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Image Unavailable-10395-208

Anti-GPX4 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10395-208)
Supplier: Bioss
Description: Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.
Image Unavailable-CAAA40134-09

Calcium trifluoromethanesulfonate ≥99%

Supplier: Thermo Scientific Chemicals
Description: Calcium trifluoromethanesulfonate ≥99%

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Product Image-470300-624

Calcium Nitrate 4-Hydrate

Supplier: Ward's Science
Description: CAS Number: 13477-34-4
Formula Weight: 236.15
Formula: Ca(NO3)2·4H2O
Hazard Info: Flammable, Oxidizer, Explosive
Density (g/mL): 2.36
Boiling Point (°C): Decomposes
Freezing Point (°C): 45
Solubility: Water, Alcohol and Acetone
Synonyms: Calcium Nitrate Tetrahydrate, Nitric Acid Calcium(II) Salt
Shelf Life (months): 12
Storage: Yellow

SDS

Product Image-RC1785-1

Calcium hydroxide saturated solution in water USP Test Solution (TS)

Supplier: Ricca Chemical
Description: Multicompendial test reagent.

Image Unavailable-CAAAA44776-30

Calcium oxide ≥99.95% (metals basis)

Supplier: Thermo Scientific Chemicals
Description: Calcium oxide ≥99.95% (metals basis)

Certificates

Product Image-RC1823-16

Calcium sulfate solution R, saturated

Catalog Number: (RC1823-16)
Supplier: Ricca Chemical
Description: Saturated Aqueous Solution. Poly Bottle. 500mL

SDS Certificates Small Business Enterprise


Image Unavailable-10435-540

Anti-ALOX15B Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10435-540)
Supplier: Bioss
Description: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.
Image Unavailable-75788-602

Human Recombinant AIF (from E. coli)

Catalog Number: (75788-602)
Supplier: Prosci
Description: Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces parthanatos i.e., caspase-independent fragmentation of chromosomal DNA. AIFM1 interacts with EIF3G, and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. It binds to DNA in a sequence-independent manner and plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
Image Unavailable-10396-668

Anti-SGMS1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10396-668)
Supplier: Bioss
Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
Image Unavailable-10402-122

Anti-SGMS1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10402-122)
Supplier: Bioss
Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
Image Unavailable-76078-196

Anti-Sphingomyelin Synthase 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76078-196)
Supplier: Bioss
Description: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically recognizes the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
Image Unavailable-CAAA89750-P5

Calcium sulfate, Drierite™ 3 mm (8 mesh) for drying

Supplier: Thermo Scientific Chemicals
Description: Calcium sulfate, Drierite™ 3 mm (8 mesh) for drying

Image Unavailable-76120-914

Anti-Aconitase 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76120-914)
Supplier: Bioss
Description: Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IREBP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
Image Unavailable-10229-608

Anti-AIFM1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10229-608)
Supplier: Bioss
Description: Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.
Image Unavailable-10229-616

Anti-AIFM1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10229-616)
Supplier: Bioss
Description: Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions as a proapoptotic factor in a caspase-independent pathway. In contrast, functions as an antiapoptotic factor in normal mitochondria via its NADH oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces 'parthanatos' i.e. caspase-independent fragmentation of chromosomal DNA. Interacts with EIF3G,and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. Plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells. Binds to DNA in a sequence-independent manner.
Image Unavailable-CA1.02059.0500

Calcium carbonate, Suprapur® for trace metal analysis, Supelco®

Supplier: MilliporeSigma
Description: Calcium carbonate, Suprapur® for trace metal analysis, Supelco®

Certificates

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