You Searched For: O-Benzyl-L-tyrosine

Supplier: TCI America

Description: 1-Carbobenzoxy-1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, Purity: >98.0%(GC)(T), CAS: 286961-15-7, MF: C19H26BNO4, MW: 343.23, Form: Crystal- Powder, Size: 5 G

Certificates

Catalog Number: (10415-000)

Supplier: Bioss

Description: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

Supplier: Biotium

Description: Protein phosphorylation is a fundamental event in the regulation of a large number of intracellular processes. Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be auto-phosphorylated kinases or certain cellular protein substrates. Tyrosine-phosphorylated proteins are involved in signal transduction and in the regulation of cell proliferation. Antibody to phosphotyrosine provides an excellent tool for the detection, characterization, and purification of phosphotyrosine containing proteins. This MAb shows no cross-reaction with other phosphoamino acids and is superb for multiple applications including staining of formalin/paraffin tissues.

Catalog Number: (89319-542)

Supplier: Genetex

Description: Rabbit polyclonal antibody to PTP1B (protein tyrosine phosphatase, non-receptor type 1)

Catalog Number: (10070-930)

Supplier: Prosci

Description: This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Catalog Number: (77042-282)

Supplier: ANTIBODIES.COM LLC

Description: Rabbit polyclonal antibody to Tyrosine Hydroxylase (phospho Ser31) for WB, IHC and ELISA with samples derived from Human, Mouse and Rat.

Catalog Number: (10668-720)

Supplier: Bioss

Description: May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

Catalog Number: (10668-722)

Supplier: Bioss

Description: May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

Catalog Number: (TCT1840-005G)

Supplier: TCI America

Description: CAS Number: 79831-88-2
MDL Number: MFCD02093503
Molecular Formula: C28H26O4
Molecular Weight: 426.51
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Color: White
Melting point (°C): 107

SDS

Catalog Number: (89368-058)

Supplier: Genetex

Description: Chicken polyclonal to Receptor-type tyrosine-protein phosphatase T

Catalog Number: (89147-104)

Supplier: Enzo Life Sciences

Description: Selective inhibitor of tyrosine kinase in platelet-derived growth factor (PDGF) receptor.

Catalog Number: (76117-364)

Supplier: Bioss

Description: The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene.

Catalog Number: (10456-292)

Supplier: Bioss

Description: The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

Catalog Number: (10415-002)

Supplier: Bioss

Description: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

Catalog Number: (10352-100)

Supplier: Bioss

Description: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

Catalog Number: (10427-832)

Supplier: Bioss

Description: ABI2 (Abelson interactor 2) belongs to the ABI family. The Abelson interactors are among a group of proteins that interact with Abl tyrosine kinase, a non-receptor tyrosine kinase whose activation results in the regulation of cytoskeleton function, cell growth and apoptosis in response to a variety of biological stimuli.