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Description: Rat sFLT (Soluble Fms-Like Tyrosine Kinase Receptor 1) ELISA Kit
Catalog Number: 77527-782
Supplier: AFG Bioscience


Description: Chicken polyclonal antibody to Tyrosine Hydroxylase for WB, ICC/IF, IHC, Flow Cytometry and FACS with samples derived from Human, Rat and Mouse.
Catalog Number: 77078-388
Supplier: ANTIBODIES.COM LLC


Description: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.
Catalog Number: 10413-420
Supplier: Bioss


Description: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.
Catalog Number: 10351-656
Supplier: Bioss


Description: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL?s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.
Catalog Number: 76083-412
Supplier: Bioss


Description: The proto oncogene c CBL was initially identified as the cellular homologue of v CBL oncogene that induces pre B cell lymphomas and myeloid leukemias in mice. In more recent studies CBL has been shown to be a negative regulator of tyrosine kinase signaling. The ubiquitin ligase activity of CBL leads to the degradation of tyrosine kinases, thus attenuating the signal of receptors. Targets of CBL include activated protein tyrosine kinases belonging to the Src and Syk/Zap 70 families. An additional mechanism to attenuate receptor signaling is thought to be achieved by CBL’s interaction with downstream targets of tyrosine kinases, such as PI 3K and Vav.
Catalog Number: 10351-156
Supplier: Bioss


Description: Building block for oxytocin and vasopressin analogs as carbetocin, and for structure-activity studies.
Catalog Number: B-4255.0005BA
Supplier: Bachem Americas


Description: Human ROR1 (Receptor Tyrosine Kinase Like Orphan Receptor 1) ELISA Kit
Catalog Number: 77519-088
Supplier: AFG Bioscience


Description: Fmoc-L-Tyr-(β-D-Gal(Ac)4)-OH ≥95%
Catalog Number: 76619-370
Supplier: AFG Bioscience


Description: Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily. PTPRN contains 1 tyrosine-protein phosphatase domain, is expressed in neuroendocrine cells only. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. It implicated in neuroendocrine secretory processes. It may be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. It seems to lack intrinsic enzyme activity, may play a role in the regulation of secretory granules via its interaction with SNTB2. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Catalog Number: 75788-690
Supplier: Prosci


Description: Mouse monoclonal [6G3] antibody to Dibromo-tyrosine for WB, ICC/IF, ELISA and IHC with samples derived from Species Independent.
Catalog Number: 77172-334
Supplier: ANTIBODIES.COM LLC


Description: Rabbit Polyclonal antibody to 14-3-3 beta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide)
Catalog Number: 89357-442
Supplier: Genetex


Description: CAS Number: 35677-89-5
MDL Number: MFCD00674555
Molecular Formula: C12H13NO4
Molecular Weight: 235.24
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 129
Specific rotation [a]20/D: -32 deg (C=1, MeOH)
Catalog Number: TCC2699-5G
Supplier: TCI America

SDS


Description: Rat VEGFR3 - FLT4 AccuSignal ELISA Kit
Catalog Number: 76237-498
Supplier: Rockland Immunochemical


Description: CAS Number: 18807-74-4
MDL Number: MFCD00270152
Molecular Formula: C13H20N2O2
Molecular Weight: 272.77
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Melting point (°C): 172
Catalog Number: TCC1520-001G
Supplier: TCI America

Description: Mouse Mer Receptor Tyrosine-protein Kinase Mer(MERTK) ELISA Kit
Catalog Number: 76713-004
Supplier: AFG Bioscience