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Supplier: Biotium
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Catalog Number: (76083-124)
Supplier: Bioss
Description: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.


Catalog Number: (10434-224)
Supplier: Bioss
Description: Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.


Catalog Number: (89416-716)
Supplier: Prosci
Description: Aldh3A2 Antibody: Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.


Catalog Number: (10086-156)
Supplier: Proteintech
Description: Deltex homolog 1 (E3 ubiquitin-protein ligase DTX1) is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.DTX1 is conserved from Drosophila, and is expressed in a wide array of tissues, particularly in the central nervous system, testes, and endothelial cells, mainly colocalized with Notch1.It contains a RING-type zinc finger and 2 WWE domains. This antibody recognizes DTX1 protein (72kd) and it's isoforms (about 60kd).


Supplier: Brady Worldwide
Description: GlobalMark tapes are easy to install and very durable

Catalog Number: (10111-338)
Supplier: Prosci
Description: TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.


Catalog Number: (75811-702)
Supplier: Spectrum Chemicals
Description: Magnesium Stearate, NF, BP, JP is used as an anti-adherent in the manufacture of of medical capsules, tablets, and powders.


Supplier: Bachem Americas
Description: BNP, originally isolated from porcine brain, belongs to the class of natriuretic peptides, having an amino acid sequence and a pharmacological activity spectrum (including diuretic-natriuretic, hypotensive, and vasorelaxant actions) remarkably similar to that of atrial natriuretic peptide (ANP). Meanwhile, BNP precursor molecules have also been shown to exist in human and rat cardiac tissue. Comparison of the precursor sequences demonstrates structural species differences between the mammalian BNPs, a finding which contrasts with the highly conserved ANP sequences.

Catalog Number: (75812-266)
Supplier: Spectrum Chemicals
Description: Silicon Dioxide, 325 Mesh, FCC.

Supplier: Spectrum Chemicals
Description: Isopropyl Alcohol, 99 Percent, USP, JP has many uses, including as a pharmaceutical raw material for preparing USP Rubbing Alcohol for relief of muscle stiffness and an infection preventative for minor scrapes and burns.
Supplier: MilliporeSigma
Description: Potassium bromide is transparent from the near UV to long wave IR wavelengths. In IR-spectroscopy, solid samples which are difficult to melt or dissolve in any suitable IR-transmitting solvent, are analyzed by grinding with Potassium bromide powder, and pressing into a disc. This procedure has a high quality demand of the used potassium bromide. Potassium bromide Uvasol® is adjusted to a mean particle size of 150 μm. This is sufficient for the preparation of perfectly good pellets without the need for further pre-treatment and the associated risk of contamination. It also retains its powdery form over a period of years if stored in an air-tight condition. Its physical suitability for pelletising is checked by a special application test and its chemical purity established by full spectrum FT-IR analysis.
Supplier: Spectrum Chemicals
Description: Potassium Sorbate, Powder, FCC is used as an antimicrobial preservative. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage, nutritional supplement and personal care applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities

Supplier: Thermo Scientific Chemicals
Description: Neodymium(III) chloride hydrate is used for production of neodymium metal. It also finds application in lasers and fiber amplifiers. It serves as dopants for silica based as well as plastic fibers. It plays an important role of additives in organic light emitting diodes resulting in improved LED emission spectrum. In addition, it is used in catalysis of polymerization of various dienes. It is used to modify titanium dioxide for use as a photocatalyst. Its coating on aluminum and its alloy protect them from corrosion. It is also extensively used as fluorescent labels for organic molecules.
Catalog Number: (CA10852-398)
Supplier: Spectrum Chemicals
Description: SESAME OIL, NF also known as til oil, is an oil derived from the sesame seed. As an edible vegetable oil, it is widely used in most Eastern and some Middle Eastern cuisine's as a flavor eNHancer. It is also used in the personal care industry in soap production, as cosmetic oil carrier and as the base for massage oils. Medicinally, its major use is as a solvent in the preparation of sustained-release intramuscular / subcutaneous injections of oil soluble actives such as steroids and avermectins. It is also used as an excipient in suspensions and emulsions, ointments, liniments, ophthalmic preparations, oral capsules and suppositories. Spectrum Chemical NF SESAME OIL products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities. Storage temperature - LIGHT SENSITIVE: Keep tightly closed in light-resistant containers. Prevent exposure to excessive heat.

Catalog Number: (CA95036-208)
Supplier: Spectrum Chemicals
Description: Tartaric Acid, Granular, NF is used as an antioxidant, acidifier, flavor enhancer, stabilizer and sequestering agent. All Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities

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