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Image Unavailable-10452-576

Anti-SCN8A Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10452-576)
Supplier: Bioss
Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Image Unavailable-10452-338

Anti-SCN8A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10452-338)
Supplier: Bioss
Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Image Unavailable-470130-630

9780133223538 PM13 NA INQWRMUP LIFE 3 BX

Catalog Number: (470130-630)
Supplier: Avantor
Description: 9780133223538 PM13 NA INQWRMUP LIFE 3 BX
Image Unavailable-89363-462

Anti-Avian Influenza Neuraminidase Rabbit Polyclonal Antibody

Catalog Number: (89363-462)
Supplier: Genetex
Description: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.
Image Unavailable-76118-616

Anti-SCN8A Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76118-616)
Supplier: Bioss
Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Image Unavailable-89360-778

Anti-GLB1 Mouse Monoclonal Antibody

Catalog Number: (89360-778)
Supplier: Genetex
Description: Beta galactosidase is coded by a gene (lac z) in the lac operon of Escherichia coli. It is a metalloenzyme that splits lactose into glucose and galactose. It hydrolyzes terminal, non-reducing beta-D-galactose residues in beta-D-galactosides. Activation by cations seems to be substrate dependent. K+, Na+, NH4+, Rb+, Cs+ and Mn++ all activate enzyme activity based upon the substrate used.
Image Unavailable-10452-582

Anti-SCN8A Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10452-582)
Supplier: Bioss
Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Image Unavailable-89367-122

Anti-Avian Influenza Neuraminidase Rabbit Polyclonal Antibody

Catalog Number: (89367-122)
Supplier: Genetex
Description: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.
Product Image-89160-682

Kavain (+/-) ≥98%

Supplier: Enzo Life Sciences
Description: Kavain is one constituent of kava-kava, an herbal drug of the South Pacific islands, which displays anti-convulsive, anxiolytic, analgesic and muscle relaxing properties. Kavain inhibits voltage-dependent Na+ channels in rat CA1 hippocampal neurons. It displays protective effects in the MPTP mouse model of Parkinson's disease but potentiates NMDA toxicity in the developing hippocampus.

Product Image-470300-276

Aniline Blue

Supplier: Ward's Science
Description: CAS Number: 28631-66-5
Formula Weight: 737.73
Formula: C32H25N3Na2O9S3
Hazard Info: Irritant
Boiling Point (°C): Decomposes
Synonyms: Acid Blue 22, C.I. No. 42755
Shelf Life (months): 36
Storage: Green

SDS

Image Unavailable-470130-530

9780133211290 PM13 NA LIFE KIT 6 BX

Catalog Number: (470130-530)
Supplier: Avantor
Description: 9780133211290 PM13 NA LIFE KIT 6 BX
Image Unavailable-470130-672

9780133223507 PM13 NA LBNVST RF LIFE 2BX

Catalog Number: (470130-672)
Supplier: Avantor
Description: 9780133223507 PM13 NA LBNVST RF LIFE 2BX
Image Unavailable-103006-234

Human C-peptide (57-87)

Catalog Number: (103006-234)
Supplier: Anaspec Inc
Description: C-peptide is cleaved from proinsulin, stored in secretory granules, and eventually released into the bloodstream in amounts equimolar with those of insulin. The measurement of the C-peptide is an important test for the beta-cell function. In the red blood cells of type 2 diabetic patients, Na+,K+ ATPase activity is strongly related to blood C-peptide levels. C-peptide signal transduction in human renal tubular cells involves the activation of phospholipase C and PKC-delta and PKC-varepsilon, as well as RhoA, followed by phosphorylation of ERK1/2 and JNK and a parallel activation of Akt. C-peptide shows specific binding to a G-protein-coupled membrane binding site, resulting in Ca2+ influx, activation of mitogen-activated protein kinase signalling pathways and stimulation of Na+, K+ ATPase and endothelial nitric oxide synthase.
Sequence: EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
MW: 3020.3 Da
% Peak area by HPLC: 95
Storage condition: -20° C
Product Image-ABCA_AB287789-96TE

Norepinephrine ELISA Kit

Catalog Number: (ABCA_AB287789-96TE)
Supplier: Abcam
Description: Norepinephrine ELISA kit is a competitive ELISA designed to quantify norepinephrine/noradrenaline (NA) with a sensitivity of <9.375 pg/ml. - Wide dynamic range - quantifies 15.625 - 1000 pg/ml. Broad sample compatibility - works with serum, plasma, tissue homogenates, cell culture supernatants, and other biological fluids. Assay platform - microplate (12×8-well strips) for easy setup and reliable results.

New Product


Product Image-470300-788

Congo Red

Supplier: Ward's Science
Description: CAS Number: 573-58-0
Formula Weight: 696.68
Formula: C32H22N6Na2O6S2
Hazard Info: Toxic
Solubility: Water and Alcohol
Synonyms: Direct Red 28, C.I. No. 22120, Congo Red Stain, Congo Red Biostain
Shelf Life (months): 36
Storage: Green

SDS

Image Unavailable-10458-740

Anti-BANK1 Rabbit Polyclonal Antibody

Catalog Number: (10458-740)
Supplier: Bioss
Description: Members of the Ankyrin family of proteins mediate the attachment of integral membrane proteins to the cytoskeleton. ANK1, ANK2 and ANK3 genes encode for the proteins in this family, Ankyrin-1 (also designated Ankyrin R), Ankyrin B and Ankyrin G, respectively. The proteins are structured similarly each composed of an N-terminal domain with multiple ankyrin repeats, a highly conserved central spectrin binding domain, and C-terminal regulatory domains which are susceptible to the most variance. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Ankyrin B, or brain Ankyrin is predominantly expressed in the plasma membrane of neurons as well as glial cells throughout the brain. Two transcripts have been described with alternative splicing resulting in additional isoforms. The Ankyrin B protein associates with the spectrin-actin network, mediates axon fasciculation, and stabilizes axon bundles. Ankyrin B is required for coordinated assembly of Na/Ca exchanger, Na/K ATPase, and inositol trisphosphate (InsP(3)) receptor at transverse-tubule/sarcoplasmic reticulum sites in cardiomyocytes.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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