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Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: AR—The standard Macron Fine Chemicals™ grade of analytical reagents; suitable for laboratory and general use. If the reagent also meets the requirements of the American Chemical Society Committee on Analytical Reagents, it will be denoted as an AR (ACS) reagent. 
Catalog Number: (10070-936)
Supplier: Prosci
Description: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it./Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity


Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Optimize biopharmaceutical fermentation and cell culture productivity and improve the efficiency of your pharmaceutical production and biopharmaceutical processes with our proven-effective vitamins and pharmaceutical process minerals.
Supplier: VWR International
Description: Used for measuring sodium chloride saturation of salt brines in various industries including food, fishing, and transportation.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Disodium hydrogen phosphate heptahydrate 98.0-100.5% (dried basis) USP, J.T.Baker®
Catalog Number: (CAJT3826-7)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Anhydrous. Suitable for buffer solutions. GMP manufactured.

Catalog Number: (CAJT5666-2)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: J.T.Baker® volumetric and analytical solutions. These solutions are suitable for use in ACS, USP and NF compendial methods and general laboratory applications.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Crystals. For biotechnology. GMP manufactured.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Disodium hydrogenphosphate 12-water. CAS RN 10039-32-4. Formula Weight: 358.14. Crystals, 'BAKER ANALYZED'* Reagent. Lot analysis on label. Packaged in a plastic container. Subject to postal/shipping restrictions. 12kg.
Supplier: Enzo Life Sciences
Description: Fodrin, also referred to as non-erythroid (αII-; brain) spectrin, is a tetrameric (αγ)2 actin-binding, fibrous protein, widely distributed in vertebrates, which forms part of the sub-membranous cytoskeleton within many cell types including neurons, and is particularly abundant with axons. The α-subunits of fodrins and spectrin are highly conserved phylogenetically, with the exception of human α-fodrin, which shares only 55-59% homology with erythroid-specific α-spectrins. The β-subunits of spectrin (and γ-subunits of fodrins) are species specific. The interleukin-1 converting enzyme (ICE) family of proteases has been implicated as important effectors of the apoptotic pathway, perhaps acting hierarchically in a protease cascade. Neuronal fodrin is known to be cleaved by calpain following ischaemic insult and it has been proposed that calpain and an unidentified protease play a role in the onset of neuronal death following transient forebrain ischaemia. Recently, an ICE-like protease has been implicated in the early cleavage of fodrin, producing a 150kDa fragment, proximal to CPP32 in Fas-induced and C2-ceramide mediated apoptosis. A cleavage product of α-fodrin has been proposed as a candidate autoantigen in primary Sjögren’s syndrome and α-fodrin has been shown to be the source of a so-called ‘inhibitory protein factor’ family, members of which have been shown to inhibit both GABA and ATP-dependent glutamate uptake into purified synaptic vesicles.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: GMP manufactured. Suitable for buffer solutions.
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Avantor excipients are used during the formulation process in a wide range of applications. Avantor provides high-purity and performance excipients that serve as fillers, binders, disintegrants, lubicants, flavors, emulsifiers and preservatives. All the products are cGMP produced and meet USP grade standards.
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Achieve control over laboratory variables -- minimizing variability and maximizing consistency of results -- by relying on salts in a variety of grades - ACS, BAKER, etc.
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Avantor excipients are used during the formulation process in a wide range of applications. Avantor provides high-purity and performance excipients that serve as fillers, binders, disintegrants, lubicants, flavors, emulsifiers and preservatives. All the products are cGMP produced and meet USP grade standards.
Supplier: VWR
Description: Suitable for bioprocessing. BSE/TSE free. Endotoxin tested. Custom packaging and testing available. Change management and notification available. Samples available.
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Granular. GMP manufactured.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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