You Searched For: Fmoc-Lys(Dnp)-OH


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Catalog Number: (B-2885.1000BA)
Supplier: Bachem Americas
Description: Sequence: Fmoc-Lys(Dnp)-OH


Supplier: Thermo Scientific Chemicals
Description: e-2,4-Dinitrophenyl-N^a-Fmoc-L-lysine, 98%
Supplier: Bachem Americas
Description: FRET substrate for angiotensin-converting enzyme 2 (ACE2). Mca-APK(Dnp)-OH is used for monitoring the activity of the enzyme in plasma, urine, heart, and lungs.

Supplier: Bachem Americas
Description: See also M-2460 and M-2465.

Supplier: Bachem Americas
Description: FITC-YVADAPK(Dnp) is a specific FRET substrate for the determination of caspase-1 and caspase-1 like enzyme activities. Cleavage of FITC-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay. It is useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active using this substrate. See also our reference substance M-2280.

Supplier: Bachem Americas
Description: Abz-GIVRAK(Dnp), a very efficient and selective FRET substrate for human cathepsin B (Km = 5.9 µM, kcat = 43 s⁻¹, kcat/Km = 7288 mM⁻¹s⁻¹). The kcat/Km values for cathepsin K, L, V, X, and cruzain were 133.3, 100, 32, 17, and 75 mM⁻¹s⁻¹, respectively.

Catalog Number: (M-2195.0001BA)
Supplier: Bachem Americas
Description: Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.


Catalog Number: (M-2420.0001BA)
Supplier: Bachem Americas
Description: Fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF.


Supplier: Bachem Americas
Description: Excellent angiotensin I-converting enzyme (ACE) FRET substrate with a Km value of 4.0 µM and a kcat value of 210 s⁻¹. Alves et al. developed a continuous fluorescent assay using Abz-FRK(Dnp)P for the determination of ACE activity in plasma and tissue.

Catalog Number: (B-2995.0001BA)
Supplier: Bachem Americas
Description: Sequence: Fmoc-Dap(Dnp)-OH


Supplier: Bachem Americas
Description: Substrate V, Mca-RPPGFSAFK(Dnp), is a very sensitive internally quenched fluorescent substrate for endothelin-converting enzyme-1 (ECE-1) a membrane-bound zinc metallopeptidase that is related to neprilysin in amino acid sequence. The kcat/Km value for the hydrolysis by ECE-1 was 1.9 x 10⁷ M⁻¹s⁻¹ and 1.7 x 10⁶ M⁻¹s⁻¹ for the hydrolysis by neprilysin. This FRET substrate was hydrolyzed rapidly by stromelysin 1 (MMP-3) with kcat/Km= 218000 M⁻¹s⁻¹ and very slowly by gelatinase B (MMP-9) (kcat/Km= 10100 M⁻¹s⁻¹). There was no hydrolysis by MMP-1 and MMP-2. Mca-RPPGFSAFK(Dnp) has also found use as substrate for insulin-degrading enzyme (IDE) and ACE2.

Supplier: Bachem Americas
Description: Sequence: H-Lys(Fmoc)-OH

Supplier: Bachem Americas
Description: Sequence: Fmoc-Lys(biotinyl)-OH

Supplier: Bachem Americas
Description: Sequence: Fmoc-Lys(Fmoc)-OH

Supplier: Bachem Americas
Description: Sequence: Fmoc-Lys(Aloc)-OH

Supplier: Bachem Americas
Description: Sequence: Fmoc-Lys(ivDde)-OH

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