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Catalog Number: (10664-316)
Supplier: Bioss
Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.


Catalog Number: (10664-310)
Supplier: Bioss
Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.


Catalog Number: (77522-890)
Supplier: AFG Bioscience
Description: Rat IREB2 (Iron Responsive Element Binding Protein 2) ELISA Kit


Catalog Number: (CA80051-292)
Supplier: MilliporeSigma
Description: Serum copper transport and iron-oxidizing protein. Plays an important role in antioxidant protection against organic and inorganic oxygen radicals generated by iron and ascorbate. Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Catalog Number: (76117-490)
Supplier: Bioss
Description: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.


Catalog Number: (10664-314)
Supplier: Bioss
Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.


Catalog Number: (10490-756)
Supplier: Bioss
Description: Mitoferrin1, SLC25A37, belongs to the mitochondrial carrier family and contains 3 Solcar repeats. It is a mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells and plays an essential role in heme biosynthesis.


Catalog Number: (76110-756)
Supplier: Bioss
Description: Mitoferrin1, SLC25A37, belongs to the mitochondrial carrier family and contains 3 Solcar repeats. It is a mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells and plays an essential role in heme biosynthesis.


Catalog Number: (470202-852)
Supplier: Humboldt Manufacturing
Description: Bases are cast iron with black enamel finish. Rods are zinc plated steel and threaded to fit into the base.


Supplier: Wards
Description: This cast iron base features threads for rods sized 1/2 - 13.

Supplier: United Scientific Supplies
Description: Tip-free stability for experiments.

Catalog Number: (89321-330)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to Pirin (pirin (iron-binding nuclear protein))


Catalog Number: (CA1.14403.0001)
Supplier: MilliporeSigma
Description: Iron Test Method: colorimetric with color card and comparator block with long test tubes 0.01 - 0.02 - 0.03 - 0.04 - 0.06 - 0.08 - 0.10 - 0.15 -0.20 mg/l Fe MColortest*

Catalog Number: (10491-920)
Supplier: Bioss
Description: Friedreich ataxia is a progressive neurodegenerative disorder caused by loss of function mutations in the frataxin gene. The human frataxin gene maps to chromosome 9q13.The frataxin gene encodes a mitochondrial protein of the same name. Frataxin assembles into a stable homopolymer with iron-binding capabilities. When expressed in E. Coli human frataxin binds iron atoms at a rate of 10 iron atoms per 1 molecule of the frataxin polymer. Thus, frataxin appears to function in some capacity for iron-storage for the mitochondria. Frataxin may also function as an activator of oxidative phosphorylation to increase mitochondrial membrane potential and elevate cellular ATP. Frataxin is expressed in tissues with high metabolic activity including heart, liver and brown fat.


Catalog Number: (CA1.12084.0001)
Supplier: MilliporeSigma
Description: Used to detect free ionic iron using the Prussian blue method in cells and tissues

Supplier: Bico
Description: Iron alloy replacement plate, for use with Type UA Pulverizer (24253-000).

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