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Image Unavailable-89359-696

Anti-SOD1 Rabbit Polyclonal Antibody

Catalog Number: (89359-696)
Supplier: Genetex
Description: Superoxide dismutase (SOD) is responsible for the elimination of cytotoxic active oxygen by catalyzing the dismutation of the superoxide radical to oxygen and hydrogen peroxide. There are three SOD isoenzymes in mammalian cells. They are: extracellular SOD (EC SOD), copper and zinc-containing SOD (CuZn SOD) and manganese-containing SOD (Mn SOD). The CuZn form contains Cu and Zn ions and exists as a 32 kDa dimer in the cytosol. Mn SOD is an 80 kDa tetramer that contains Mn ion and resides in the mitochondrial matrix. Mn SOD is a tumor necrosis factor (TNF)- inducible enzyme that protects cells from TNF-mediated apoptosis via superoxide anion detoxification and the subsequent regulation of apoptosis through cytochrome c release and the modulation of the redox state of the mitochondria. Mn SOD has also been shown to be a tumor suppressor in human breast cancer. Overexpression of this enzyme protects neurons from NMDA- and nitric oxide-induced neurotoxicity.
Product Image-RC1821-16

Calcium Standard Stock Solution (1000 ppm Ca), Ricca Chemical Company

Catalog Number: (RC1821-16)
Supplier: Ricca Chemical
Description: Stock Solution (1000 ppm Ca). Poly Bottle. 500mL

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Image Unavailable-TCD1869-025G

Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate ≥98.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 207226-35-5
MDL Number: MFCD00150947
Molecular Formula: C14H23N3O10
Molecular Weight: 497.36
Purity/Analysis Method: >98.0% (T)
Form: Crystal

Image Unavailable-CAAA40136-36

Calcium iodide hydrate ≥98%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00149622 Freely soluble in water and alcohol

Certificates

Product Image-RCRV010269100N

VeriSpec® Calcium Standard for ICP 1000 ppm in 2% HCl

Supplier: Ricca Chemical
Description: Certified reference material (CRM) for ICP

SDS

Image Unavailable-10389-502

Anti-CCS Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10389-502)
Supplier: Bioss
Description: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Image Unavailable-10389-504

Anti-CCS Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10389-504)
Supplier: Bioss
Description: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Product Image-RC179816

Calcium Standard, 1 ml = 0.2 mg CaCO₃, 200 ppm CaCO₃ (80.09 ppm Ca), Ricca Chemical Company

Catalog Number: (RC179816)
Supplier: Ricca Chemical
Description: 1 mL = 0.2 mg CaCO3, 200 ppm CaCO3 (80.09 ppm Ca). ASTM D 1126 for Water Hardness. Poly Bottle. 500mL

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Image Unavailable-10772-776

Human Recombinant PEDF (from E. coli)

Supplier: Peprotech
Description: PEDF is a noninhibitory serpin with neurotrophic, anti-angiogenic, and anti-tumorigenic properties. It is a 50 kDa glycoprotein produced and secreted in many tissues throughout the body. A major component of the anti-angiogenic action of PEDF is the induction of apoptosis in proliferating endothelial cells. In addition, PEDF is able to inhibit the activity of angiogenic factors, such as VEGF and FGF-2. The neuroprotective effects of PEDF are achieved through suppression of neuronal apoptosis induced by peroxide, glutamate, or other neurotoxins. The recent identification of a lipase-linked cell membrane receptor for PEDF (PEDF-R) that binds to PEDF with high affinity ( Notari, I. et al. J Biol Chem., Vol. 281, 38022-38037 ) should facilitate further elucidation of the underlying mechanisms of this pluripotent serpin. To date, PEDF-R is the only signaling receptor known to be used by a serpin family member. The unique range of PEDF activities implicate it as a potential therapeutic agent for the treatment of vasculature-related neurodegenerative diseases, such as age-related macular degeneration (AMD) and proliferative diabetic retinopathy (PDR). PEDF also has the potential to be useful in the treatment of various angiogenesis-related diseases including a number of cancers. Recombinant Human PEDF is a 44.5 kDa non-glycosylated protein containing 400 amino acid residues.

Product Image-RC1795-100

Calcium IC Standard, 1 ml = 0.100 mg Ca, 100 ppm Ca CaCO₃in 3% HNO₃, Ricca Chemical Company

Catalog Number: (RC1795-100)
Supplier: Ricca Chemical
Description: 1 mL = 0.100 mg Ca, 100 ppm Ca CaCO3in 3% HNO3. 100 ppm Ca ion in water. For use in standardizing atomic absorption spectrophotometers. Poly Bottle. 100mL

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Product Image-34118-118

Orion™ Calcium Electrodes, Thermo Scientific

Supplier: Thermo Fisher Scientific
Description: Measure calcium in aqueous solutions simply, accurately, and economically with Orion™ Calcium Electrodes.

Image Unavailable-SXORG-CA8-4Z

Calcium Single-Element Organometallic Oil Standard for AA and ICP, SPEX CertiPrep

Supplier: SPEX CERTIPREP LLC
Description: Organometallic single-element oil standards are guaranteed stable and accurate, together with a wide range of applications and features:

Image Unavailable-CAAA88057-AP

Calcium, AAS Standard Solution, Specpure®, Ca 1000 mg/ml, Thermo Scientific

Supplier: Thermo Scientific Chemicals
Description: Molecular Formula: CaCO3 in 5% HNO3
Physical Form: Liquid
UN No.: 3264
MDL No.: MFCD00085314

Certificates

Image Unavailable-CAAA41589-09

Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)calcium ≥99.99% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)calcium ≥99.99% (metals basis)

Certificates

Product Image-RCRV010335500N

VeriSpec® Calcium Standard for ICP 1000 ppm in 2% HNO₃

Supplier: Ricca Chemical
Description: Certified reference material (CRM) for ICP

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Image Unavailable-10389-498

Anti-CCS Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10389-498)
Supplier: Bioss
Description: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
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