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Product Image-MFLX01379-07

Masterflex® Plastic Ball Valves, Three-way, PVC, Avantor®

Supplier: SPECIALTY MFG CO
Description: Nonmetallic wetted parts ideal for water and mild aqueous solutions.

Product Image-89022-944

ESD Conveyor/Assembly Tray, MFG Tray

Supplier: Molded Fiber Glass Tray
Description: Used in the assembly of circuit boards, computers, medical device, and other types of electronic or static sensitive assembly

Image Unavailable-95032-350

Calcium sulfate dihydrate ≥98% NF

Supplier: Spectrum Chemicals
Description: Calcium Sulfate, Dihydrate, NF is used as an excipient for its filler and diluent properties. 

Certificates Small Business Enterprise

Image Unavailable-CAAAJ62834-03

Gentamicin sulfate 600 IU/mg

Supplier: Thermo Scientific Chemicals
Description: Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Reported to have low toxicity to mammalian cells and viruses at certain concentrations, useful for long-term tissue culture studies with viruses.

Certificates

Image Unavailable-56610-212

Accessories for Spill Containment Pallet/Platforms with Grating, Eagle Mfg

Catalog Number: (56610-212)
Supplier: Eagle Manufacturing
Description: For spill containment platforms (56610-161, 56610-163, 56610-202, 56618-544, 56618-546) 100% high-density polyethylene. Nonslip grid pattern. Low slope angle for ease of loading/unloading. 115.5Lx81.2Wx20.3Hcm. 680kg load capacity.
Product Image-MFLX01377-56

Masterflex® Plastic Ball Valves, Two-way Straight, Polypropylene, Avantor®

Supplier: SPECIALTY MFG CO
Description: Nonmetallic wetted parts ideal for water and mild aqueous solutions.

Product Image-470302-412

Soap Solution, APHA

Catalog Number: (470302-412)
Supplier: Ward's Science
Description: Shelf Life (months): 36<BR>Storage: Red<BR><BR>Please Note: This product is designed for educational and teaching laboratories and no certificate of analysis is available.

SDS


Image Unavailable-75812-298

Disodium hydrogen phosphate heptahydrate, granulated, BiotechGrade

Supplier: Spectrum Chemicals
Description: Sodium Phosphate Dibasic, Heptahydrate, Granular, BiotechGrade is used along with disodium hydrogen phosphate in food treatment to adjust pH. Spectrum offers highly pure reagents suitable for biochemical research and analysis. The critical parameters involved are absence of inhibitors such as traces of heavy metals as well as biochemical function tests for enzymes, coenzymes and enzyme substrates.

Certificates

Product Image-470164-864

Jr. Engineering Box: Pulleys and Gears

Catalog Number: (470164-864)
Supplier: KIDDER MFG. CO. LTD
Description: Add some student imagination and easily gathered items and students can start investigating pulleys and gears.
Image Unavailable-700013-134

Dextran, M.W. ~ 250,000, powder

Catalog Number: (700013-134)
Supplier: Spectrum Chemicals
Description: Dextran, 250,000, Powder is a complex branched glucan that is synthesized by certain lactic acid bacteria from sucrose. Commonly used in microsurgery to decrease the risk of vascular thrombosis, these agents are also used as effective osmotic agents and can treat hypovolemia. In the laboratory, Dextran is used to apply osmotic pressure to biological molecules and can, when applied with a fluorescent molecule, be used to create concentration gradients of diffusible molecules.

Certificates Small Business Enterprise


Product Image-470355-230

Rope, Twine, String and Yarn

Catalog Number: (470355-230)
Supplier: ROCKFORD MFG. CO.
Description: Educational Materials, Mechanics, Cotton, break strength 20 lbs., 420 ft.
Image Unavailable-76100-036

Anti-hHR23b Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (76100-036)
Supplier: Bioss
Description: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Image Unavailable-75811-800

Poloxamer 407 (Pluronic® F-127) NF

Supplier: Spectrum Chemicals
Description: Poloxamer 407, NF is a national formulary approved surfactant that finds utility because of its amphiphilic structure.

Certificates

Product Image-CA470354-412

Owl Pellets

Catalog Number: (CA470354-412)
Supplier: KIDDER MFG. CO. LTD
Description: Dehydrated, preserved owl pellets.
Product Image-75845-054

Open-Head UN Rated Poly Drum, With Metal Lever-Lock Ring, Eagle Mfg

Catalog Number: (75845-054)
Supplier: Eagle Manufacturing
Description: Drum is constructed of blue blow-molded high-density polyethylene (HDPE) with UV inhibitors and has a white lid with a metal lever-lock band closure.
Image Unavailable-76100-034

Anti-hHR23b Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Catalog Number: (76100-034)
Supplier: Bioss
Description: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilize XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is currently unavailable but limited stock may be available in our extended warehouse network. Please call 1-800-932-5000 and a VWR Customer Service Representative will help you.
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