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Product Image-89417-242

Anti-MARVELD1 Rabbit Polyclonal Antibody

Catalog Number: (89417-242)
Supplier: Prosci
Description: MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
Image Unavailable-77436-746

Anti-HRH4 Rabbit Polyclonal Antibody

Catalog Number: (77436-746)
Supplier: Bioss
Description: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist) (By similarity).
Image Unavailable-CAPIPA5-15319

Anti-DGKZ Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-15319)
Supplier: Thermo Scientific
Description: DGKZ belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellularsignaling cascade and signal transduction.
Product Image-CAAG5185-5968

PLRP-S Capillary/Nano, Agilent Technologies

Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA
Description: Capillary and Nano Columns provide the highest level of sensitivity for even the smallest of sample sizes for small or large molecules.

Image Unavailable-76109-334

Anti-SIRT5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76109-334)
Supplier: Bioss
Description: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
Image Unavailable-10464-380

Anti-CPB2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10464-380)
Supplier: Bioss
Description: This protein belongs to a family of Zn-containing metallocarboxypeptidases specific to C-terminal lysine and arginine residues. It circulates in plasma as a zymogen with molecular weight of 55 kDa (401 amino acid residues; pI 5.0). Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. Activated carboxypeptidase B2 removes C-terminal lysine residues from fibrin, which is necessary for plasminogen binding to fibrin. This prevents plasminogen from activation into plasmin and retards the lysis of a fibrin clot. The concentration in plasma of healthy people is 5-10 ug/ml. High plasma levels were found in patients with stable angina pectoris and angiographically verified coronary artery disease. Elevated concentration in blood is considered as a risk factor for venous thrombosis. A deficiency might contribute to the severity of bleeding disorders in hemophilias A and B, and decreased levels are found in chronic liver disease.
Image Unavailable-CA82027-292

Accessories for MetroMax Q™ Shelving, Metro International

Catalog Number: (CA82027-292)
Supplier: Metropolitan Wire
Description: Add On Shelving To Existing Units Using Two Posts Instead Of Four. Join Units End-To-End, Back-To-Back, Or At Right Angles. Kit Includes One S Hook And One Corner Collar Plug. Two Kits Required Per Storage Level.
Image Unavailable-76110-392

Anti-STIL Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76110-392)
Supplier: Bioss
Description: TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.
Image Unavailable-76110-390

Anti-STIL Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76110-390)
Supplier: Bioss
Description: TAL1 disruption at 1p32, a common rearrangement in the T-cell acute lymphoblastic leukemia, usually results in the formation of a SCL interrupting locus (SIL)-TAL1 fusion product. SIL is an immediate early gene whose expression is associated with cell proliferation. The Sil protein exhibits ubiquitous expression in hematopoietic cell lines and tissues. However, Sil protein levels remain tightly regulated during the cell cycle, achieving peak levels in mitosis and diminishing on transition to G1 phase. Overexpression of Sil in primary adenocarcinomas predicts metastatic spread, especially in lung tumors with increased mitotic activity.
Image Unavailable-10465-816

Anti-RNF144B Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10465-816)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
Image Unavailable-10465-822

Anti-RNF144B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10465-822)
Supplier: Bioss
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se.Tissue specificity: Broadly expressed, with lowest levels in brain and thymus, and highest levels detectable in heart, ovary and testis.
Image Unavailable-NSQCI-072

Effluent Level Inorganics Wastewater Standard, NSI

Supplier: SPEX CERTIPREP LLC
Description: Whole volume standard

Small Business Enterprise Minority or Woman-Owned Business Enterprise

Image Unavailable-CA80601-896

Overnight Express™ Autoinduction System 1, MilliporeSigma

Supplier: MilliporeSigma
Description: The Overnight Express™ Autoinduction System 1 enables high-level protein expression without the need to monitor cell growth or add an inducer during the growth period.

Certificates

Image Unavailable-10426-578

Anti-ANGPTL3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10426-578)
Supplier: Bioss
Description: Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
Image Unavailable-76109-708

Anti-IQCG Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76109-708)
Supplier: Bioss
Description: IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn -helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
Image Unavailable-10462-078

Anti-DDX5 Rabbit Polyclonal Antibody

Catalog Number: (10462-078)
Supplier: Bioss
Description: p68 RNA helicase is a nuclear protein that exhibits RNA-dependent ATPase activity. Phosphorylation by protein kinase C inhibits p68 RNA helicase activity. p68 RNA helicase appears to play a role in organ differentiation during development. Furthermore, p68 RNA helicase is expressed in early neural development and in various mesodermal tissues in a number of different chordate embryos. At the cellular level, the expression levels of p68 RNA helicase increases in serum-induced quiescent cell lines. p68 RNA helicase may function as a coactivator for estrogen receptor alpha. Additionally, p68 RNA helicase associates with transcriptional coactivators CBP and p300. p68 RNA helicase localizes to the nucleus under normal conditions. During late telophase, p68 RNA helicase and fibrillarin colocalize to nascent nucleoli. p68 RNA helicase may function as a heterodimer with p72 RNA helicase.
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