You Searched For: D-erythro-Sphingosine


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Catalog Number: (89148-714)
Supplier: Enzo Life Sciences


Catalog Number: (TCS0874-25MG)
Supplier: TCI America
Description: CAS Number: 123-78-4
MDL Number: MFCD00036751
Molecular Formula: C18H37NO2
Molecular Weight: 299.50
Purity/Analysis Method: >96.0% (GC)
Form: Crystal
Color: White
Melting point (°C): 74
Specific rotation [a]20/D: -2 deg (C=1, CHCl3)
Storage Temperature: <0°C

Catalog Number: (89148-704)
Supplier: Enzo Life Sciences
Description: PKC inhibitor


Catalog Number: (CAAAJ63584-MB)
Supplier: Thermo Scientific Chemicals
Description: D-erythro-Sphingosine is used to inhibit protein kinase C and calmodulin-dependent enzymes, induces apoptosis. And also used to constituent of cell membranes.

Supplier: Enzo Life Sciences
Description: Sphingosine kinase inhibitor

Supplier: Enzo Life Sciences
Description: Sphingosine precursor

Catalog Number: (89157-674)
Supplier: Enzo Life Sciences
Description: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.


Catalog Number: (89164-606)
Supplier: Enzo Life Sciences
Description: Endogenous signaling molecule.


Supplier: Enzo Life Sciences
Description: A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

Catalog Number: (10343-422)
Supplier: Bioss
Description: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.


Catalog Number: (10343-694)
Supplier: Bioss
Description: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.


Catalog Number: (10343-688)
Supplier: Bioss
Description: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.


Catalog Number: (89139-334)
Supplier: Biotium
Description: NBD C6-ceramide (6-((N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)hexanoyl)sphingosine) has been used for following sphingolipid metabolism in cells, and as a selective stain for the Golgi apparatus in live and fixed cells.


Catalog Number: (10343-686)
Supplier: Bioss
Description: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.


Catalog Number: (10343-684)
Supplier: Bioss
Description: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.


Catalog Number: (76082-562)
Supplier: Bioss
Description: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.


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