N-Hexanoyl-D-erythro-sphingosine ≥98% (by TLC)

Supplier: Enzo Life Sciences

BML-SL110-0005 BML-SL110-0025

89164-576EA 132.72 CAD

89164-576 89164-578

N-Hexanoyl-D-erythro-sphingosine ≥98% (by TLC)

N-Hexanoyl-D-erythro-sphingosine

A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

Cell-permeable ceramide analog

White waxy solid.

Soluble in 100% ethanol (>25mg/ml) and DMSO (>50mg/ml).

Formula: C₂₄H₄₇NO₃
Storage Temperature: Freezer

MDL Number: MFCD00870174
CAS Number: 124753-97-5

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