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Image Unavailable-10415-288

Anti-MAPT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10415-288)
Supplier: Bioss
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Product Image-97051-416

Plastic Vials, Caps and Convenience Kits for LCMS and HPLC

Supplier: MicroSolv Technology Corp
Description: Sample safe clear or amber plastic vials for biological, ionic and sensitive analytes.

Product Image-10068-996

Anti-MAPT Rabbit Polyclonal Antibody

Catalog Number: (10068-996)
Supplier: Prosci
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Product Image-10069-012

Anti-MAPT Rabbit Polyclonal Antibody

Catalog Number: (10069-012)
Supplier: Prosci
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Product Image-10070-232

Anti-MAPT Rabbit Polyclonal Antibody

Catalog Number: (10070-232)
Supplier: Prosci
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Image Unavailable-76078-080

Anti-Tau protein Ser214 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76078-080)
Supplier: Bioss
Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Product Image-CA100-401-395

Anti-CTSA Rabbit Polyclonal Antibody

Catalog Number: (CA100-401-395)
Supplier: Rockland Immunochemical
Description: This antibody is suitable for the detection of human PPCA (54-, 32-, and 20-kDa) on Western blot, by immunoprecipitation, immunochemistry, and ELISA of either transfected cells (e.g. COS-1 cells) or primary cells (e.g. fibroblasts).
Product Image-CA613-4228

Anti-IgG Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (CA613-4228)
Supplier: Rockland Immunochemical
Description: Anti-Sheep Secondary Antibody is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting. This product is also suitable for multiplex analysis, including multicolor imaging, utilizing various co

SDS


Image Unavailable-10058-832

Zero Dilution Inner Liner for PerkinElmer Auto SYS™ and Clarus GCs Equipped with Split/Splitless Inlets, Restek

Catalog Number: (10058-832)
Supplier: Restek
Description: Use of these liners helps ensure an inert GC flow path for higher sensitivity, accuracy, and reproducibility.
Image Unavailable-77561-416

Human Recombinant PI3K (p110 alpha (E542K, His tag)/p85 alpha, His tag), Active (from Baculovirus-Insect Cells)

Supplier: Sino Biological
Description: Recombinant full length human p110 alpha (E542K) mutant subunit and human p85 alpha wild-type subunit were co-expressed by baculovirus in Sf9 insect cells using an N-terminal His tag on both proteins.

New Product

Image Unavailable-75969-166

Anti-TP53 Mouse Monoclonal Antibody (Biotin) [clone: TRP/816]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Image Unavailable-75967-688

Anti-TP53 Mouse Monoclonal Antibody (Biotin) [clone: TRP/817]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Image Unavailable-CAAAAA17361-0B

Amberlyst® A-26 (OH), Amberlyst™ ion exchange resin

Supplier: Thermo Scientific Chemicals
Description: Macroreticular strongly basic anion exchange resin, hydroxide form, suitable for aqueous and non-aqueous applications. Useful for removal of anionic metal complexes and mercaptans from non-polar solvents, and of acidic impurities from organic solutions.

Certificates

Product Image-76262-738

Anti-TP53 Rabbit Polyclonal Antibody

Catalog Number: (76262-738)
Supplier: Rockland Immunochemical
Description: TP53 (tumor suppressor gene p53) is one of the most well-studied genes that suppresses tumor formation and renders protection against DNA damage by inducing cell cycle arrest, DNA repair, or apoptosis. TP53 signaling is triggered through numerous cellular events ranging from DNA damage to hypoxia, stress and a plethora of other causes. Upon activation, p53 acts as zinc-containing transcriptional regulator and initiates a cascade of events that determines the cellular outcome including cell cycle arrest, apoptosis, senescence, DNA repair, development, differentiation and tissue homeostasis. Cell cycle arrest is induced by p53 via trans-activating genes such as p21 (CDK-inhibitor 1, cyclin dependent kinase) and others. Interestingly, p53 itself is capable of triggering cellular responses (survival or induced cell death) as well. Mutations or deletions in the TP53 gene are present in nearly 50% of human cancers, and primarily results in impaired tumor suppressor function. Anti-p53 (ac Lys305) antibody is ideal for researchers interested in developmental biology, cell growth and cancer research.
Product Image-76262-722

Anti-TP53 Rabbit Polyclonal Antibody

Catalog Number: (76262-722)
Supplier: Rockland Immunochemical
Description: TP53 (tumor suppressor gene p53) is one of the most well-studied genes that suppresses tumor formation and renders protection against DNA damage by inducing cell cycle arrest, DNA repair, or apoptosis. TP53 signaling is triggered through numerous cellular events ranging from DNA damage to hypoxia, stress and a plethora of other causes. Upon activation, p53 acts as zinc-containing transcriptional regulator and initiates a cascade of events that determines the cellular outcome including cell cycle arrest, apoptosis, senescence, DNA repair, development, differentiation and tissue homeostasis. Cell cycle arrest is induced by p53 via trans-activating genes such as p21 (CDK-inhibitor 1, cyclin dependent kinase) and others. Interestingly, p53 itself is capable of triggering cellular responses (survival or induced cell death) as well. Mutations or deletions in the TP53 gene are present in nearly 50% of human cancers, and primarily results in impaired tumor suppressor function. Anti-p53 (ac Lys292) antibody is ideal for researchers interested in developmental biology, cell growth and cancer research.
Product Image-10852-012

Rtx®-5MS GC Columns, Restek

Supplier: Restek
Description: Low-bleed columns developed for mass spectrometers and the analysis of semi-volatile pollutants.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


VWR will not lift restrictions for residential shipping addresses.

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This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
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