VWR, Part of Avantor - Chemicals and laboratory scientific supplies

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Ferrocene 99%

Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00001427

Certificates

2,2'-Bipyridyl ACS, GR for analysis, reagent for iron(II) and molybdenum, Supelco®

Supplier: MilliporeSigma

Description: Reagent for iron(II) and molybdenum

SDS Certificates

Anti-Hephaestin Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (76099-944)

Supplier: Bioss

Description: Hephaestin is a single-pass type I membrane protein that belongs to the multicopper oxidase family of proteins. Hephaestin, a copper-dependant ferroxidase protein, is crucial for iron exiting intestinal enterocytes into the circulation. It mediates the movement of iron across the basolateral membrane in conjunction with ferroportin 1. This is an important link between iron and copper metabolism in mammalian systems, as copper deficiency leads to reduced hephaestin and reduced iron absorption resulting in anemia. Hephaestin can bind six copper ions per monomer and is regulated by the homeobox transcription factor CDX2. Increased levels of iron leads to an increase in CDX2 expression and thus Hephaestin. Hephaestin is primarily detected in the intestine, but is also expressed in colon, breast, bone trabecural cells and fibroblasts.

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Iron and Manganese Color Disc Test Kit, Model IR-20, Hach

Catalog Number: (CA1463-00)

Supplier: Hach

Description: When customers complain of stained and dingy laundry, this kit lets you do quick, on-the-spot tests for iron and manganese to see where the problem lies.

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Pipe Stem Triangles

Supplier: United Scientific Supplies

Description: Triangles made from galvanized iron wire, with porcelain pipe stemming to reduce wire sagging and oxidation.

Anti-ISCU Rabbit Polyclonal Antibody

Catalog Number: (10088-986)

Supplier: Proteintech

Description: Iron-sulfur (Fe-S) clusters are required for the functions of mitochondrial aconitase, mammalian iron regulatory protein 1, and many other proteins in multiple subcellular compartments. Mitochondrial and cytosolic isoforms of the human Fe-S cluster scaffold protein, iron-sulfur cluster assembly enzyme (ISCU), is involved in activation of iron uptake, redistribution of intracellular iron, and decreased utilization of iron in Fe-S proteins.
Defects in ISCU gene are the cause of myopathy with exercise intolerance Swedish type (MEIS), which is characterized by lifelong severe exercise intolerance . Two ISCU isoforms ISCU1 (cytosolic, 15 kDa) and ISCU2 (mitochondrial, 18 kDa), were produced by alternative splicing, and ISCU2 is considered the canonical isoform1. ISCU2 protein is rapidly processed upon maturation . Proteintech’s ISCU antibody 14812-1-AP is raised against the full-length ISCU2 and is expected to detect 14 kDa,15 kDa and 18-19 kDa bands which has been reported in the previous observation .

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HEMATOGNOST Fe® stain for histology, Sigma-Aldrich®

Catalog Number: (CA1.12084.0001)

Supplier: MilliporeSigma

Description: Used to detect free ionic iron using the Prussian blue method in cells and tissues

Certificates

Anti-MMS19 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10664-316)

Supplier: Bioss

Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.

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Anti-MMS19 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10664-310)

Supplier: Bioss

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Iron Color Disc Test Kit, Model IR-18, Hach

Catalog Number: (CA97026-882)

Supplier: Hach

Description: Using the simple color disc method, this kit measures Iron (medium range - 0.1-5 mg/L) and contains 100 tests.

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Cast Iron Support Stands with Rods, United Scientific Supplies

Supplier: United Scientific Supplies

Description: Tip-free stability for experiments.

Lab Stand, Glas-Col

Catalog Number: (58954-025)

Supplier: Glas-Col

Description: Heavy duty lab stand made to last with stainless steel mast and cast iron base.

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A-Frame Base

Supplier: Wards

Description: This cast iron base features threads for rods sized 1/2 - 13.

Anti-HAMP Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10665-002)

Supplier: Bioss

Description: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].