You Searched For: Fmoc-L-propargylglycine

Catalog Number: (TCA1833-100MG)

Supplier: TCI America

Description: CAS Number: 878483-02-4
Molecular Formula: C35H38N4O9
Molecular Weight: 658.71
Purity/Analysis Method: >92.0% (HPLC)
Form: Crystal
Specific rotation [a]20/D: 89 deg (C=1, CHCl3)
Storage Temperature: <0°C

SDS

Supplier: Bachem Americas

Description: Ramage resin is highly suitable for the preparation of peptide amides by the Fmoc-strategy and is recommended for C-terminal Phe, Tyr and Ile. Cleavage has been performed with 50 % TFA in CH₂Cl₂ or 95% aqueous TFA. Scavengers may be required. Tricyclic amide linker resin has been used for the synthesis of fluorogenic substrates for continuous assay of aminopeptidase P. Bachem additionally offers the Ramage amide linker (Q-2745) to be coupled to other types of carrier resin.

Supplier: TCI America

Description: CAS Number: 84418-43-9
MDL Number: MFCD00270532
Molecular Formula: C15H13NO2
Molecular Weight: 239.27
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 204

SDS Certificates

Catalog Number: (D-2125.0001BA)

Supplier: Bachem Americas

Description: Useful for the synthesis of peptide amides using Fmoc strategy. Cleavage has been performed with 50 % TFA in CH₂Cl₂ or 95% aqueous TFA. Scavengers may be required.

Supplier: TCI America

Description: CAS Number: 35661-51-9
MDL Number: MFCD00239419
Molecular Formula: C15H14N2O2
Molecular Weight: 254.29
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 171
Storage Temperature: 0-10°C

SDS Certificates

Supplier: TCI America

Description: CAS Number: 120791-76-6
Molecular Formula: C23H27NO5
Molecular Weight: 397.47
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Melting point (°C): 100
Specific rotation [a]20/D: -4 deg (C=1, CHCl3)
Storage Temperature: 0-10°C

SDS Certificates

Supplier: Bachem Americas

Description: Diphenyldiazomethane was used industrially for producing benzhydryl esters (diphenylmethyl esters) of β-lactam antibiotics. This "polymeric diphenyldiazomethane" readily reacts with carboxylic acids, e.g. Fmoc-amino acids, which need not to be activated. Products can be cleaved from this very acid-sensitive resin derivative with 1-5 % TFA in dichloromethane.

Catalog Number: (TCA1832-100MG)

Supplier: TCI America

Description: CAS Number: 195976-07-9
Molecular Formula: C36H40N4O9
Molecular Weight: 672.74
Purity/Analysis Method: >97.0% (HPLC)
Form: Crystal
Specific rotation [a]20/D: 114 deg (C=1, CHCl3)
Storage Temperature: <0°C

SDS

Catalog Number: (B-3930.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Catalog Number: (B-4085.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Supplier: Bachem Americas

Description: A very acid sensitive resin suitable for the synthesis of protected peptide fragments by the Fmoc-strategy. ClTrt resin is in particular suitable for the preparation of C-terminal prolyl and cysteinyl peptides (please see 2-Chlorotrityl Chloride Resin-Linked Amino Acids). Release from this resin is achieved by using 1-50 % TFA in CH₂Cl₂ containing 8 % triisopropylsilane, AcOH/CF₃CH₂OH/CH₂Cl₂, 0.5 % TFA or hexafluoroisopropanol/CH₂Cl₂. ClTrt resin has been used in cyclization reactions under Heck reaction conditions, the solid phase synthesis of β-peptides via the Arndt-Eistert homologation of Fmoc-protected amino acid diazoketones and in Mannich reactions of alkynes, secondary amines and aldehydes in the presence of a copper (I) salt affording the corresponding aminomethylalkynyl adducts. 2-Chlorotrityl resin is highly suitable for the synthesis of peptide alcohols, e.g., peptaibols, and peptide ω-aminoalkylamides.

Catalog Number: (B-4055.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Catalog Number: (B-4270.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Catalog Number: (B-4300.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Catalog Number: (B-4285.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Catalog Number: (B-4275.0005BA)

Supplier: Bachem Americas

Description: These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.