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Image Unavailable-10371-712

Anti-HSPB8 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10371-712)
Supplier: Bioss
Description: Hsp22 (HSPB8) is a 196-amino acid protein that contains a central portion homologous to a highly conserved HSP-alpha crystallin domain common to all the small heat shock protein (HSP20) family members. Hsp22 is a monomeric protein which interacts with HSPB1. It displays temperature-dependent chaperone activity. The highest abundance of Hsp22 is in skeletal muscle, heart, and placenta. Mutations in the HSPB8 gene are associated with the inherited peripheral neuropathies, autosomal dominant distal hereditary motor neuropathy type IIA (dSMA) and axonal Charcot-Marie-Tooth disease type 2L (CMT2L).
Image Unavailable-10491-082

Anti-FRG2B Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10491-082)
Supplier: Bioss
Description: Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Product Image-10105-058

Anti-DVL1 Rabbit Polyclonal Antibody

Catalog Number: (10105-058)
Supplier: Prosci
Description: DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Product Image-89351-144

Anti-PMP22 Rabbit Polyclonal Antibody

Catalog Number: (89351-144)
Supplier: Genetex
Description: PMP 22 is a 22 kDa glycoprotein expressed in the compact myolin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
Product Image-470007-534

Geoblox Volcano Block Models

Catalog Number: (470007-534)
Supplier: JOHN HAROLD KOONZ
Description: Build models to study this important geological feature.
Image Unavailable-10482-710

Anti-LRRC2 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10482-710)
Supplier: Bioss
Description: The leucine-rich repeat-containing protein 2 (LRRC2) is a 371 amino acid protein that contains 9 LRR repeats. The gene encoding LRRC2 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Image Unavailable-10482-714

Anti-LRRC2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10482-714)
Supplier: Bioss
Description: The leucine-rich repeat-containing protein 2 (LRRC2) is a 371 amino acid protein that contains 9 LRR repeats. The gene encoding LRRC2 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Product Image-10075-422

Anti-NEFL Chicken Polyclonal Antibody

Catalog Number: (10075-422)
Supplier: Prosci
Description: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.
Image Unavailable-10482-720

Anti-LRRC2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10482-720)
Supplier: Bioss
Description: The leucine-rich repeat-containing protein 2 (LRRC2) is a 371 amino acid protein that contains 9 LRR repeats. The gene encoding LRRC2 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Image Unavailable-10491-086

Anti-FRG2B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10491-086)
Supplier: Bioss
Description: Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Product Image-470002-352

Crime Scene Investigations

Catalog Number: (470002-352)
Supplier: John Wiley & Sons
Description: Pam Walker and Elaine Wood
Image Unavailable-76108-644

Anti-LRRC2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76108-644)
Supplier: Bioss
Description: The leucine-rich repeat-containing protein 2 (LRRC2) is a 371 amino acid protein that contains 9 LRR repeats. The gene encoding LRRC2 maps to chromosome 3, which encodes over 1,100 genes. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Product Image-89500-392

General Purpose Unstirred Digital Water Bath Range, 230 V, Grant Instruments

Supplier: GRANT USA INC.
Description: General Purpose Water Baths with stable temperature control, simple interface and fast heat-up. Choose from four models each with base tray and lid included as standard.
The JB Nova general purpose unstirred water bath range benefits from key features such as the newly incorporated Set and Forget™ technology with advanced dry start and run dry protection. These are in addition to the standard features including an element free tank, user calibration, front panel lock and drain tap on sizes 12L and above

Irregular Voltage CSA Certified

Image Unavailable-10481-820

Anti-LHPP Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10481-820)
Supplier: Bioss
Description: LHPP, also known as HDHD2B, is a 270 amino acid protein that exists as a homodimer and is a member of the HAD-like hydrolase superfamily. Expressed in liver, kidney and moderately in brain, LHPP is encoded by a gene located on 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Image Unavailable-77439-510

Anti-HOXD10 Rabbit Polyclonal Antibody

Catalog Number: (77439-510)
Supplier: Bioss
Description: This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Image Unavailable-10093-224

Anti-RAB7A Rabbit Polyclonal Antibody

Catalog Number: (10093-224)
Supplier: Proteintech
Description: RAB7A, also named as RAB7, belongs to the small GTPase superfamily and Rab family. It is involved in late endocytic transport. RAB7A contributes to the maturation of phagosomes (acidification). Defects in RAB7A are the cause of Charcot-Marie-Tooth disease type 2B (CMT2B). This antibody is specific to RAB7A.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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