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Product Image-CA2301-66

FerroZine® Iron Reagent Solution Pillows, Hach

Catalog Number: (CA2301-66)
Supplier: Hach
Description: For determination of trace levels of iron by the Ferrozine method
Image Unavailable-TCF0005-500G

Ferroin (1,10-phenanthrolineferrous sulfate complex) in solution acc. JIS K8001

Supplier: TCI America
Description: CAS Number: 14634-91-4 MDL Number: MFCD00036428 Form: Liquid Color: Yellow Red

SDS

Product Image-10104-168

Anti-FTH1 Rabbit Polyclonal Antibody

Catalog Number: (10104-168)
Supplier: Prosci
Description: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Image Unavailable-10664-312

Anti-MMS19 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10664-312)
Supplier: Bioss
Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Image Unavailable-10664-308

Anti-MMS19 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10664-308)
Supplier: Bioss
Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Product Image-470236-112

Hematite (Specular) Slab

Catalog Number: (470236-112)
Supplier: ADAM MOORE MO
Description: Beautifully polished micaceous iron ore.
Image Unavailable-76109-546

Anti-MMS19 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76109-546)
Supplier: Bioss
Description: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
Image Unavailable-10664-986

Anti-HAMP Rabbit Polyclonal Antibody

Catalog Number: (10664-986)
Supplier: Bioss
Description: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].
Product Image-77522-890

Rat IREB2 (Iron Responsive Element Binding Protein 2) ELISA Kit

Catalog Number: (77522-890)
Supplier: AFG Bioscience
Description: Rat IREB2 (Iron Responsive Element Binding Protein 2) ELISA Kit
Image Unavailable-CAAA36190-09

Diiron arsenide ≥99.5% (metals basis)

Catalog Number: (CAAA36190-09)
Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00151533

Certificates


Image Unavailable-CA80051-292

Calbiochem® Human Native Ceruloplasmin (from Plasma)

Catalog Number: (CA80051-292)
Supplier: MilliporeSigma
Description: Serum copper transport and iron-oxidizing protein. Plays an important role in antioxidant protection against organic and inorganic oxygen radicals generated by iron and ascorbate. Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Certificates


Product Image-10099-798

Anti-SLC25A28 Rabbit Polyclonal Antibody

Catalog Number: (10099-798)
Supplier: Prosci
Description: SLC25A28 is a mitochondrial iron transporter that mediates iron uptake. It is probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells. The iron delivered into the mitochondria, presumably as Fe (2+), is then probably delivered to ferrochelatase to catalyze Fe (2+) incorporation into protoprophyrin IX to make heme.
Image Unavailable-CA1.03098.0025

2,2'-Bipyridyl ACS, GR for analysis, reagent for iron(II) and molybdenum, Supelco®

Supplier: MilliporeSigma
Description: Reagent for iron(II) and molybdenum

SDS Certificates

Image Unavailable-75791-062

Human Recombinant Hepcidin (from E. coli)

Catalog Number: (75791-062)
Supplier: Prosci
Description: Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.
Product Image-10797-006

Human Recombinant Betalobulin (from HEK293 cells)

Catalog Number: (10797-006)
Supplier: Prosci
Description: ?2 microglobulin is also known as Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).
Image Unavailable-CA80054-768

Human Transferrin Apo- (from Plasma)

Catalog Number: (CA80054-768)
Supplier: MilliporeSigma
Description: Native apotransferrin from human plasma. Transferrin is a serum protein involved in iron binding and transport. Substantially iron-free. Cell culture-tested.

Certificates


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