You Searched For: Choline+dihydrogen+citrate

Catalog Number: (10100-200)

Supplier: Prosci

Description: SGMS2 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. SGMS2 directly and specifically recognizes the choline head group on the substrate. SGMS2 also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. SGMS2 does not function strictly as a SM synthase. SGMS2 is required for cell growth.Sphingomyelin (SM) is a major component of plasma membranes. It is preferentially concentrated in the outer leaflet and has a role in the formation of lipid rafts. SM synthases (EC 2.7.8.27), such as SGMS2, produce SM in the lumen of the Golgi and on the cell surface through the transfer of phosphocholine from phosphatidylcholine onto ceramide, yielding diacylglycerol as a side product (Huitema et al., 2004 [PubMed 14685263]).

Catalog Number: (10099-814)

Supplier: Prosci

Description: SLC44A3 is a multi-pass membrane protein. It belongs to the CTL (choline transporter-like) family. The function of the RBM34 protein remains unknown.

Catalog Number: (CAJT4008-5)

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Crystals. For LC and molecular biology. Lot analysis on label.

Certificates

Catalog Number: (77052-572)

Supplier: ANTIBODIES.COM LLC

Description: Rabbit polyclonal antibody to Choactase for WB and ELISA with samples derived from Human, Mouse and Rat.

Catalog Number: (10396-662)

Supplier: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

Catalog Number: (CA80052-866)

Supplier: MilliporeSigma

Description: Lecithin (from soy bean)

Certificates

Catalog Number: (76078-194)

Supplier: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

Supplier: VWR International

Description: Suitable as a titrant. Made with deionized water.

SDS Certificates

Catalog Number: (CAJT7390-19)

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Potassium dihydrogen phosphate 98.0-100.5% (dried basis) NF, ACS, J.T.Baker®

Certificates

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Certificate of lot analysis provided.

Certificates

Supplier: BDH

Description: For LC, HPLC, and trace organic analysis.

SDS Certificates

Catalog Number: (10814-048)

Supplier: Prosci

Description: Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Description: Crystals. GMP manufactured.

Certificates

Supplier: Thermo Scientific Chemicals

Description: Naturally occuring lipid that protects cells from oxidation. Useful as an emulsifier

Certificates

Catalog Number: (10085-922)

Supplier: Proteintech

Description: DMGDH(Dimethylglycine dehydrogenase, mitochondrial) is also named as ME2GLYDH and belongs to the GcvT family. It catalyzes the oxidative demethylation of dimethylglycine to form sarcosine and it plays a role in choline catabolism in the liver. The full length protein has a transit peptide.

Catalog Number: (10402-122)

Supplier: Bioss

Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.