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Image Unavailable-10456-276

Anti-GNL3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10456-276)
Supplier: Bioss
Description: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells.
Image Unavailable-10456-272

Anti-GNL3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10456-272)
Supplier: Bioss
Description: Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell cycle progression in stem cells and cancer cells.
Product Image-470351-994

miniPCR® Viral Diagnostics Lab: Beating the Next Pandemic

Catalog Number: (470351-994)
Supplier: AMPLYUS LLC
Description: A new virus is spreading across the globe!
Product Image-CA89013-352

Hemoccult® ICT Immunochemical Fecal Occult Blood Test, Beckman Coulter®

Supplier: Beckman Coulter
Description: This immunochemical fecal occult blood test features high specificity and sensitivity, and is clinically proven to detect bleeding associated with more cancers and polyps than traditional guaiac-based tests.

Product Image-10784-692

PrimaCell™, Human Cervical Tumor Cell Culture Kit, CHI Scientific

Catalog Number: (10784-692)
Supplier: CHI Scientific
Description: The PrimaCell™ system has been developed for the acquisition and growth of primary cells from a variety of different tissue types. Each PrimaCell™ kit has been optimized for each cell type to produce 4-7 times the number of primary cells obtained from published literature protocols. Each kit comes with 100 ml of tissue washing medium, our optimized tissue dissociation system OptiTDS™, 500 ml of growth medium, and enough growth supplements and serum to add to the supplied medium. Kits that require a Fibroblast control system also come with our FibrOut™ kit (added to the growth medium) which reduces or eliminates Fibroblast growth after 2-3 cell growth cycles.
Image Unavailable-10454-024

Anti-ZNF146 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10454-024)
Supplier: Bioss
Description: Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
Product Image-CA10001-444

SpeedStreaks™ Disposable Loop

Supplier: Hardy Diagnostics
Description: Hardy Diagnostic Loops are sterile and free of lubricants, oils, and electrostatic charges.

Product available on GSA Advantage®

Product Image-10748-774

Anti-DACT3 Rabbit Polyclonal Antibody

Catalog Number: (10748-774)
Supplier: Prosci
Description: Dact3 Antibody: The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact3, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact3 is expressed in the ventral region of maturing somites, limb bud and branchial arch mesenchyme, embryonic CNS, and the adult brain. Recent evidence shows that Dact3 acts as a negative regulator Wnt/beta-catenin signaling that is repressed at the transcriptional level in colorectal cancer and this repression is associated with bivalent histone modifications. This repression can be reversed by pharmacological agents that targets both histone methylation and deacetylation, suggesting that Dact3 may be a potential target for therapeutic treatment of this cancer. At least three isoforms of Dact3 are known to exist.
Product Image-10749-096

Anti-DIRAS3 Rabbit Polyclonal Antibody

Catalog Number: (10749-096)
Supplier: Prosci
Description: DIRAS3 is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with mono-allelic expression of the paternal allele, which is associated with growth suppression and down-regulation of cyclin D1 promoter activity and induction of p21 (WAF/CIP1). Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. DIRAS3 has been shown to induce autophagy in human ovarian cancer cells by blocking PI3K signaling, inhibiting the mammalian target of rapamycin (TOR), upregulating ATG4, and colocalizing with LC3 in autophagosomes. DIRAS also interacts with C-RAF and downregulates mitogen-activated protein kinase kinases (MEK) to restrict cell migration.
Image Unavailable-CAAA12151-30

Chromium disilicide 99+% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: 99+% (metals basis).Powder,WARNING: Inhalation of fumes or dust may be a cancer hazard,50g,250g.

Certificates

Image Unavailable-75791-872

Human Recombinant Spondin 2 (from Cells)

Catalog Number: (75791-872)
Supplier: Prosci
Description: Spondin-2, also referred to as mindin, belongs to the F-spondin family of secreted extracellular matrix proteins. Spondins are characterised by the presence of F-spondin domains 1 and 2 (FS1 and FS2) at the N-terminus and a thrombospondin-type 1 repeat (TSR1) domain at the C-terminus. Spondin-2 functions as a pattern-recognition molecule for bacterial and viral pathogens and as an integrin ligand for inflammatory cell recruitment and T cell priming. In addition to its roles in promoting neuron outgrowth and inhibiting both cancer and angiogenesis, Spondin-2 plays an important role in the initiation of the immune response and is involved in inflammatory processes.
Image Unavailable-10427-670

Anti-SSX8 Rabbit Polyclonal Antibody

Catalog Number: (10427-670)
Supplier: Bioss
Description: SSX8 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas.
Product Image-CA89492-730

CTA (Cystine Tryptic Agar), Hardy Diagnostics

Supplier: HARDY DIAGNOSTICS CA
Description: CTA (Cystine Tryptic Agar), 3mL Deep, 13x100mm tube, optically clear, shatter resistant, polycarbonate tube, order by the package of 20, by Hardy Diagnostics.

Certificates

Product Image-89417-652

Anti-PIWIL2 Rabbit Polyclonal Antibody

Catalog Number: (89417-652)
Supplier: Prosci
Description: PIWI-L2 Antibody: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers.
Image Unavailable-10471-722

Anti-SART1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10471-722)
Supplier: Bioss
Description: SART1 encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri snRNP to the pre spliceosome in the spliceosome assembly pathway.
Product Image-10752-086

Anti-LRRC26 Rabbit Polyclonal Antibody

Catalog Number: (10752-086)
Supplier: Prosci
Description: The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues. LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis. LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels.
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