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Staurosporine

Catalog Number: (89138-114)
Supplier: Biotium
Description: Staurosporine is a potent apoptosis inducer.
Product Image-89149-818

Staurosporine ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: Apoptosis inducer

Image Unavailable-CAAAJ62837-MCR

Staurosporine ≥99%

Supplier: Thermo Scientific Chemicals
Description: Broad spectrum protein kinase inhibitor

Certificates

Image Unavailable-CA80057-526

Staurosporine (from Streptomyces species), Sigma-Aldrich®

Supplier: MilliporeSigma
Description: A potent cell-permeable broad spectrum inhibitor of protein kinases

Certificates

Product Image-10782-636

Anti-SNCB Sheep Polyclonal Antibody

Catalog Number: (10782-636)
Supplier: Biosensis
Description: Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects nerurons from staurosporine and 6 hydroxy dopamine -stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1).
Product Image-10782-354

Anti-SNCB Rabbit Polyclonal Antibody

Catalog Number: (10782-354)
Supplier: Biosensis
Description: Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects nerurons from staurosporine and 6 hydroxy dopamine -stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1).
Image Unavailable-CA80017-392

Midostaurin ≥98% (by HPLC), Calbiochem®

Catalog Number: (CA80017-392)
Supplier: MilliporeSigma
Description: CGP 41 251, N-Benzoylstaurosporine

SDS Certificates


Product Image-10782-752

Anti-SNCB Sheep Polyclonal Antibody

Catalog Number: (10782-752)
Supplier: Biosensis
Description: Beta-synuclein is a non-amyloid component of senile plaques found in Alzheimer disease. It could act as a regulator of SNCA aggregation. It protects neurons from staurosporine and 6 hydroxy dopamine -stimulated capspase activation in a p53-dependent manner. It localises to the cytoplasm and it is predominantly expressed in the brain where it is most concentrated in presynaptic nerve terminals. This protein is phosphorylated. This protein is also associated with the disease Brain iron accumulation type 1 (NBIA1).
Image Unavailable-77436-900

Anti-phospho-MST3 (Thr178) Rabbit Polyclonal Antibody

Catalog Number: (77436-900)
Supplier: Bioss
Description: Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. Regulates cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.

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Product Image-89357-904

Anti-BIRC7 Rabbit Polyclonal Antibody

Catalog Number: (89357-904)
Supplier: Genetex
Description: The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq]
Image Unavailable-CAAAJ62917-MCR

Midostaurin

Supplier: Thermo Scientific Chemicals
Description: Inhibits a variety of serine/threonine and tyrosine kinases including PKC

Certificates

Image Unavailable-89158-212

Midostaurin ≥98% (by TLC)

Supplier: Enzo Life Sciences
Description: Inhibitor of a variety of serine/threonine and tyrosine kinases, like protein kinase C (PKC), cyclic AMP-dependent protein kinase (PKA), S6 kinase, Akt (protein kinase B; PKB), epidermal growth factor receptor (EGFR) tyrosine kinase activity and others including KDR, VEGFR, PDGFR, c-kit and other receptor tyrosine kinases. Potently inhibits FLT-3 kinase including mutant forms found in acute myeloid leukemia in vitro and in vivo. Apoptosis inducer. Showed broad antiproliferative activity against various tumor cell lines. Selectively inhibits T lymphocyte production of TNF-α. Upregulates endothelial nitric oxide synthase (eNOS; NOS III). Abrogates tumor angiogenesis in vivo.

Image Unavailable-IC0218379880

STAUROSPORINE PURE >98% C28H26N4O3 100UG

Catalog Number: (IC0218379880)
Supplier: MP Biomedicals
Description: STAUROSPORINE PURE >98% C28H26N4O3 100UG
Image Unavailable-IC0218379891

STAUROSPORINE >98% 62996-74-1 466.5 1MG

Catalog Number: (IC0218379891)
Supplier: MP Biomedicals
Description: STAUROSPORINE >98% 62996-74-1 466.5 1MG
Image Unavailable-IC0218379894

STAUROSPORINE >98% 62996-74-1 466.5 5MG

Catalog Number: (IC0218379894)
Supplier: MP Biomedicals
Description: STAUROSPORINE >98% 62996-74-1 466.5 5MG
Image Unavailable-IC0218379890

STAUROSPORINE PURE >98% C28H26N4O3 500UG

Catalog Number: (IC0218379890)
Supplier: MP Biomedicals
Description: STAUROSPORINE PURE >98% C28H26N4O3 500UG
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