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Catalog Number: (10667-934)
Supplier: Bioss
Description: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF141 (ring finger protein 141), also known as ZFP26 or ZNF230, is a 230 amino acid protein that contains one RING-type zinc finger. Expressed as two isoforms (isoform 1 and isoform 2) due to alternative splicing events, RNF141 is thought to function as a transcription factor during spermatogenesis. While isoform 2 is expressed in brain, heart, pancreas, kidney and skeletal muscle, isoform 1 is expressed primarily in testis, suggesting that isoform 1 functions during spermatogenesis. In addition, RNF141 is not expressed in azoospermic (infertile) men, further implicating an important role for RNF141 in testis development and male fertility.


Catalog Number: (CA97013-290)
Supplier: PerkinElmer
Description: Multi-Element Lumina™ hollow cathode lamp (HCL) for the detection of elemental Calcium (Ca) and Zinc (Zn). Series N30502XX Lumina™ 50 mm (2") diameter multi-element lamps are designed to be used with PinAAcle™ and AAnalyst™ Atomic Absorption spectrometer series of instruments.


Catalog Number: (10751-102)
Supplier: Prosci
Description: ZNF346 Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.


Catalog Number: (CA1.14688.0001)
Supplier: MilliporeSigma
Description: Crack Set 10C for the digestion of lead, cadmium, iron, copper, nickel, phosphorus (total) and zinc 25 digestions Spectroquant*

SDS


Catalog Number: (10793-342)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to ZNHIT6 (zinc finger, HIT-type containing 6)


Catalog Number: (10669-740)
Supplier: Bioss
Description: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF23 (RING finger protein 23), also known as tripartite motif-containing protein 39 (TRIM39) or testis-abundant finger protein, is a 518 amino acid protein belonging to the TRIM/RBCC family that is known to interact with MOAP1. Ubiquitously expressed and existing as two alternatively spliced isoforms, RNF23 is found at highest levels in spleen, testis, brain, kidney, liver, heart and skeletal muscle. RNF23 typically localizes to cytosol but shifts to mitochondria upon co-localization with MOAP1, a short-lived, pro-apoptotic protein which RNF23 prevents from becoming poly-ubiquitinated and degraded, thereby facilitating apoptosis. RNF23 contains one B box-type zinc finger, a B30.2/SPRY domain and a single RING-type zinc finger.


Catalog Number: (10667-916)
Supplier: Bioss
Description: ZNRF4 contains 1 PA (protease associated) domain and 1 RING-type zinc finger.


Catalog Number: (10463-334)
Supplier: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.


Catalog Number: (21573-800)
Supplier: VWR International
Description: The Talon® Double Jaw Utility Clamp holds two sizes of object with care and features a medium and a large two-prong clamp that swivel 360° in one plane.

Product available on GSA Advantage®


Catalog Number: (10463-312)
Supplier: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.


Catalog Number: (89350-304)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to GLI3 (GLI family zinc finger 3)


Catalog Number: (76116-648)
Supplier: Bioss
Description: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.


Catalog Number: (10670-238)
Supplier: Bioss
Description: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF185 (ring finger protein 185), also known as FLJ38628, is a 192 amino acid multi-pass membrane protein containing one RING-type zinc finger. Two RNF185 isoforms exist as a result of alternative splicing, and the gene encoding RNF185 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.


Catalog Number: (89416-582)
Supplier: Prosci
Description: EVER2 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.


Catalog Number: (10664-664)
Supplier: Bioss
Description: Involved in accumulation of zinc in synaptic vesicles.


Catalog Number: (10751-212)
Supplier: Prosci
Description: ZMYM4 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-gamma;-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.


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