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Image Unavailable-89357-406

Anti-Tubulin Mouse Monoclonal Antibody

Catalog Number: (89357-406)
Supplier: Genetex
Description: Tubulin is the major building block of microtubules. This intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules function as structural and mobility elements in mitosis, intracellular transport, flagellar movement, and in the cytoskeleton. Tubulin is a heterodimer which consists of alpha tubulin and beta tubulin; both subunits have a molecular weight of 55 kDa and share considerable homology. The most widely studied tubulins have been isolated from vertebrate brains. The microtubules can be viewed in immunofluorescent microscopy allowing for the observation of the intracellular organization of proteins that are in the form of a supramolecular structure. Distinct classes of interphase microtubules have been described in tissue culture cells. They contain post translationally modified subunits of tubulin, detyrosinated alpha tubulin (Glutubulin) or acetylated alpha tubulin. The dynamic properties of microtubules of the Tyrtubulin type studied in living cells have suggested that they turnover and grow very rapidly in vivo with most microtubules exchanging within a half-time of approximately 10 minutes. Minor subpopulations of interphase microtubules have been found to be more stable in that they resist exchange for several hours, or that they are less sensitive to microtubule disrupting drugs. The coding portion of genes encoding alpha tubulin terminates in a tyrosine codon indicating that the primary gene product is tyrosinated (Tyr-Tu). Tubulin tyrosinylation is involved in the assembly status of tubulin. A specific tubulinyl tyrosine carboxypeptidase removes the terminal tyrosine to yield an alpha tubulin terminating in a glutamic acid residue while another enzyme modifies the alpha tubulin by addition of tyrosine to the carboxy terminus to offer a potential cycle of tyrosine addition and loss.
Product Image-75877-974

QuantiChrom™ Glutamate Dehydrogenase Assay Kit, BioAssay Systems

Catalog Number: (75877-974)
Supplier: BIOASSAY SYSTEMS
Description: For quantitative determination of glutamate dehydrogenase activity.
Image Unavailable-CAAAA14176-06

α,α,α-Trifluoro-p-toluoyl chloride 97%

Supplier: Thermo Scientific Chemicals
Description: α,α,α-Trifluoro-p-toluoyl chloride 97%

Certificates

Image Unavailable-10325-098

Anti-ADAR Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10325-098)
Supplier: Bioss
Description: Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit RNAs at multiple sites (hyper-editing) or at specific sites (site-specific editing). Its cellular RNA substrates include: bladder cancer-associated protein (BLCAP), neurotransmitter receptors for glutamate (GRIA2) and serotonin (HTR2C) and GABA receptor (GABRA3). Site-specific RNA editing of transcripts encoding these proteins results in amino acid substitutions which consequently alters their functional activities. Exhibits low-level editing at the GRIA2 Q/R site, but edits efficiently at the R/G site and HOTSPOT1. Its viral RNA substrates include: hepatitis C virus (HCV), vesicular stomatitis virus (VSV), measles virus (MV), hepatitis delta virus (HDV), and human immunodeficiency virus type 1 (HIV-1). Exhibits either a proviral (HDV, MV, VSV and HIV-1) or an antiviral effect (HCV) and this can be editing-dependent (HDV and HCV), editing-independent (VSV and MV) or both (HIV-1). Impairs HCV replication via RNA editing at multiple sites. Enhances the replication of MV, VSV and HIV-1 through an editing-independent mechanism via suppression of EIF2AK2/PKR activation and function. Stimulates both the release and infectivity of HIV-1 viral particles by an editing-dependent mechanism where it associates with viral RNAs and edits adenosines in the 5'UTR and the Rev and Tat coding sequence.
Image Unavailable-TCH0991-25G

2-Hydroxy-2-methylpropiophenone ≥96.0%

Supplier: TCI America
Description: CAS Number: 7473-98-5
MDL Number: MFCD00040710
Molecular Formula: C10H12O2
Molecular Weight: 164.20
Purity/Analysis Method: >96.0% (GC)
Form: Clear Liquid
Boiling point (°C): 110
Flash Point (°C): 110
Specific Gravity (20/20): 1.08

