perforated film.

Certificates


Product Image-470312-386

VersaLoupe™ LH-30 Magnifier, Carson

Catalog Number: (470312-386)
Supplier: CARSON OPTICAL
Description: Accurate and easy to focus.
Product Image-13197-460

SP Bel-Art Inhalation Narcosis Chamber, Bel-Art Products, a part of SP

Catalog Number: (13197-460)
Supplier: Bel-Art Products, a Part of SP
Description: A clear acrylic, hinged cover permits observation of small animals during anesthetizing.
Image Unavailable-H-3154.0025BA

H-Tyr-Arg-Gly-Asp-Ser-OH Trifluoroacetate

Supplier: Bachem Americas
Description: PEG acrylate-based hydrogels have been modified with the RGD peptide YRGDS to improve their biocompatibility. YRGDS can be radioiodinated.

Image Unavailable-75927-686

Anti-GLG1 Mouse Monoclonal Antibody (Biotin) [clone: GLG1/970]

Supplier: Biotium
Description: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

Product Image-470148-826

Complete Ripple Tank Apparatus

Catalog Number: (470148-826)
Supplier: Shiv Dial Sud & Sons
Description: This ripple tank is transparent, acrylic plastic and supported in a sturdy plastic frame.
Product Image-470002-754

Oak-Framed Demonstration Mirror

Catalog Number: (470002-754)
Supplier: Diversified Woodcrafts
Description: The shatter resistant mirror is an acrylic mirror enclosed in a solid oak frame with a natural transparent finish.

Environmentally Preferable


Image Unavailable-75927-180

Anti-GLG1 Mouse Monoclonal Antibody [clone: GLG1/970]

Supplier: Biotium
Description: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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