You Searched For: Fmoc-Tyr(tBu)

Supplier: Bachem Americas

Description: The peptide CDPGYIGSR amide, which comprises residues 925-933 of the laminin B1 chain, inhibited both angiogenesis and solid tumor growth.

Supplier: Bachem Americas

Description: VYV was used as internal standard peptide in urine analysis by LC-MS. The tripeptide is used in peptide standard mixtures for HPLC.

Catalog Number: (TCB1640-5G)

Supplier: TCI America

Description: CAS Number: 3978-80-1
MDL Number: MFCD00037179
Molecular Formula: C14H19NO5
Molecular Weight: 281.31
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 135
Specific rotation [a]20/D: 3 deg (C=2, AcOH)

Catalog Number: (M-2475.0001BA)

Supplier: Bachem Americas

Description: Abz-AFAFDVY(NO₂)D, a fluorogenic (FRET) substrate for endoproteinase AspN, Asp-specific proteases from Staphylococcus aureus, Bacillus licheniformis and Streptomyces griseus.

Catalog Number: (76708-436)

Supplier: AFG BIOSCIENCE LLC

Description: Human FMS-like tyrosine kinase 3(Flt3) ELISA Kit

Catalog Number: (10350-450)

Supplier: Bioss

Description: Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in trafficking and clathrin-mediated endocytosis through binding to epidermal growth factor receptor (EGFR) and clathrin. Binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR, thereby contributing to the accumulation of EGFR at the limiting membrane of early endosomes. Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. May be involved both in adult synaptic function and plasticity and in brain development. Activates AKT1 by phosphorylating it on 'Tyr-176'. Phosphorylates AR on 'Tyr-267' and 'Tyr-363' thereby promoting its recruitment to androgen-responsive enhancers (AREs). Phosphorylates WWOX on 'Tyr-287'. Phosphorylates MCF2, thereby enhancing its activity as a guanine nucleotide exchange factor (GEF) toward Rho family proteins. Contributes to the control of AXL receptor levels. Confers metastatic properties on cancer cells and promotes tumor growth by negatively regulating tumor suppressor such as WWOX and positively regulating pro-survival factors such as AKT1 and AR.

Catalog Number: (10416-776)

Supplier: Bioss

Description: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.

Catalog Number: (89367-990)

Supplier: Genetex

Description: Recognises the alpha subunit of tubulin, specifically binding to so called Tyr-Tubulin, which is produced by post translational modification of tubulin. The epitope recognised by this antibody has been extensively studied and would appear to be a linear sequence requiring an aromatic residue at the C terminus, with the two adjacent amino acids being negatively charged (represented by Gly-Gly-Tyr in Tyr-Tubulin). The antibody has been used in epitope tagging procedures to detect proteins tagged with a C-terminal Gly-Gly-Phe epitope. These sequence requirements have been reported to result in some cross-reactivity with other proteins in certain circumstances, including E. Coli rec A and oxidized actin.

Catalog Number: (10416-778)

Supplier: Bioss

Description: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.

Catalog Number: (76712-688)

Supplier: AFG BIOSCIENCE LLC

Description: Mouse Receptor Tyrosine-protein Kinase erbB-2(HER-2) ELISA Kit

Supplier: Bachem Americas

Description: PEG acrylate-based hydrogels have been modified with the RGD peptide YRGDS to improve their biocompatibility. YRGDS can be radioiodinated.

Catalog Number: (89156-646)

Supplier: Enzo Life Sciences

Description: A highly potent, cell-permeable proteasome inhibitor that targets all individual active subunits with comparable affinity. This extended peptide-based inhibitor can be radioiodinated, allowing detection of labeled subunits by autoradiography.

Catalog Number: (76706-160)

Supplier: AFG BIOSCIENCE LLC

Description: Mouse Receptor Tyrosine-protein Kinase erbB-3(ERBB3) ELISA Kit

Supplier: TCI America

Description: CAS Number: 621-44-3
MDL Number: MFCD00007123
Molecular Formula: C9H10N2O5
Molecular Weight: 226.19
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 224
Specific rotation [a]20/D: 3 deg (C=1, 1mol/L HCl)

SDS Certificates

Catalog Number: (N-1960.1000BA)

Supplier: Bachem Americas

Description: See also the Asp derivatives N-1425 and N-1430, and Z-YVAD-FMK (N-1595).

Catalog Number: (76101-458)

Supplier: Bioss

Description: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.