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Image Unavailable-10454-008

Anti-ZNF146 Rabbit Polyclonal Antibody

Catalog Number: (10454-008)
Supplier: Bioss
Description: Tissue specificity: Liver, skeletal and heart muscle, mammary cells. Very low levels in brain, lung, placenta and kidney. Strongly overexpressed in many pancreas and colorectal cancers. Increased gene copy numbers are detected in 3 of 12 tumor cell lines and 2 of 12 primary pancreatic carcinomas. Overexpresseed in 80% of colorectal cancers.
Image Unavailable-15156-150

Accessories for Safetex NO-TOUCH® Pap Smear Kits and Accessories, Andwin Scientific

Catalog Number: (15156-150)
Supplier: Andwin
Description: Accessories for Safetex NO-TOUCH® Pap Smear Kits and Accessories, Andwin Scientific

SDS Small Business Enterprise Minority or Woman-Owned Business Enterprise


Image Unavailable-76119-986

Anti-DUSP26 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76119-986)
Supplier: Bioss
Description: Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).Tissue specificity:Brain. In the brain it is expressed ubiquitously except in the hippocampus. Expressed in embryonal cancers (retinoblastoma, neuroepithilioma and neuroblastoma) and in anaplatic thyroid cancer.
Product Image-470126-644

Cholesterol Diagnostic Lab Activity

Catalog Number: (470126-644)
Supplier: Edvotek
Description: Simulate Testing for the FH Gene
Image Unavailable-10086-386

Anti-EIF3M Mouse Monoclonal Antibody [clone: 2A12B2]

Catalog Number: (10086-386)
Supplier: Proteintech
Description: EIF3M gene encodes eukaryotic translation initiation factor (eIF) subunit M, also called GA17 or PCID1. eIF-3 complex is required for several steps in the initiation of protein synthesis, and recent studies indicate that regulation of oncogene expression and neoplastic transformation are controlled by eIF subunits. The most uncharacterized non-core subunit EIF3M was confirmed to be highly expressed in human cancer cell lines and colon cancer patient tissues and mediate regulation of tumorigenesis-related genes in human colon cancer.
Product Image-76334-640

Viral Transport Medium (VTM), Hardy Diagnostics

Catalog Number: (76334-640)
Supplier: Hardy Diagnostics
Description: Hardy Diagnostics Viral Transport Medium is recommended for the collection and transport of clinical specimens for the recovery of viral agents.

Certificates


Product Image-10750-542

Anti-MACC1 Rabbit Polyclonal Antibody

Catalog Number: (10750-542)
Supplier: Prosci
Description: MACC1 Antibody: Metastasis associated in colon cancer 1 (MACC1) is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (MET) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. MACC1 protein consists of four domains: ZU5, SH3, and two C-terminal death domains (DD). Expression of MACC1 was found significantly upregulated in malignant tissues (colon cancer of all stages as well as liver and lung metastases) compared to normal tissues or adenomas. MACC1 represents an early and crucial prognostic indicator for colon cancer metastasis that is independent of age, sex, tumor infiltration, nodal status, and lymph vessel invasion. Besides its involvement in signal transduction with the MET receptor, MACC1 also links MET signaling and apoptosis. MACC1 may also be an important therapeutic target for colorectal cancer treatment.
Image Unavailable-CA90003-748

Diagnostic Tests—Adjuvant Complete to Neisseria meningitidis Antiserum, BD Diagnostics

Supplier: BD
Description: Antigens and antisera used for slide agglutination tests and immunofluorescence. BD Difco Listeria O Antigens Types 1 and 4 (Slide) are suspensions of appropriate<i> </i>serotypes containing 0.3% formaldehyde as a preservative

SDS Certificates

Image Unavailable-CAPIPA5-12942

Anti-BRAF Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-12942)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with mouse based on sequence homology. BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Product Image-89234-238

Laboratory Animal Cancer Implant Needles, Cadence Science®

Supplier: Cadence Science
Description: Two piece needle set consists of a sharp pointed stainless steel outer cannula and a stainless steel blunt obturator which protrudes 3.2mm (1/8") beyond the needle point

Product Image-470315-658

ADC® Diagnostix 5110N Pocket Diagnostic Sets

Supplier: AMERICAN DIAGNOSTIC CORP CP
Description: A pocket sized set with a protective hard case.

Product Image-10751-250

Anti-BCL9L Rabbit Polyclonal Antibody

Catalog Number: (10751-250)
Supplier: Prosci
Description: Bcl9L Antibody: Bcl9L, a homolog of Bcl9, was initially identified through a bioinformatics screening. It is expressed in fetal brain, adult lung, eye and prostate, in addition to several types of tumors including pancreatic and prostate cancers. Bcl9L has been shown to interact with beta-catenin, a target of the Wnt signaling pathway, and is required for enhanced beta-catenin-T-cell factor (TCF)-mediated transcription in colorectal tumor cells, possibly by translocating beta-catenin to the nucleus. Other studies have indicated that Bcl9L expression correlates with high nuclear grade cancer phenotype and the expression of ErbB2/HER-2 in breast cancers, suggesting that activity may occur in other types of cancer. Bcl9L has also been shown to be critical for Wnt-mediate regulation of stem cell traits in colon epithelium and adenocarcinomas which are associated with tumor invasion, metastasis, and resistance to therapy.
Product Image-77590-058

Crystal Digital PCR® Assay for KRAS (G12, G12C)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (G12, G12C) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify one mutation in the KRAS gene using the ruby chip. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

New Product

Product Image-10086-460

Anti-ELAC2 Rabbit Polyclonal Antibody

Catalog Number: (10086-460)
Supplier: Proteintech
Description: Putative prostate cancer susceptibility protein (ELAC2) is encoded by HPC2/ELAC2 gene. HPC2 is a potential prostate cancer predisposition gene playing a role in genetic susceptibility to prostate cancer.It is a zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity and probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.Defects in ELAC2 may be a cause of susceptibility to prostate cancer (PC).
Image Unavailable-CAPIPA5-12836

Anti-BRAF Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-12836)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, chicken, mouse and rat based on sequence homology. BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.
Product Image-470315-666

ADC® Proscope 5215 Diagnostic Set

Catalog Number: (470315-666)
Supplier: AMERICAN DIAGNOSTIC CORP CP
Description: Five instruments in a fitted case.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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