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VWR® Media Bottles, Square, PETG

Supplier: VWR International
Description: These sterile media bottles are manufactured from Eastar™ PETG, the resin of choice for single use labware.

Certificates

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Avantor Sterile Polycarbonate Single-Use Flask Assemblies, Avantor Fluid Handling

Supplier: VWR International
Description: Sterile polycarbonate flasks with weldable tubing provide the maximum amount of flexibility and reliability.

Certificates

Image Unavailable-76491-706

VWR® Sterile Alliance Sleeves, Made in USA

Supplier: VWR International
Description: VWR® Made in USA sterile sleeves are an ideal option for single-use needs. Made with the specially formulated alliance breathable microporous fabric.

Certificates

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VWR® ETO Sterilized Alliance Sleeves, Made in USA

Catalog Number: (76470-704)
Supplier: VWR International
Description: VWR® Made in USA Sterile Sleeves are an ideal option for single-use needs. Made with the specially formulated Alliance breathable microporous fabric.
Product Image-10754-976

VWR® Disposable Long Sleeve Scrub Shirts

Supplier: VWR International
Description: VWR® Disposable Scrub Shirts are an ideal option for single-use needs.

Certificates

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VWR® SMS Coveralls, Made in USA

Supplier: VWR International
Description: VWR® Made in USA SMS Coveralls are an ideal option for single-use needs.

Product Image-60941-126

VWR® Aluminium Foil Seals for PCR and Storage (96- and 384-Well Plates)

Supplier: VWR International
Description: Aluminium foils, 75.7 µm thick, for use with 96- or 384-well plates. Fit inside the rim of raised rim plates. These foils have one partial-width end tab. Available non sterile only.

Certificates

Image Unavailable-76491-690

VWR® Single Channel Electronic Timer with Triple Alarms and Certificate of Calibration

Catalog Number: (76491-690)
Supplier: VWR International
Description: Choice of vibration, sound, and/or light alarms make this timer ideal for use in high noise locations.
Product Image-MFLX31201-66

Masterflex® Single-Use Sanitary Gaskets, TPE, Avantor®

Supplier: VWR International
Description: Ensure a tight seal in your sanitary fluid line.

Certificates 3A Sanitary approval

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Orion™ Sure-Flow® Reference Electrode, Ag/AgCl Single Junction Half-Cell, Thermo Scientific

Catalog Number: (34107-923)
Supplier: Thermo Fisher Scientific
Description: This reference half-cell electrode helps to precisely measure with ion-selective electrodes. Ideal for ISE determinations and routine pH measurements with Orion™ 910100 electrodes.
Product Image-76491-704

VWR® SMS Shoecovers, Made in USA

Supplier: VWR International
Description: VWR® Made in USA SMS Shoecovers are an ideal option for single-use needs. Formulated with a 3-layer SMS material.

Image Unavailable-10451-514

Anti-XPC Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10451-514)
Supplier: Bioss
Description: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Image Unavailable-10451-516

Anti-XPC Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10451-516)
Supplier: Bioss
Description: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
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VWR® Signature™ Shoe Covers made with DuPont™ Tyvek® IsoClean® Material

Supplier: VWR International
Description: Shoe covers are manufactured using a unique flash spinning process that creates an excellent barrier against nonhazardous liquids and microorganisms as well as dry particles down to 0.5µm.

Certificates

Image Unavailable-10495-516

Anti-INIP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10495-516)
Supplier: Bioss
Description: The SOSS (Sensor of single-strand DNA) complex consists of multiple proteins that promote DNA repair and G2/M checkpoint downstream of the MRN (Mre11, Rad50 and Nbs1) complex. The complex is composed of SSBP1, INTS3 and C9orf80. Specifically, the SOSS complex binds to ssDNA at DNA lesions that influences diverse endpoints in the cellular DNA damage response. The complex is required for efficient homologous recombination-dependent repair of double-stranded breaks and ATM-dependent signaling pathways. C9orf80, also known as SOSS complex subunit C and Single-stranded DNA-binding protein-interacting protein 1 (SSBIP1), is a 104 amino acid nuclear protein that is a component of the SOSS complex. Upon DNA damage, C9orf80 along with other components of the SOSS complex migrate to the nucleus. There are two isoforms of C9orf80 that are produced as a result of alternative splicing events.
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VWR® Basic Industrial Lab Coats

Supplier: VWR International
Description: VWR® Basic protection industrial lab coats are a lightweight, single-use protective option available in a variety of colors and sizes.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
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VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
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