SDS Certificates

Image Unavailable-76110-852

Anti-GPR71 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76110-852)
Supplier: Bioss
Description: The sense of taste provides animals with valuable information about the quality and nutritional value of food. There are four widely accepted categories of taste perception, sweet, bitter, salty, and sour. A controversial fifth taste, known as umami or monosodium glutamate (MSG), has also been described. A family of G protein coupled receptors are involved in taste perception, and includes T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. The T1R family consists of three members, T1R1, T1R2, and T1R3. These proteins form heterodimers, which alters the selectivity of the subunits. The T1R2 and T1R3 heterodimer functions as a receptor for sweet taste, and recognizes several sweet-tasting molecules, such as sucrose, saccharin, dulcin, and acesulfame-K. The T1R1 and T1R3 heterodimer recognizes L-amino-acids to perceive umami taste. Sweet taste transduction is carried out by two pathways. First, sucrose and other sugars activate Gas via the T1Rs, which activates adenylyl cyclase to generate cAMP. Artificial sweeteners bind to either Gbg or Gaq coupled T1Rs to activate PLCb2 and generate IP3 and DAG. Both pathways ultimately lead to neurotransmitter release. The mouse T1R3 gene maps to chromosome 4 near the Sac locus, a primary determinant of sweet preference in mice, and it is expressed in a subset of taste cells in circumvallate, foliate, and fungiform taste papillae.
Product Image-76733-126

Human Glutamate Dehydrogenase ELISA Kit

Catalog Number: (76733-126)
Supplier: ANTIBODIES.COM LLC
Description: Human Glutamate Dehydrogenase ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Glutamate Dehydrogenase in serum, plasma, tissue homogenates, and other biological fluids.
Image Unavailable-ABCA_AB62668-100UL

Anti-L Glutamate Chicken Polyclonal Antibody

Catalog Number: (ABCA_AB62668-100UL)
Supplier: Abcam
Description: Chicken polyclonal to L Glutamate.

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Product Image-76716-152

Mouse Glutamate(Glu) ELISA Kit

Catalog Number: (76716-152)
Supplier: AFG Bioscience
Description: Mouse Glutamate(Glu) ELISA Kit
Product Image-76704-748

Mouse Glutamate [NMDA] Receptor Subunit Zeta-1(GRIN1) ELISA Kit

Catalog Number: (76704-748)
Supplier: AFG Bioscience
Description: Mouse Glutamate [NMDA] Receptor Subunit Zeta-1(GRIN1) ELISA Kit
Product Image-76577-154

Human Glutamate Dehydrogenase (GDH/GLDH) ELISA Kit, AFG Bioscience

Catalog Number: (76577-154)
Supplier: AFG Bioscience
Description: Human Glutamate Dehydrogenase (GDH/GLDH) ELISA Kit, AFG Bioscience
Product Image-76711-562

Human Glutamate Receptor 1(GRIA1) ELISA Kit

Catalog Number: (76711-562)
Supplier: AFG Bioscience
Description: Human Glutamate Receptor 1(GRIA1) ELISA Kit
Product Image-ABCA_AB106289-200U

Anti-Glutamate Transporter 1 Rabbit Polyclonal Antibody

Catalog Number: (ABCA_AB106289-200U)
Supplier: Abcam
Description: Rabbit polyclonal to Glutamate Transporter 1.

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Product Image-76746-758

Human Metabotropic Glutamate Receptor 5 ELISA Kit

Catalog Number: (76746-758)
Supplier: ANTIBODIES.COM LLC
Description: Human Metabotropic Glutamate Receptor 5 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human Metabotropic Glutamate Receptor 5 in serum, plasma, tissue homogenates, and other biological fluids.
Product Image-76702-290

Rat Glutamate(Glu) ELISA Kit

Catalog Number: (76702-290)
Supplier: AFG Bioscience
Description: Rat Glutamate(Glu) ELISA Kit
Product Image-ABCA_AB281942-1MG

Anti-Metabotropic Glutamate Receptor 2/MGLUR2+Metabotropic Glutamate Receptor 3/MGLUR3 Rabbit Monoclonal Antibody [clone: EPR24635-155]

Supplier: Abcam
Description: Rabbit monoclonal [EPR24635-155] to Metabotropic Glutamate Receptor 2/MGLUR2 + Metabotropic Glutamate Receptor 3/MGLUR3 - BSA and Azide free.

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