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Catalog Number: (10489-882)
Supplier: Bioss
Description: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32.


Catalog Number: (10107-724)
Supplier: Prosci
Description: ZNF527 contains 1KRAB domain and 12 C2H2-type zinc-fingers. It belongs to the kruppel C2H2-type zinc finger protein family and may be involved in transcriptional regulation.


Catalog Number: (10667-894)
Supplier: Bioss
Description: ZNRF4 contains 1 PA (protease associated) domain and 1 RING-type zinc finger.


Catalog Number: (10751-170)
Supplier: Prosci
Description: ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.


Catalog Number: (10101-712)
Supplier: Prosci
Description: ZFAND3 contains 1 A20-type zinc finger and 1 AN1-type zinc finger. The exact function of ZFAND3 remains unknown.


Catalog Number: (10107-120)
Supplier: Prosci
Description: ZNF282 contains 1 KRAB domain and 5 C2H2-type zinc fingers. It belongs to the krueppel C2H2-type zinc-finger protein family and binds to the U5 repressive element (U5RE) of the human T cell leukemia virus type I long terminal repeat.


Catalog Number: (10099-560)
Supplier: Prosci
Description: ZNF263 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 9 C2H2-type zinc fingers, 1 KRAB domain and 1 SCAN box domain. ZNF263 might play an important role in basic cellular processes as a transcriptional repressor.


Catalog Number: (10667-908)
Supplier: Bioss
Description: ZNRF4 contains 1 PA (protease associated) domain and 1 RING-type zinc finger.


Catalog Number: (10664-668)
Supplier: Bioss
Description: Involved in accumulation of zinc in synaptic vesicles.


Catalog Number: (10670-206)
Supplier: Bioss
Description: The ring finger is a specialized type of zinc finger of 40 to 60 residues that binds two atoms of zinc and mediates protein-protein interactions. There are five known isoforms of RNF170.


Catalog Number: (10670-210)
Supplier: Bioss
Description: The ring finger is a specialized type of zinc finger of 40 to 60 residues that binds two atoms of zinc and mediates protein-protein interactions. There are five known isoforms of RNF170.


Catalog Number: (10109-206)
Supplier: Prosci
Description: Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters.


Catalog Number: (10111-740)
Supplier: Prosci
Description: ZNF417 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 13 C2H2-type zinc fingers and 1 KRAB domain. ZNF417 may be involved in transcriptional regulation.


Catalog Number: (10111-716)
Supplier: Prosci
Description: ZNF333 belongs to the krueppel C2H2-type zinc-finger protein family. Itcontains 10 C2H2-type zinc fingers and 2 KRAB domains. ZNF333 may be involved in transcriptional regulation.


Catalog Number: (10111-724)
Supplier: Prosci
Description: ZIM3 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 11 C2H2-type zinc fingers and 1 KRAB domain. ZIM3 may be involved in transcriptional regulation.


Catalog Number: (76110-028)
Supplier: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZSWIM3 (Zinc finger SWIM domain-containing protein 3) is a 696 amino acid protein that contains one SWIM-type zinc finger. SWIM domains are found in a variety of eukaryotic and prokaryotic proteins and are thought to be critical for certain ubiquitination reactions. The gene encoding ZSWIM3 maps to human chromosome 20, which contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.


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