You Searched For: Osmium+(IV)+oxide

Catalog Number: (10782-368)

Supplier: Biosensis

Description: FUNCTION: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. May be involved in copper homeostasis/oxidative stress through copper ion reduction. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. FUNCTION: Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. Rat and mouse beta-amyloid peptides bind only weakly transient metals and have little reducing activity due to substitutions of transient metal chelating residues. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation (By similarity). FUNCTION: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis. SUBUNIT: Binds, via its C-terminus, to the PID domain of several cytoplasmic proteins, including APBB family members, the APBA family, MAPK8IP1, SHC1, Numb and Dab1. Binding to Dab1 inhibits its serine phosphorylation. Also interacts with GPCR-like protein BPP, FPRL1, APPBP1, IB1, KNS2 (via its TPR domains), APPBP2 (via BaSS) and DDB1. In vitro, it binds MAPT via the MT-binding domains. Associates with microtubules in the presence of ATP and in a kinesin-dependent manner. Interacts, through a C-terminal domain, with GNAO1. Amyloid beta-42 binds CHRNA7 in hippocampal neurons. Beta-amyloid associates with HADH2. TISSUE SPECIFICITY: different isoforms in different tissues: kidney. brain. liver. hippocampus, substania nigra pars compacta and cerebellum. In the cerebellum, all the isoforms are abundantly expressed in Purkinje cells.

Supplier: Electron Microscopy Sciences

Description: Paraformaldehyde is the condensation product of methylene glycol, a substance not so far isolated in its pure form; it is a white solid with a formaldehyde content between 78 and 98% and is supplied either as a Prill or Granular.

Catalog Number: (100495-096)

Supplier: Electron Microscopy Sciences

Description: All MAC X-ray Microanalysis standards are suitable for electron-beam energy dispersive or wavelength dispersive X-ray microanalysis systems.

Catalog Number: (10782-366)

Supplier: Biosensis

Description: FUNCTION: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. May be involved in copper homeostasis/oxidative stress through copper ion reduction. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. FUNCTION: Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. Rat and mouse beta-amyloid peptides bind only weakly transient metals and have little reducing activity due to substitutions of transient metal chelating residues. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses. Promotes both tau aggregation and TPK II-mediated phosphorylation (By similarity). FUNCTION: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis. SUBUNIT: Binds, via its C-terminus, to the PID domain of several cytoplasmic proteins, including APBB family members, the APBA family, MAPK8IP1, SHC1, Numb and Dab1. Binding to Dab1 inhibits its serine phosphorylation. Also interacts with GPCR-like protein BPP, FPRL1, APPBP1, IB1, KNS2 (via its TPR domains), APPBP2 (via BaSS) and DDB1. In vitro, it binds MAPT via the MT-binding domains. Associates with microtubules in the presence of ATP and in a kinesin-dependent manner. Interacts, through a C-terminal domain, with GNAO1. Amyloid beta-42 binds CHRNA7 in hippocampal neurons. Beta-amyloid associates with HADH2. TISSUE SPECIFICITY: different isoforms in different tissues: kidney. brain. liver. hippocampus, substania nigra pars compacta and cerebellum. In the cerebellum, all the isoforms are abundantly expressed in Purkinje cells.

Supplier: Thermo Scientific Chemicals

Description: Molecular Formula: (NH4)2OsCl6 in 20% HCl
Physical Form: Liquid
UN No.: 1789
MDL No.: MFCD00011147

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Supplier: Thermo Scientific Chemicals

Description: Dodecacarbonyltriosmium 99%

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Catalog Number: (BDH7253-1)

Supplier: VWR International

Description: Made with purified water and dilute ACS grade sulfuric acid.

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Catalog Number: (CAJT2896-0)

Supplier: VWR International

Description: Lot analysis on label.

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Catalog Number: (80721-166)

Supplier: VWR

Description: 1 ml= 33.22 mg Ce(SO4)2

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Catalog Number: (JT2890-3)

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Crystals. Lot analysis on label.

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Supplier: VWR International

Description: Labels provide a cost-efficient means of security where tamper-evident seals are necessary.

Catalog Number: (CAJT5626-2)

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Standardized at 25 °C against chemicals whose certification is traceable to NIST. Lot standardization value, accurate to ±1 part per 1000, provided on label.

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Catalog Number: (470176-788)

Supplier: Ward's Science

Description: Drosophila melanogaster, the common fruit fly, is widely used in genetic studies. They express a number of mutations such as eye, wing, and body mutations.

Supplier: Thermo Scientific Chemicals

Description: Titanium(IV) butanolate 99+%

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Supplier: Ward's Science

Description: CAS Number: 85-83-6
Formula: C24H20N4O
Boiling Point: 260°C
Solubility: Alcohol
Synonyms: Solvent Red 24, C.I. No. 26105
Shelf Life: 36 Months

SDS

Supplier: Thermo Scientific Chemicals

Description: Cerium(IV) sulfate, anhydrous 97%

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