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Anti-Mammaglobin A Rabbit Monoclonal Antibody [clone: EPR 9092]

Catalog Number: (CA76634-866)
Supplier: Diagnostic Biosystems
Description: The mammaglobin gene was first identified using a differential screening approach directed at the isolation of novel, human breast cancer-associated genes. Mammaglobin-A is highly overexpressed in breast cancer cell lines and primary breast tumors. This pattern of expression is restricted to mammary epithelium and metastatic breast tumors. Thus, mammaglobin-A-specific T cell immune responses may provide an important approach for the design of breast cancer-specific immunotherapy.
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Anti-CA 125 Mouse Monoclonal Antibody [clone: OV185:1]

Catalog Number: (CA76634-504)
Supplier: Diagnostic Biosystems
Description: This antibody reacts specifically with CA 125 ovarian cancer antigen. Several studies have shown that CA 125 is a useful tumor marker for ovarian epithelial malignancies. However, CA 125 has been described in other neoplasms such as seminal vesicle and anaplastic lymphomas.
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Anti-Cyclin D1 Rabbit Monoclonal Antibody [clone: EP12]

Catalog Number: (CA76634-882)
Supplier: Diagnostic Biosystems
Description: Cyclin D1 belongs to the Cyclin D family. Cyclin D1 is required for the cell cycle G1/S transition. Amplification or overexpression of Cyclin D1 plays a pivotal role in the development of various human cancers including breast cancer, colon cancer, melanoma, prostate cancer and lymphoma. It is useful to differentiate mantle cell lymphoma from small cleaved cell lymphoma. Rabbit monoclonal antibodies to Cyclin D1 showed the highest sensitivity to detect this antigen in formalin fixed paraffin embedded tissue as compared to several other clones.
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Anti-PD-1 Mouse Monoclonal Antibody [clone: EH33]

Supplier: Diagnostic Biosystems
Description: The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies targeting the PD-1/PD-L1 pathway have the potential to improve response and thereby offer a novel treatment avenue to some patients with cancer.

Image Unavailable-CA76634-864

Anti-ERG Rabbit Monoclonal Antibody [clone: EP111]

Catalog Number: (CA76634-864)
Supplier: Diagnostic Biosystems
Description: ERG, the ETS related gene, belongs to the ETS family that plays important roles in cell development, differentiation, proliferation, apoptosis and tissue remodeling. The ERG antibody identifies endothelial cells, lymphocytes and prostate cancer cells.
Image Unavailable-CA76633-246

Anti-P53 Protein Mouse Monoclonal Antibody [clone: DO7]

Supplier: Diagnostic Biosystems
Description: This antibody reacts with wild as well as mutant types of P53 protein. It recognizes an epitope in the N-terminus of P53 protein, known to reside between amino acids 35 to 45. This antibody can be demonstrated in 22 to 76% of the colon, stomach, bladder, breast, lung and testes cancers.

Image Unavailable-CA76634-602

Anti-HER2/neu (c-erbB-2) Rabbit Polyclonal Antibody

Catalog Number: (CA76634-602)
Supplier: Diagnostic Biosystems
Description: This antibody recognizes a c-erbB-2 protein, which is a receptor tyrosine kinase of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. c-erbB-2 oncoprotein is detectable in a subset of breast and other adenocarcinomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
Product Image-10810-020

Paraffin wax blended with synthetic polymers, Solidification point: 56-58°C, PureAffin® R56™ for infiltration and embedding

Catalog Number: (10810-020)
Supplier: CANCER DIAGNOSTICS, INC.
Description: Infiltration and Embedding Paraffin. A blend of fully refined paraffin wax and select additives. A minimal compression histology wax (56-58°C)

SDS


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Anti-GCDFP-15 Mouse Monoclonal Antibody [clone: DBM15.52]

Supplier: Diagnostic Biosystems
Description: It recognizes a protein of 15 kDa, identified as Gross cystic disease fluid protein 15 (GCDFP-15). It is a major protein component of benign breast gross cysts. It is a known marker of breast cancer, as it is found in approximately 50% of all breast cancer specimens. GCDFP-15, also known as PIP, for prolactin inducible protein, is a prolactin and androgen controlled protein. This antibody is useful in the identification of metastatic breast carcinoma, or fluid analysis.

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Anti-CDX2 Rabbit Monoclonal Antibody [clone: EP25]

Supplier: Diagnostic Biosystems
Description: The caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferation and differentiation of intestinal epithelial cells. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX2 and carbonic anhydrase 1, a gene regulated by CDX2, is reduced or absent. CDX-2 is one of the important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract.

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Anti-PD-L1 Mouse Monoclonal Antibody [clone: 405-9A11]

Supplier: Diagnostic Biosystems
Description: The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies targeting the PD-1/PD-L1 pathway have the potential to improve response and thereby offer a novel treatment avenue to some patients with cancer.

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Anti-PD-L1 Mouse Monoclonal Antibody [clone: 405-9A11]

Catalog Number: (CA76634-554)
Supplier: Diagnostic Biosystems
Description: The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies targeting the PD-1/PD-L1 pathway have the potential to improve response and thereby offer a novel treatment avenue to some patients with cancer.
Image Unavailable-CA76634-556

Anti-PD-1 Mouse Monoclonal Antibody [clone: EH33]

Catalog Number: (CA76634-556)
Supplier: Diagnostic Biosystems
Description: The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 interaction. Precision therapies targeting the PD-1/PD-L1 pathway have the potential to improve response and thereby offer a novel treatment avenue to some patients with cancer.
Image Unavailable-CA76633-614

Anti-Thymidine Phosphorylase Mouse Monoclonal Antibody [clone: P-GF.44C]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to a 55 kDa protein known as platelet-derived endothelial growth factor (PD-ECGF), or thymidine phosphorylase (TP). High levels of TP/PD-ECGF are observed in cancer patients. High intracellular levels of TP/PD-ECGF are associated with increased sensitivity to fluoropyrimidine chemotherapeutic agents.

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Anti-Tag-72 Mouse Monoclonal Antibody [clone: B72.3]

Supplier: Diagnostic Biosystems
Description: This antibody is specific to an oncofetal antigen of >1,000 kDa known as tumor associated glycoprotein (TAG-72) or CA 72-4. This antibody defines the mucin carried sialylated-Tn antigen. This antibody stains the majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary and non-small cell lung cancer.

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Anti-P53 Mouse Monoclonal Antibody [clone: DO7]

Catalog Number: (CA76634-274)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with wild as well as mutant types of P53 protein. It recognizes an epitope in the N-terminus of p53 protein, known to reside between amino acids 35 to 45. This antibody can be demonstrated in 22 to 76% of the colon, stomach, bladder, breast, lung and testes cancers.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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