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Melatonin, Calbiochem

Catalog Number: (CA80057-004)
Supplier: MilliporeSigma
Description: A hormone that has been postulated as the mediator of photic-induced anti-gonadotropic activity in photoperiodic mammals. Counteracts the apoptotic effects of etoposide in bone marrow cells.

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Image Unavailable-10427-034

Anti-SERINC3 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10427-034)
Supplier: Bioss
Description: TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
Image Unavailable-75789-178

Human Recombinant Heat Shock beta 11 (from E. coli)

Catalog Number: (75789-178)
Supplier: Prosci
Description: Heat Shock Protein beta -11 (HSPB11) is a stress-responsive protein that is required to deal with proteotoxic stresses. HSPB11 is composed of an IFT complex B composed of IFT88, IFT57, TRAF3IP1, IFT52, IFT27, HSPB11 and IFT20 and is detected in placenta. HSPB11 has beeb shown to form oligomeric complexes and prevent the aggregation of in vitro denaturated aldolase and glyceraldehyde-3-phosphate dehydrogenase in accordance with the chaperone model of HSPB1 and HSPB5. HSPB11 overexpression protected against etoposide-induced cell death that correlated with a decreased release of mitochondrial Cytochrome C into the cytosol. Inhibition of HSP90 function completely abrogated the protective effect of HSPB11. This data suggests that at least in the case of HSPB11, interaction with other chaperone machines besides HSPA1A may contribute to functional specificity and cellular functioning.
Image Unavailable-10427-042

Anti-SERINC3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10427-042)
Supplier: Bioss
Description: TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
Image Unavailable-10427-040

Anti-SERINC3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10427-040)
Supplier: Bioss
Description: TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
Image Unavailable-76081-406

Anti-SERINC3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76081-406)
Supplier: Bioss
Description: TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
Product Image-89357-904

Anti-BIRC7 Rabbit Polyclonal Antibody

Catalog Number: (89357-904)
Supplier: Genetex
Description: The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq]
Image Unavailable-10427-038

Anti-SERINC3 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10427-038)
Supplier: Bioss
Description: TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
Image Unavailable-ABCA_AB120227-100M

ETOPOSIDE, TOPOISOMERASE AB120227-100MG

Catalog Number: (ABCA_AB120227-100M)
Supplier: Abcam
Description: ETOPOSIDE, TOPOISOMERASE AB120227-100MG

New Product


Image Unavailable-CA75983-502

LYSATE HELA WH CEL ETOPOSIDE STIMU 500UG

Catalog Number: (CA75983-502)
Supplier: Rockland Immunochemical
Description: LYSATE HELA WH CEL ETOPOSIDE STIMU 500UG
Image Unavailable-ABCA_AB120227-25MG

ETOPOSIDE, TOPOISOMERASE AB120227-25MG

Catalog Number: (ABCA_AB120227-25MG)
Supplier: Abcam
Description: ETOPOSIDE, TOPOISOMERASE AB120227-25MG

New Product


Image Unavailable-CA75983-494

EXTRACT NUC HELA CELL ETOPOSIDE 200UG

Catalog Number: (CA75983-494)
Supplier: Rockland Immunochemical
Description: EXTRACT NUC HELA CELL ETOPOSIDE 200UG
Product Image-89156-948

Decylubiquinone ≥98% (by TLC)

Supplier: Enzo Life Sciences
Description: MPTP inhibitor

Product Image-89161-240

Z-Val-Ala-Asp(OMe)-Fluoromethyl Ketone

Catalog Number: (89161-240)
Supplier: Enzo Life Sciences
Description: Caspase inhibitor
Product Image-89151-204

IM-54 ≥98% (by HPLC)

Supplier: Enzo Life Sciences
Description: Cell permeable inhibitor of necrosis

Product Image-89151-300

Necrox-5™ methanesulfonate

Supplier: Enzo Life Sciences
Description: Necrosis inhibitor.

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