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Catalog Number: (89147-664)
Supplier: Enzo Life Sciences
Description: Represents a class of natural compounds, which inhibit proliferation in eukaryotes by blocking nuclear export. As potent as leptomycin B (Prod. No. ALX-380-100) and specific for G1/S checkpoint. Cytotoxic secondary metabolite (IC50=50pg/ml in mouse cell line L929) that arrests tumor cells in the G1 phase at remarkably low concentrations (50pg/ml in HeLa cell line KB3.1). Inhibits the binding between the nuclear export signal (NES) of proteins and the chromosome maintenance region protein (CRM1). Anticancer compound. Belongs to the family of orphan ligands which include polyketides like leptomycin B, callystatin A and other related compounds.


Supplier: Enzo Life Sciences
Description: Cathepsin substrate

Catalog Number: (89153-098)
Supplier: Enzo Life Sciences
Description: TLR9 ligand.


Catalog Number: (89165-230)
Supplier: Enzo Life Sciences
Description: For use in deubiquitinylating enzyme assays and linear polyubiquitin binding studies.


Catalog Number: (89155-336)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG1


Supplier: Enzo Life Sciences
Description: A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.

Supplier: Enzo Life Sciences
Description: TRPV1 antagonist

Catalog Number: (89144-392)
Supplier: Enzo Life Sciences
Description: Produced in <i>E. coli.</i>


Catalog Number: (89145-306)
Supplier: Enzo Life Sciences
Description: Peroxisomes are single membrane organelles which are involved in many important biochemical pathways and are found in almost all eukaryotic cells. Various toxins including phenols, alcohols, and aldehydes are targeted for modification by peroxisomes. Long chain fatty acid metabolism via β-oxidation is also mediated by this organelle. Loss of peroxisomal functions may result in diseases such as Zellweger syndrome, hyperpipecolic acidemia, neonatal adrenoleukodystrophy, and infantile Refsums disease. Peroxisomal membrane protein 70 (PMP70) is an abundant, integral membrane protein of the peroxisome. This protein is induced by treatment with hypolipidemic agents in parallel with peroxisome proliferation and stimulation of the peroxisomal β-oxidation enzymes.


Supplier: Enzo Life Sciences
Description: Host: Rabbit

Catalog Number: (89148-852)
Supplier: Enzo Life Sciences


Catalog Number: (89161-654)
Supplier: Enzo Life Sciences
Description: Inhibitor of TNF-alpha processing


Catalog Number: (89142-028)
Supplier: Enzo Life Sciences
Description: Immunoglobulin M (IgM) is an immunoglobulin expressed initially on the surface of B-cells as a monomer of two mu heavy chains and two light chains. Following B-cell activation, IgM is secreted in its pentameric form, consisting of five IgM molecules joined at the base of the Fc domain by a J chain. IgM is the first Immunoglobulin expressed following infection.


Catalog Number: (89166-054)
Supplier: Enzo Life Sciences
Description: Lipid dye

Catalog Number: (89165-678)
Supplier: Enzo Life Sciences
Description: Host: Mouse, Isotype: IgG2b


Catalog Number: (89157-842)
Supplier: Enzo Life Sciences
Description: Deprenyl inhibits apoptosis and displays neuroprotective effects in a variety of in vitro and in vivo systems. In vivo it rescues nigral dopaminergic neurons after systemic MPTP treatment. In vitro it rescues PC12 cells from apoptotic cell death induced by trophic withdrawal. The putative target responsible for the anti-apoptotic effects is glyceraldehyde-3-phosphate dehydrogenase. Deprenyl also inhibits monoamine oxidase-B, which is not involved in its anti-apoptotic mechanism. Parkinson’s disease therapeutic.


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