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Product Image-89417-012

Anti-ST3GAL6 Rabbit Polyclonal Antibody

Catalog Number: (89417-012)
Supplier: Prosci
Description: ST3gal6 Antibody: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
Product Image-89323-322

Anti-NANS Rabbit Polyclonal Antibody

Catalog Number: (89323-322)
Supplier: Genetex
Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: ICC/IF, IHC-P, WB Pkg Size: 100 ul
Image Unavailable-CAGK80040

Arthrobacter ureafaciens Recombinant Sialidase A (from E. coli)

Catalog Number: (CAGK80040)
Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA
Description: The enzyme releases Alpha (2,3)-, Alpha (2,6)-, Alpha (2,8)-, and Alpha (2,9)-linked N-acetylneuraminic acid from oligosaccharides and glycoproteins. It is also capable of releasing N-glycolylneuraminic acid.
Product Image-10750-524

Anti-ST3GAL6 Rabbit Polyclonal Antibody

Catalog Number: (10750-524)
Supplier: Prosci
Description: ST3gal6 Antibody: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
Image Unavailable-76120-962

Anti-GLCNE Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76120-962)
Supplier: Bioss
Description: The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE/Mnk), or GLCNE, regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. GLCNE is required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. It is upregulated after PKC-dependent phosphorylation and is most abundantly expressed in liver and placenta. It is also expressed, to a lesser extent, in heart, brain, lung, kidney, skeletal muscle and pancreas. Defects in GLCNE are the cause of sialuria, inclusion body myopathy 2 (IBM2) and Nonaka myopathy (NM) or distal myopathy with rimmed vacuoles (DMRV). Sialuria is an autosomal dominant disorder caused by a lack of feedback inhibition of GLCNE by CMP-NeuAc, resulting in overproduction of NeuAc. It is characterized by an accumulation of free sialic acid in the cytoplasm and large quantities of neuraminic acid in the urine. Both IBM2 and NM/DMRV are autosomal recessive neuromuscular disorders characterized by adult onset, distal and proximal muscle weakness (especially in the legs) and a typical muscle pathology including filamentous inclusions and rimmed vacuoles.
Product Image-CAMK6215-06

Methyl-4-hydroxybenzoate 98.0-102.0%, GenAR® NF, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Methylparaben, NF - GenAR®

SDS Certificates

Image Unavailable-76120-964

Anti-GLCNE Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76120-964)
Supplier: Bioss
Description: The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE/Mnk), or GLCNE, regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. GLCNE is required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. It is upregulated after PKC-dependent phosphorylation and is most abundantly expressed in liver and placenta. It is also expressed, to a lesser extent, in heart, brain, lung, kidney, skeletal muscle and pancreas. Defects in GLCNE are the cause of sialuria, inclusion body myopathy 2 (IBM2) and Nonaka myopathy (NM) or distal myopathy with rimmed vacuoles (DMRV). Sialuria is an autosomal dominant disorder caused by a lack of feedback inhibition of GLCNE by CMP-NeuAc, resulting in overproduction of NeuAc. It is characterized by an accumulation of free sialic acid in the cytoplasm and large quantities of neuraminic acid in the urine. Both IBM2 and NM/DMRV are autosomal recessive neuromuscular disorders characterized by adult onset, distal and proximal muscle weakness (especially in the legs) and a typical muscle pathology including filamentous inclusions and rimmed vacuoles.
Image Unavailable-AAH63774-03

Fmoc-aspartic acid-4-methyl ester 97%

Supplier: Thermo Scientific Chemicals
Description: N-Fmoc-L-aspartic acid 4-methyl ester, 97%

SDS Certificates

Product Image-470163-076

Ester Formation Kit

Catalog Number: (470163-076)
Supplier: Ward's Science
Description: Identify the Chemical by its SMELL!

SDS


Image Unavailable-TCA0879-025ML

O-Acetylricinoleic acid methyl ester ≥80% (by GC)

Supplier: TCI America
Description: CAS Number: 140-03-4
MDL Number: MFCD00026204
Molecular Formula: C21H38O4
Molecular Weight: 354.53
Purity/Analysis Method: >80.0% (GC)
Form: Clear Liquid
Boiling point (°C): 260
Flash Point (°C): 198
Specific Gravity (20/20): 0.94

SDS

Image Unavailable-TCM2557-5G

(3,4-Dichlorophenyl)acetic acid methyl ester ≥98.0% (by GC)

Supplier: TCI America
Description: Methyl 3,4-Dichlorophenylacetate, Purity: >98.0%(GC), CAS Number: 6725-44-6, Molecular Formula: C9H8Cl2O2, Molecular Weight: 219.06, Synonyms: 3,4-Dichlorophenylacetic Acid Methyl Ester, Form: Liquid, Clear, Color: Colorless - Yellow, Size: 25G

SDS

Image Unavailable-AAH63279-06

1-Methyl-L-glutamate 98%

Supplier: Thermo Scientific Chemicals
Description: L-Glutamic acid 1-methyl ester, 98%

SDS Certificates

Image Unavailable-CAAAB21409-14

2-Nonynoic acid methyl ester 98%

Catalog Number: (CAAAB21409-14)
Supplier: Thermo Scientific Chemicals
Description: 2-Nonynoic acid methyl ester 98%

Certificates


Image Unavailable-TCM2681-1G

1-Methyl-1H-pyrazole-5-boronic acid pinacol ester ≥98.0% (by GC, titration analysis)

Catalog Number: (TCM2681-1G)
Supplier: TCI America
Description: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole, Purity: >98.0%(GC)(T), CAS Number: 847818-74-0, MF: C10H17BN2O2, MW: 208.07, Synonyms: 1-Methylpyrazole-5-boronic Acid Pinacol Ester, 4,4,5,5, Size: 1G

SDS


Product Image-76619-158

α-​Neuraminic acid, N-​acetyl-​2-​O-​(phenylmethyl)​-​, methyl ester, 4,​7,​8,​9-​tetraacetate ≥95%

Supplier: AFG BIOSCIENCE LLC
Description: α-​Neuraminic acid, N-​acetyl-​2-​O-​(phenylmethyl)​-​, methyl ester, 4,​7,​8,​9-​tetraacetate ≥95%

Image Unavailable-TCM2803-25G

Boc-L-pyroglutamic acid methyl ester ≥98.0% (by GC)

Supplier: TCI America
Description: Methyl N-(tert-Butoxycarbonyl)-L-pyroglutamate, Purity: >98.0%(GC), CAS number: 108963-96-8, MF: C11H17NO5, Molecular Weight: 243.26, Synonym: (S)-1-Boc-5-oxopyrrolidine-2-carboxylic Acid Methyl Ester, Methyl N-Boc-L-pyroglutamate, Size: 5 G

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